JP6475620B2 - グルカンポリマー生成のためのグルコシルトランスフェラーゼ酵素 - Google Patents
グルカンポリマー生成のためのグルコシルトランスフェラーゼ酵素 Download PDFInfo
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- JP6475620B2 JP6475620B2 JP2015533292A JP2015533292A JP6475620B2 JP 6475620 B2 JP6475620 B2 JP 6475620B2 JP 2015533292 A JP2015533292 A JP 2015533292A JP 2015533292 A JP2015533292 A JP 2015533292A JP 6475620 B2 JP6475620 B2 JP 6475620B2
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- Prior art keywords
- seq
- glucan
- gtf
- enzyme
- poly
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01005—Dextransucrase (2.4.1.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01267—Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase (2.4.1.267)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261705180P | 2012-09-25 | 2012-09-25 | |
| US201261705178P | 2012-09-25 | 2012-09-25 | |
| US201261705177P | 2012-09-25 | 2012-09-25 | |
| US201261705181P | 2012-09-25 | 2012-09-25 | |
| US201261705179P | 2012-09-25 | 2012-09-25 | |
| US61/705,180 | 2012-09-25 | ||
| US61/705,179 | 2012-09-25 | ||
| US61/705,178 | 2012-09-25 | ||
| US61/705,181 | 2012-09-25 | ||
| US61/705,177 | 2012-09-25 | ||
| PCT/US2013/061579 WO2014052386A2 (en) | 2012-09-25 | 2013-09-25 | Glucosyltransferase enzymes for production of glucan polymers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529096A JP2015529096A (ja) | 2015-10-05 |
| JP2015529096A5 JP2015529096A5 (enExample) | 2016-11-10 |
| JP6475620B2 true JP6475620B2 (ja) | 2019-02-27 |
Family
ID=49322736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533292A Active JP6475620B2 (ja) | 2012-09-25 | 2013-09-25 | グルカンポリマー生成のためのグルコシルトランスフェラーゼ酵素 |
Country Status (17)
| Country | Link |
|---|---|
| US (13) | US8871474B2 (enExample) |
| EP (1) | EP2900828B1 (enExample) |
| JP (1) | JP6475620B2 (enExample) |
| KR (1) | KR20150058478A (enExample) |
| CN (1) | CN104838010B (enExample) |
| AU (1) | AU2013323686B2 (enExample) |
| BR (1) | BR112015006569A2 (enExample) |
| CA (1) | CA2884950C (enExample) |
| IL (1) | IL237610A0 (enExample) |
| IN (1) | IN2015DN01881A (enExample) |
| MX (1) | MX373253B (enExample) |
| MY (1) | MY166801A (enExample) |
| NZ (1) | NZ705700A (enExample) |
| PH (1) | PH12015500661B1 (enExample) |
| RU (1) | RU2015115644A (enExample) |
| SG (1) | SG11201502342YA (enExample) |
| WO (1) | WO2014052386A2 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9034092B2 (en) | 2012-05-24 | 2015-05-19 | E I Du Pont De Nemours And Company | Composition for preparing polysaccharide fibers |
| US9169506B2 (en) | 2013-09-05 | 2015-10-27 | E I Du Pont De Nemours And Company | Process for producing alpha-1,3-glucan polymer with reduced molecular weight |
| EP4163305B1 (en) | 2013-12-16 | 2024-07-10 | Nutrition & Biosciences USA 4, Inc. | Use of poly alpha-1,3-glucan ethers as viscosity modifiers |
| KR102410391B1 (ko) | 2013-12-18 | 2022-06-16 | 뉴트리션 앤드 바이오사이언시스 유에스에이 4, 인크. | 양이온성 폴리 알파-1,3-글루칸 에테르 |
| CN106103551A (zh) | 2014-01-06 | 2016-11-09 | 纳幕尔杜邦公司 | 聚α‑1,3‑葡聚糖膜的制备 |
| WO2015109066A1 (en) | 2014-01-17 | 2015-07-23 | E. I. Du Pont De Nemours And Company | Production of poly alpha-1,3-glucan formate films |
| WO2015123327A1 (en) * | 2014-02-14 | 2015-08-20 | E. I. Du Pont De Nemours And Company | Glucosyltransferase enzymes for production of glucan polymers |
