JP6479209B2 - ケラチノサイトの脂質含量を増加させるための組成物 - Google Patents
ケラチノサイトの脂質含量を増加させるための組成物 Download PDFInfo
- Publication number
- JP6479209B2 JP6479209B2 JP2017549707A JP2017549707A JP6479209B2 JP 6479209 B2 JP6479209 B2 JP 6479209B2 JP 2017549707 A JP2017549707 A JP 2017549707A JP 2017549707 A JP2017549707 A JP 2017549707A JP 6479209 B2 JP6479209 B2 JP 6479209B2
- Authority
- JP
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- Prior art keywords
- skin
- extract
- keratinocytes
- composition
- lipid content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000000203 mixture Substances 0.000 title claims description 28
- 150000002632 lipids Chemical class 0.000 title description 23
- 210000002510 keratinocyte Anatomy 0.000 title description 16
- 239000000284 extract Substances 0.000 claims description 37
- 230000000699 topical effect Effects 0.000 claims description 11
- 230000037303 wrinkles Effects 0.000 claims description 10
- 239000011347 resin Substances 0.000 claims description 6
- 229920005989 resin Polymers 0.000 claims description 6
- 241001474374 Blennius Species 0.000 claims description 5
- 241000159174 Commiphora Species 0.000 claims description 4
- 210000003491 skin Anatomy 0.000 description 35
- 230000007935 neutral effect Effects 0.000 description 17
- 235000010659 Phoenix dactylifera Nutrition 0.000 description 11
- 241000233805 Phoenix Species 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 10
- 239000004615 ingredient Substances 0.000 description 9
- 239000013543 active substance Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 210000002950 fibroblast Anatomy 0.000 description 6
- 210000001789 adipocyte Anatomy 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 210000004207 dermis Anatomy 0.000 description 5
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 4
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 4
- 210000002744 extracellular matrix Anatomy 0.000 description 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 4
- 239000012071 phase Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 240000003890 Commiphora wightii Species 0.000 description 2
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- 229920001296 polysiloxane Polymers 0.000 description 2
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- 238000003786 synthesis reaction Methods 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 206010012434 Dermatitis allergic Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 108050001049 Extracellular proteins Proteins 0.000 description 1
- 102000016359 Fibronectins Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- PTNJRKBWIYNFSY-UHFFFAOYSA-N Lirinin-O-methyl-ether Natural products COc1ccc-2c(CC3N(C)CCc4cc(OC)c(OC)c-2c34)c1 PTNJRKBWIYNFSY-UHFFFAOYSA-N 0.000 description 1
- 244000104275 Phoenix dactylifera Species 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 241000221095 Simmondsia Species 0.000 description 1
- 235000004433 Simmondsia californica Nutrition 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- LQSNPVIQIPKOGP-UHFFFAOYSA-N UNPD159785 Natural products OC1C(O)C(O)C(CO)OC1OC1=C(O)C=C(O)C2=C1OC(C=1C=C(O)C(O)=CC=1)=CC2=O LQSNPVIQIPKOGP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001028 anti-proliverative effect Effects 0.000 description 1
- 230000002086 anti-sebum Effects 0.000 description 1
- 230000001153 anti-wrinkle effect Effects 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 239000002012 ayurvedic medicine Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
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- 239000000872 buffer Substances 0.000 description 1
- 239000004067 bulking agent Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000002024 ethyl acetate extract Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000030214 innervation Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000004611 light stabiliser Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000004940 nucleus Anatomy 0.000 description 1
- -1 pH adjusters Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000011049 pearl Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 210000000229 preadipocyte Anatomy 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000028201 sequestering of triglyceride Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Description
ケラチノサイトを含めて、多くの細胞型においては、中性脂質は中性脂質滴において濃縮される。調査中の物質によるケラチノサイトの処置に続いて、細胞試料を中性脂質滴に対して特異的親和性を有する染料で染色し、それらの容積変化を測定した。
