JP6474732B2 - 激痛治療用組成物と方法 - Google Patents
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- JP6474732B2 JP6474732B2 JP2015552092A JP2015552092A JP6474732B2 JP 6474732 B2 JP6474732 B2 JP 6474732B2 JP 2015552092 A JP2015552092 A JP 2015552092A JP 2015552092 A JP2015552092 A JP 2015552092A JP 6474732 B2 JP6474732 B2 JP 6474732B2
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- OTXNTMVVOOBZCV-WAZJVIJMSA-N γ-tocotrienol Chemical compound OC1=C(C)C(C)=C2O[C@@](CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)(C)CCC2=C1 OTXNTMVVOOBZCV-WAZJVIJMSA-N 0.000 description 1
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- 239000011729 δ-tocotrienol Substances 0.000 description 1
- ODADKLYLWWCHNB-LDYBVBFYSA-N δ-tocotrienol Chemical compound OC1=CC(C)=C2O[C@@](CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)(C)CCC2=C1 ODADKLYLWWCHNB-LDYBVBFYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201361752356P | 2013-01-14 | 2013-01-14 | |
US61/752,356 | 2013-01-14 | ||
PCT/EP2014/050628 WO2014108569A1 (fr) | 2013-01-14 | 2014-01-14 | Compositions et procédés destinés au traitement de la douleur aiguë |
Publications (3)
Publication Number | Publication Date |
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JP2016504401A JP2016504401A (ja) | 2016-02-12 |
JP2016504401A5 JP2016504401A5 (fr) | 2017-02-16 |
JP6474732B2 true JP6474732B2 (ja) | 2019-02-27 |
Family
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Application Number | Title | Priority Date | Filing Date |
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JP2015552092A Active JP6474732B2 (ja) | 2013-01-14 | 2014-01-14 | 激痛治療用組成物と方法 |
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Country | Link |
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EP (1) | EP2943183A1 (fr) |
JP (1) | JP6474732B2 (fr) |
KR (1) | KR20150129665A (fr) |
CN (1) | CN104968330A (fr) |
AU (1) | AU2014204739B2 (fr) |
BR (1) | BR112015015864B1 (fr) |
CA (1) | CA2897874A1 (fr) |
HK (1) | HK1217650A1 (fr) |
IL (1) | IL239921A0 (fr) |
MX (1) | MX2015009045A (fr) |
RU (1) | RU2677346C2 (fr) |
SG (1) | SG11201505245XA (fr) |
WO (1) | WO2014108569A1 (fr) |
ZA (1) | ZA201505005B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US11896037B2 (en) * | 2016-08-03 | 2024-02-13 | Temple University-Of The Commonwealth System Of Higher Education | Microencapsulation of active agents |
JP7027786B2 (ja) * | 2017-10-12 | 2022-03-02 | ライオン株式会社 | 筋・筋膜性疼痛用の内服治療剤 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
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US5143934A (en) * | 1990-11-21 | 1992-09-01 | A/S Dumex (Dumex Ltd.) | Method and composition for controlled delivery of biologically active agents |
GB9613858D0 (en) * | 1996-07-02 | 1996-09-04 | Cortecs Ltd | Hydrophobic preparations |
DK0989851T3 (da) * | 1997-07-29 | 2003-01-27 | Upjohn Co | Selvemulgerende formulering indeholdende sure lipofile forbindelser |
CA2294031E (fr) * | 1997-07-29 | 2012-04-03 | Pharmacia & Upjohn Company | Formulation autoemulsifiante pour composes lipophiles |
GB2331458B (en) * | 1997-11-21 | 2002-07-31 | Gursharan Singh Moonga | Solubilising systems for difficult pharmaceutical actives for preparing concentrated stable solutions for encapsulation into soft gelatine |
US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