| US9988657B2 (en) | 2014-02-27 | 2018-06-05 | E I Du Pont De Nemours And Company | Enzymatic hydrolysis of disaccharides and oligosaccharides using alpha-glucosidase enzymes |
| US9695253B2 (en) | 2014-03-11 | 2017-07-04 | E I Du Pont De Nemours And Company | Oxidized poly alpha-1,3-glucan |
| AU2015236336B2 (en) | 2014-03-25 | 2018-07-05 | Nutrition & Biosciences USA 4, Inc. | Production of glucan polymers from alternate sucrose sources |
| BR112016027887A2 (pt) * | 2014-05-29 | 2017-10-24 | Du Pont | composições de fibra e de carboidrato, produto alimentício, métodos para produzir uma composição de fibra, para produzir uma composição de carboidratos misturada, método para reduzir o índice glicêmico, método para inibir a elevação do nível de açúcar no sangue, composição cosmética, uso da composição e composição |
| CN106414506A (zh) * | 2014-05-29 | 2017-02-15 | 纳幕尔杜邦公司 | 可溶性葡聚糖纤维的酶促合成 |
| MX2016015612A (es) * | 2014-05-29 | 2017-03-13 | Du Pont | Síntesis enzimática de fibra soluble de glucano. |
| US10351633B2 (en) | 2014-05-29 | 2019-07-16 | E I Du Pont De Nemours And Company | Enzymatic synthesis of soluble glucan fiber |
| WO2015195777A1 (en) | 2014-06-19 | 2015-12-23 | E. I. Du Pont De Nemours And Company | Compositions containing one or more poly alpha-1,3-glucan ether compounds |
| US9714403B2 (en) | 2014-06-19 | 2017-07-25 | E I Du Pont De Nemours And Company | Compositions containing one or more poly alpha-1,3-glucan ether compounds |
| WO2015200612A1 (en) * | 2014-06-26 | 2015-12-30 | E. I. Du Pont De Nemours And Company | Production of poly alpha-1,3-glucan food casings |
| BR112017013368B1 (pt) | 2014-12-22 | 2021-11-23 | Nutrition & Biosciences USA 4, Inc. | Composição de mistura polimérica |
| EP3237455B1 (en) | 2014-12-22 | 2020-03-04 | DuPont Industrial Biosciences USA, LLC | Polysaccharide compositions for absorbing aqueous liquid |
| EP3253454B1 (en) | 2015-02-06 | 2020-04-22 | DuPont Industrial Biosciences USA, LLC | Colloidal dispersions of poly alpha-1,3-glucan based polymers |
| WO2016196021A1 (en) * | 2015-06-01 | 2016-12-08 | E I Du Pont De Nemours And Company | Structured liquid compositions comprising colloidal dispersions of poly alpha-1,3-glucan |
| WO2016205391A1 (en) | 2015-06-17 | 2016-12-22 | E I Du Pont De Nemours And Company | Modified glucosyltransferases for producing branched alpha-glucan polymers |
| ES2753181T3 (es) | 2015-08-28 | 2020-04-07 | Du Pont | Bencil-alfa-(1,3)-glucano y fibras del mismo |
| CN108350660B (zh) * | 2015-10-26 | 2022-04-29 | 营养与生物科学美国4公司 | 水不溶性α-(1,3→葡聚糖)组合物 |
| EP3368717B1 (en) | 2015-10-26 | 2022-12-14 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide coatings for paper |
| EP4137207B1 (en) | 2015-11-05 | 2024-07-17 | Nutrition & Biosciences USA 4, Inc. | Dextran-poly alpha-1,3-glucan graft copolymers and synthesis methods thereof |
| JP6970678B2 (ja) * | 2015-11-10 | 2021-11-24 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | グルカン不織ウェブ |
| WO2017083226A1 (en) | 2015-11-13 | 2017-05-18 | E. I. Du Pont De Nemours And Company | Glucan fiber compositions for use in laundry care and fabric care |
| WO2017083228A1 (en) | 2015-11-13 | 2017-05-18 | E. I. Du Pont De Nemours And Company | Glucan fiber compositions for use in laundry care and fabric care |
