JP6461975B2 - 血液酸素付加装置 - Google Patents

血液酸素付加装置 Download PDF

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Publication number
JP6461975B2
JP6461975B2 JP2016542198A JP2016542198A JP6461975B2 JP 6461975 B2 JP6461975 B2 JP 6461975B2 JP 2016542198 A JP2016542198 A JP 2016542198A JP 2016542198 A JP2016542198 A JP 2016542198A JP 6461975 B2 JP6461975 B2 JP 6461975B2
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Prior art keywords
blood
fiber bundle
oxygenator
housing
oxygenated
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English (en)
Japanese (ja)
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JP2017507681A5 (enExample
JP2017507681A (ja
Inventor
ジョンジュン・ウー
バートリー・ピー・グリフィス
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University of Maryland Baltimore
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University of Maryland Baltimore
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1629—Constructional aspects thereof with integral heat exchanger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3623—Means for actively controlling temperature of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/109—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems
    • A61M60/113—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/226—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
    • A61M60/232—Centrifugal pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/30—Medical purposes thereof other than the enhancement of the cardiac output
    • A61M60/36—Medical purposes thereof other than the enhancement of the cardiac output for specific blood treatment; for specific therapy
    • A61M60/38—Blood oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3368—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/366—General characteristics of the apparatus related to heating or cooling by liquid heat exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/08—Supports for equipment
    • A61M2209/088—Supports for equipment on the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Mechanical Engineering (AREA)
  • Pulmonology (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
JP2016542198A 2013-12-23 2014-12-23 血液酸素付加装置 Active JP6461975B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361919837P 2013-12-23 2013-12-23
US61/919,837 2013-12-23
PCT/US2014/072046 WO2015100288A1 (en) 2013-12-23 2014-12-23 Blood oxygenator

Publications (3)

Publication Number Publication Date
JP2017507681A JP2017507681A (ja) 2017-03-23
JP2017507681A5 JP2017507681A5 (enExample) 2018-02-01
JP6461975B2 true JP6461975B2 (ja) 2019-01-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016542198A Active JP6461975B2 (ja) 2013-12-23 2014-12-23 血液酸素付加装置

Country Status (5)

Country Link
US (4) US10188780B2 (enExample)
EP (1) EP3086823B1 (enExample)
JP (1) JP6461975B2 (enExample)
CN (1) CN105828848B (enExample)
WO (1) WO2015100288A1 (enExample)

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CN105828848B (zh) * 2013-12-23 2019-01-18 马里兰大学，巴尔的摩 血液氧合器
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US20180001012A1 (en) * 2014-12-16 2018-01-04 The Regents Of The University Of California Portable Lung Assist Device
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CN115998976A (zh) * 2017-08-15 2023-04-25 马里兰大学巴尔的摩 双室气体交换器和用于呼吸支持的方法
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WO2019162526A1 (de) * 2018-02-26 2019-08-29 Hemovent Gmbh Halteeinrichtung zum halten eines oxygenators und einer blutpumpe
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RU190014U1 (ru) * 2018-07-24 2019-06-14 Александр Иванович Андреев Мембранный оксигенатор
CN109364367B (zh) * 2018-09-28 2021-01-01 东莞科威医疗器械有限公司 一种流量控制阀及离心注料装置
CN109224163B (zh) * 2018-10-16 2019-06-21 广东工业大学 一种热交换层外置的中空纤维膜式氧合器
CN109224165B (zh) * 2018-11-27 2025-03-14 苏州小帅医疗器械有限公司 一种带变温的集成离心泵的膜式氧合器
CN109364315B (zh) * 2018-12-07 2025-03-14 苏州小帅医疗器械有限公司 一种带变温双腔膜式氧合器
CN109481769B (zh) * 2018-12-11 2019-11-12 广东工业大学 一种带生物相容性涂层的膜式氧合器
CN110141705B (zh) * 2019-05-20 2020-02-04 杜乐栋 一种负压式外科手术血液处理设备
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WO2021054159A1 (ja) * 2019-09-17 2021-03-25 テルモ株式会社 人工肺
CN113144316B (zh) * 2020-01-22 2025-09-05 苏州肺盾医疗科技有限公司 膜式氧合器
CN111407945B (zh) * 2020-04-23 2025-03-25 美茵（北京）医疗器械研发有限公司 血液氧合流转装置
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CN111744066A (zh) * 2020-07-25 2020-10-09 昆明医科大学第一附属医院 抗凝血性中空纤维膜和过滤器
WO2022113020A1 (en) * 2020-11-27 2022-06-02 Slaski Uniwersytet Medyczny Blood oxygenator with an organic membrane
WO2022113018A2 (en) * 2020-11-27 2022-06-02 Uniwersytet Slaski Blood oxygenator with an organic membrane
CN113209406B (zh) * 2021-01-15 2022-04-26 苏州心擎医疗技术有限公司 体外膜肺氧合器
CN113398354B9 (zh) * 2021-07-14 2022-05-03 江苏赛腾医疗科技有限公司 集成式膜式氧合器
CN113499496B (zh) * 2021-07-14 2022-03-25 江苏赛腾医疗科技有限公司 内置过滤器的膜式氧合器
CN113509605B (zh) * 2021-07-14 2022-09-20 江苏赛腾医疗科技有限公司 膜式氧合器
CN113599605B (zh) * 2021-07-29 2024-02-20 深圳汉诺医疗科技有限公司 一种膜式氧合器
CN115920161B (zh) * 2022-07-13 2024-05-31 心擎医疗（苏州）股份有限公司 氧合器
CN115154719A (zh) * 2022-07-17 2022-10-11 江苏恰瑞生物科技有限公司 一种血液净化中副产物气体的吸收装置及吸收剂
CN115192807B (zh) * 2022-07-27 2024-06-18 北京航天长峰股份有限公司 一种氧合器及体外膜肺氧合装置
CN115607759B (zh) * 2022-10-31 2023-04-28 北京航空航天大学 一种血液氧合器
CN115887808A (zh) * 2022-12-27 2023-04-04 北京航空航天大学 膜式氧合器
EP4648815A1 (en) * 2023-01-09 2025-11-19 KOC Universitesi A blood oxygenator with reduced pressure drop
CN116036396A (zh) * 2023-01-31 2023-05-02 北京航空航天大学 一种膜式氧合器
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CN117122814B (zh) * 2023-10-25 2024-02-02 北京航天长峰股份有限公司 一种泵头氧合器组件和体外膜肺氧合系统
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CN117771461B (zh) * 2024-01-05 2024-11-26 江苏赛腾医疗科技有限公司 一种高效过滤氧合器

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EP3086823A1 (en) 2016-11-02
US10188780B2 (en) 2019-01-29
EP3086823B1 (en) 2018-11-21
WO2015100288A1 (en) 2015-07-02
EP3086823A4 (en) 2017-07-05
CN105828848B (zh) 2019-01-18
US20250213764A1 (en) 2025-07-03
US20190209761A1 (en) 2019-07-11
US20210346581A1 (en) 2021-11-11
JP2017507681A (ja) 2017-03-23
US20160296685A1 (en) 2016-10-13
US12178946B2 (en) 2024-12-31
CN105828848A (zh) 2016-08-03
US11065375B2 (en) 2021-07-20

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