MXPA01011343A (es) * | 1999-05-07 | 2002-06-04 | Pharmasol Gmbh | Particulas de lipidos a base de mezclas de lipidos liquidos y solidos asi como procedimiento para su produccion. |
US8663692B1 (en) * | 1999-05-07 | 2014-03-04 | Pharmasol Gmbh | Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same |
ATE251449T1 (de) * | 1999-06-14 | 2003-10-15 | Cosmo Spa | Geschmacksmaskierte orale pharmazeutische zusammensetzungen mit kontrollierter abgabe |
US6455067B1 (en) * | 2000-05-24 | 2002-09-24 | Sang-A Pharmaceutical Co., Ltd. | Transdermal patch for nonsteroidal antiinflammatory drug(s) |
JP2002284705A (ja) * | 2001-01-19 | 2002-10-03 | Shiseido Co Ltd | 刺激緩和剤 |
GB0402679D0 (en) * | 2004-02-06 | 2004-03-10 | Novartis Ag | Organic compounds |
KR20070084531A (ko) * | 2004-11-24 | 2007-08-24 | 머크 앤드 캄파니 인코포레이티드 | 치환된 아미드의 경구 투여용 액체 및 반고체 약제학적제형 |
KR20080023677A (ko) * | 2005-04-28 | 2008-03-14 | 갈레니카 테크놀로지 아베 | 지질상을 포함하는 약학적 투약 형태 |
GB0610867D0 (en) * | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
GB0704846D0 (en) * | 2007-03-13 | 2007-04-18 | Futura Medical Dev Ltd | Topical pharmaceutical formulation |
ES2423793T3 (es) | 2008-05-26 | 2013-09-24 | Genfit | Compuestos agonistas de PPAR, preparación y usos para el tratamiento de la diabetes y/o dislipidemias |
CN102048680B (zh) * | 2009-11-11 | 2013-05-01 | 河北奥星集团药业有限公司 | 一种含有扎托布洛芬的肠溶缓释制剂及其制备方法 |
WO2012104655A2 (fr) * | 2011-02-04 | 2012-08-09 | Biocopea Limited | Compositions et méthodes pour traiter l'inflammation chronique et les maladies inflammatoires |
CN102579350B (zh) * | 2012-03-02 | 2013-04-24 | 海南灵康制药有限公司 | 右旋布洛芬脂质体固体制剂 |
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2014
- 2014-01-14 BR BR112015015864-1A patent/BR112015015864B1/pt active IP Right Grant
- 2014-01-14 CN CN201480006249.1A patent/CN104968330A/zh active Pending
- 2014-01-14 JP JP2015552092A patent/JP6474732B2/ja active Active
- 2014-01-14 KR KR1020157020599A patent/KR20150129665A/ko not_active Application Discontinuation
- 2014-01-14 EP EP14702759.3A patent/EP2943183A1/fr not_active Withdrawn
- 2014-01-14 WO PCT/EP2014/050628 patent/WO2014108569A1/fr active Application Filing
- 2014-01-14 AU AU2014204739A patent/AU2014204739B2/en active Active
- 2014-01-14 CA CA2897874A patent/CA2897874A1/fr not_active Abandoned
- 2014-01-14 MX MX2015009045A patent/MX2015009045A/es unknown
- 2014-01-14 RU RU2015134136A patent/RU2677346C2/ru active IP Right Revival
- 2014-01-14 SG SG11201505245XA patent/SG11201505245XA/en unknown
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- 2015-07-14 IL IL239921A patent/IL239921A0/en unknown
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2016
- 2016-05-18 HK HK16105731.5A patent/HK1217650A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2014108569A1 (fr) | 2014-07-17 |
BR112015015864A8 (pt) | 2018-01-16 |
AU2014204739B2 (en) | 2016-08-11 |
HK1217650A1 (zh) | 2017-01-20 |
CN104968330A (zh) | 2015-10-07 |
RU2015134136A (ru) | 2017-02-20 |
ZA201505005B (en) | 2016-10-26 |
JP2016504401A (ja) | 2016-02-12 |
MX2015009045A (es) | 2015-12-17 |
EP2943183A1 (fr) | 2015-11-18 |
IL239921A0 (en) | 2015-08-31 |
KR20150129665A (ko) | 2015-11-20 |
RU2677346C2 (ru) | 2019-01-16 |
SG11201505245XA (en) | 2015-08-28 |
CA2897874A1 (fr) | 2014-07-17 |
BR112015015864A2 (pt) | 2017-07-11 |
AU2014204739A1 (en) | 2015-07-16 |
BR112015015864B1 (pt) | 2022-08-23 |
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