コミフェロリン(Commipheroline) - コミフォラ・ムクル樹脂抽出物(90%トリ(カプリル酸/カプリン酸)グリセリル、10%コミフォラ・ムクル樹脂抽出物)の市販形態
タリップス(Thallips) - 海藻抽出物(99%トリ(カプリル酸/カプリン酸)グリセリル、1%藻類(海藻)抽出物)の市販形態
D'Orientine(商標) S - デーツパーム抽出物(95.9%トリ(カプリル酸/カプリン酸)グリセリル、3%ナツメヤシ果実抽出物、1%アブラナステロールズ(rapeseed sterols)、0.1%トコフェロール)の市販形態
Claims (1)
- コミフォラ・ムクル樹脂抽出物0.001〜3.0重量%、ナツメヤシの抽出物0.001〜3.0重量%、及び海藻抽出物0.001〜5.0重量%を含む、皮膚のしわを処置するための局所用組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562138626P | 2015-03-26 | 2015-03-26 | |
US62/138,626 | 2015-03-26 | ||
PCT/US2016/021704 WO2016153797A1 (en) | 2015-03-26 | 2016-03-10 | Compositions for increasing the lipid content of keratinocytes |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018509444A JP2018509444A (ja) | 2018-04-05 |
JP6479209B2 true JP6479209B2 (ja) | 2019-03-06 |
Family
ID=56973837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017549707A Active JP6479209B2 (ja) | 2015-03-26 | 2016-03-10 | ケラチノサイトの脂質含量を増加させるための組成物 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20160279052A1 (ja) |
EP (1) | EP3273939A4 (ja) |
JP (1) | JP6479209B2 (ja) |
KR (1) | KR20170118885A (ja) |
CN (1) | CN107427455A (ja) |
AU (1) | AU2016235861B2 (ja) |
CA (1) | CA2977557A1 (ja) |
WO (1) | WO2016153797A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3086172B1 (fr) * | 2018-09-26 | 2021-01-29 | Gallinee | Formulation cosmetique |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07101871A (ja) * | 1992-12-24 | 1995-04-18 | Lion Corp | 生体ヒアルロン酸合成促進剤 |
FR2738565B1 (fr) * | 1995-09-13 | 1997-11-28 | Dior Christian Parfums | Produits extraits d'une plante du genre commiphora, en particulier de la plante commiphora mukul, et extraits en contenant et leurs applications notamment en cosmetique |
US20070003536A1 (en) * | 2000-11-21 | 2007-01-04 | Zimmerman Amy C | Topical skin compositions, their preparation, and their use |
US20030095959A1 (en) * | 2000-11-21 | 2003-05-22 | Access Business Group International Llc. | Topical skin composition |
FR2871061B1 (fr) * | 2004-06-04 | 2007-08-10 | Coletica Sa | Principe actif capable d'induire la transformation du tgbf- latent inactif en tgfb actif |
US20060104931A1 (en) * | 2004-11-12 | 2006-05-18 | Takeshi Fukutome | Cosmetic treatment article comprising substrate and gel composition |
WO2008070368A2 (en) * | 2006-11-01 | 2008-06-12 | Living Proof, Inc. | Methods and compositions for skin care |
WO2008134712A2 (en) * | 2007-04-30 | 2008-11-06 | Living Proof, Inc. | Use of matrix metalloproteinase inhibitors in skin care |
WO2010056229A1 (en) * | 2008-11-13 | 2010-05-20 | Edward Hall | Nutritional supplements and their methods of formulation |
AU2010248058A1 (en) * | 2009-05-11 | 2011-12-22 | Elc Management Llc | Extended moisturization cosmetic compositions |
WO2010145008A1 (en) * | 2009-06-17 | 2010-12-23 | UNIVERSITé LAVAL | Use of skin care compositions comprising laminariacea extract for treatment of skin aging signs |
KR20140069279A (ko) * | 2011-09-30 | 2014-06-09 | 이엘씨 매니지먼트 엘엘씨 | 실리콘 유화제-비함유 천연 유화제계를 갖는 개인 조성물 |
ES2424294B1 (es) * | 2012-03-22 | 2014-07-21 | Lipotec, S.A. | Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas |
FR2988606B1 (fr) * | 2012-03-30 | 2014-08-08 | Sederma Sa | Composition topique comprenant des oligosaccharides sulfates bioactifs et utilisations cosmetiques |
WO2013149323A1 (en) * | 2012-04-02 | 2013-10-10 | Ntegrity | Natural products for skin care |
CA2921456C (en) * | 2013-08-15 | 2020-05-26 | Mary Kay Inc. | Topical skin compositions for treating wrinkles |
-
2016
- 2016-03-10 EP EP16769314.2A patent/EP3273939A4/en not_active Withdrawn
- 2016-03-10 CA CA2977557A patent/CA2977557A1/en not_active Abandoned
- 2016-03-10 WO PCT/US2016/021704 patent/WO2016153797A1/en unknown
- 2016-03-10 CN CN201680018497.7A patent/CN107427455A/zh active Pending
- 2016-03-10 KR KR1020177026633A patent/KR20170118885A/ko not_active Application Discontinuation
- 2016-03-10 JP JP2017549707A patent/JP6479209B2/ja active Active
- 2016-03-10 AU AU2016235861A patent/AU2016235861B2/en active Active
- 2016-03-11 US US15/067,275 patent/US20160279052A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3273939A1 (en) | 2018-01-31 |
KR20170118885A (ko) | 2017-10-25 |
AU2016235861B2 (en) | 2018-07-19 |
JP2018509444A (ja) | 2018-04-05 |
CA2977557A1 (en) | 2016-09-29 |
AU2016235861A1 (en) | 2017-09-07 |
EP3273939A4 (en) | 2018-12-05 |
CN107427455A (zh) | 2017-12-01 |
WO2016153797A1 (en) | 2016-09-29 |
US20160279052A1 (en) | 2016-09-29 |
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