| WO2017083229A1 (en) * | 2015-11-13 | 2017-05-18 | E. I. Du Pont De Nemours And Company | Glucan fiber compositions for use in laundry care and fabric care |
| US10822383B2 (en) | 2015-11-26 | 2020-11-03 | E I Du Pont De Nemours And Company | Polypeptides capable of producing glucans having alpha-1,2 branches and use of the same |
| US10266861B2 (en) * | 2015-12-14 | 2019-04-23 | E. I. Du Pont De Nemours And Company | Production and composition of fructose syrup |
| US10895028B2 (en) | 2015-12-14 | 2021-01-19 | Dupont Industrial Biosciences Usa, Llc | Nonwoven glucan webs |
| US10664466B2 (en) * | 2016-03-08 | 2020-05-26 | Microsoft Technology Licensing, Llc. | Specific content distribution across documents |
| CN109714973B (zh) * | 2016-06-02 | 2022-03-04 | 雀巢产品有限公司 | α-葡聚糖 |
| WO2018052942A1 (en) | 2016-09-14 | 2018-03-22 | E. I. Du Pont De Nemours And Company | Engineered glucosyltransferases |
| EP3541850A1 (en) | 2016-11-16 | 2019-09-25 | E. I. du Pont de Nemours and Company | Molded article comprising polysaccharide |
| CN110291113B (zh) * | 2017-02-16 | 2022-03-04 | 营养与生物科学美国4公司 | 交联的右旋糖酐和交联的右旋糖酐-聚α-1,3-葡聚糖接枝共聚物 |
| CN110651049A (zh) * | 2017-05-23 | 2020-01-03 | 纳幕尔杜邦公司 | α-1,3-葡聚糖的酶促生产 |
| EP3668970A1 (en) * | 2017-09-13 | 2020-06-24 | DuPont Industrial Biosciences USA, LLC | Engineered glucosyltransferases |
| WO2019055373A1 (en) | 2017-09-13 | 2019-03-21 | E. I. Du Pont De Nemours And Company | Engineered glucosyltransferases |
| EP3658708B1 (en) | 2017-09-13 | 2024-03-06 | Nutrition & Biosciences USA 4, Inc. | Nonwoven webs comprising polysaccharides |
| EP3694891B1 (en) | 2017-10-13 | 2022-08-24 | Nutrition & Biosciences USA 4, Inc. | Flowable bulk granular polysaccharide |
| CN111566128B (zh) * | 2017-11-10 | 2022-06-21 | 营养与生物科学美国4公司 | 独特形态的多糖 |
| WO2019118674A1 (en) | 2017-12-14 | 2019-06-20 | E. I. Du Pont De Nemours And Company | Alpha-1,3-glucan graft copolymers |
| AU2019230061B2 (en) | 2018-03-09 | 2025-05-15 | Nutrition & Biosciences USA 4, Inc. | Engineered glucosyltransferases |
| MX2021000109A (es) * | 2018-07-05 | 2021-03-09 | Dupont Nutrition Biosci Aps | Uso de glucosil transferasa para proporcionar una mejor textura a productos a base de leche fermentada. |
| CN113574074B (zh) | 2018-10-25 | 2023-03-21 | 营养与生物科学美国第四公司 | α-1,3-葡聚糖接枝共聚物 |
| US20220033531A1 (en) | 2018-12-17 | 2022-02-03 | Dupont Industrial Biosciences Usa,Llc | Polysaccharide Derivatives and Compositions Comprising Same |
| US12389916B2 (en) | 2019-08-16 | 2025-08-19 | Nutrition & Biosciences USA 4, Inc. | Flour- and meal-based food products comprising insoluble alpha-1,3-glucan |
| AT522767B1 (de) | 2019-08-16 | 2021-01-15 | Mondi Ag | Transferpapier für Thermosublimationsdruck-Prozesse und Verfahren zur Herstellung von Transferpapier |
| EP4055063A1 (en) | 2019-11-06 | 2022-09-14 | Nutrition & Biosciences USA 4, Inc. | Highly crystalline alpha-1,3-glucan |
| CN115052905B (zh) | 2020-02-04 | 2024-06-11 | 营养与生物科学美国4公司 | 包含α-1,3糖苷键的不溶性α-葡聚糖的水性分散体 |
| EP4161972A1 (en) | 2020-06-04 | 2023-04-12 | Nutrition & Biosciences USA 4, Inc. | Dextran-alpha-glucan graft copolymers and derivatives thereof |
| CN116134055A (zh) | 2020-06-10 | 2023-05-16 | 营养与生物科学美国4公司 | 聚α-1,6-葡聚糖衍生物和包含其的组合物 |
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| US20240239921A1 (en) | 2021-05-04 | 2024-07-18 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising oxidized insoluble alpha-glucan |
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| AU2022354202A1 (en) | 2021-09-30 | 2024-03-14 | International N&H Denmark Aps | Method for reducing sugar in food stuff |
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| CN114717213B (zh) * | 2022-05-05 | 2023-09-22 | 广西科学院 | 一种葡聚糖蔗糖酶的n端截短突变酶及其制备方法 |
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| US20250339361A1 (en) | 2022-11-02 | 2025-11-06 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising xanthan gum and crystalline alpha-1,3-glucan |
| WO2024206631A1 (en) | 2023-03-29 | 2024-10-03 | International N&H Denmark Aps | Methods for modifying texture in foodstuff via preferably in situ produced alpha-glucan |
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| CN122249471A (zh) | 2023-09-29 | 2026-06-19 | 美国丹尼斯科公司 | 交联的α-葡聚糖衍生物 |
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| WO2026015598A2 (en) | 2024-07-11 | 2026-01-15 | International N&H Denmark Aps | Method to provide improved texture and stable sucrose levels in foodstuff with glucosyltransferase |
| WO2026024663A1 (en) | 2024-07-24 | 2026-01-29 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising alpha-glucan with alpha-1,3 glycosidic linkages |
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| WO2026063497A1 (ja) * | 2024-09-20 | 2026-03-26 | 天野エンザイム株式会社 | グルコシルトランスフェラーゼ |
| WO2026102382A2 (en) | 2024-11-11 | 2026-05-15 | International N&H Denmark Aps | Method for reducing sugar in foodstuff through conversion of fructose with epimerase |
| WO2026112560A1 (en) | 2024-11-25 | 2026-05-28 | International N&H Denmark Aps | Use of glucosyltransferase in dough preparation |
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| EP1001736A1 (en) | 1996-10-11 | 2000-05-24 | Novo Nordisk A/S | STARCH BINDING DOMAINS (SBDs) FOR ORAL CARE PRODUCTS |
| US5952205A (en) | 1998-02-06 | 1999-09-14 | Neose Technologies, Inc. | Process for processing sucrose into glucose and fructose |
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| US6867026B2 (en) | 2000-05-25 | 2005-03-15 | Nederlandse Organisatie Voor Toegepast Natuurwetenschappelijk Onderzoek Tno | Glucosyltransferases |
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| EP1679374A1 (en) | 2005-01-10 | 2006-07-12 | Bayer CropScience GmbH | Transformed plant expressing a mutansucrase and synthesizing a modified starch |
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| US8642757B2 (en) | 2011-09-09 | 2014-02-04 | E I Du Pont De Nemours And Company | High titer production of highly linear poly (α 1,3 glucan) |
| US9080195B2 (en) * | 2011-09-09 | 2015-07-14 | E I Du Pont De Nemours And Company | High titer production of poly (α 1,3 glucan) |
| WO2013096502A1 (en) * | 2011-12-19 | 2013-06-27 | E. I. Du Pont De Nemours And Company | INCREASED POLY (α 1, 3 GLUCAN) YIELD USING BORIC ACID |
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-
2013
- 2013-09-25 EP EP13774318.3A patent/EP2900828B1/en active Active
- 2013-09-25 CN CN201380049949.4A patent/CN104838010B/zh active Active
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