IT1271104B - Ossigenatore di sangue con uno strato di capillari in membrana microporosa. - Google Patents
Ossigenatore di sangue con uno strato di capillari in membrana microporosa.Info
- Publication number
- IT1271104B IT1271104B ITMI942403A ITMI942403A IT1271104B IT 1271104 B IT1271104 B IT 1271104B IT MI942403 A ITMI942403 A IT MI942403A IT MI942403 A ITMI942403 A IT MI942403A IT 1271104 B IT1271104 B IT 1271104B
- Authority
- IT
- Italy
- Prior art keywords
- ribs
- capillaries
- layer
- contact
- external wall
- Prior art date
Links
- 239000008280 blood Substances 0.000 title abstract 3
- 210000004369 blood Anatomy 0.000 title abstract 3
- 239000012982 microporous membrane Substances 0.000 title abstract 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229920005749 polyurethane resin Polymers 0.000 abstract 1
- 238000004382 potting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3623—Means for actively controlling temperature of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/026—Wafer type modules or flat-surface type modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/033—Specific distribution of fibres within one potting or tube-sheet
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/14—Specific spacers
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Il presente trovato si riferisce ad un ossigenatore di sangue con struttura cilindrica dotata di una parete interna e di una parete esterna delimitanti una porzione di spazio per il contenimento di uno strato di capillari in membrana microporosa destinati ad essere lambiti esternamente dal sangue, che percorre con direzione sostanzialmente perpendicolare ai detti capillari la porzione di spazio dotata di vie di comunicazione con l'esterno. I capillari sono annegati alle estremità in anelli di resina poliuretanica denominati potting e aperti su camere rispettivamente di entrata di ossigeno e di uscita di anidride carbonica.La peculiarità del trovato è costituita dal fatto di comprendere nervature che si derivano dalla parte interna della struttura suddivise in una pluralità di gruppi estesi per tutta la lunghezza della struttura stessa.Le nervature sono atte a determinare un andamento ondulato dello strato di capillari, con presa di contatto da parte dello stesso con la parete esterna della struttura nelle zone di contatto con le nervature e distacco dalla parete esterna, con presa di contatto con la parete interna della struttura nelle zone comprese fra due gruppi adiacenti di nervature.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI942403A IT1271104B (it) | 1994-11-25 | 1994-11-25 | Ossigenatore di sangue con uno strato di capillari in membrana microporosa. |
| US08/560,625 US5817278A (en) | 1994-11-25 | 1995-11-20 | Blood oxygenator and method of oxygenating blood |
| DE69522780T DE69522780T2 (de) | 1994-11-25 | 1995-11-22 | Blutoxygenator |
| EP95118373A EP0713709B1 (en) | 1994-11-25 | 1995-11-22 | Blood oxygenator |
| AT95118373T ATE205733T1 (de) | 1994-11-25 | 1995-11-22 | Blutoxygenator |
| ES95118373T ES2161818T3 (es) | 1994-11-25 | 1995-11-22 | Oxigenador de sangre. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI942403A IT1271104B (it) | 1994-11-25 | 1994-11-25 | Ossigenatore di sangue con uno strato di capillari in membrana microporosa. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI942403A0 ITMI942403A0 (it) | 1994-11-25 |
| ITMI942403A1 ITMI942403A1 (it) | 1996-05-25 |
| IT1271104B true IT1271104B (it) | 1997-05-26 |
Family
ID=11369919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI942403A IT1271104B (it) | 1994-11-25 | 1994-11-25 | Ossigenatore di sangue con uno strato di capillari in membrana microporosa. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5817278A (it) |
| EP (1) | EP0713709B1 (it) |
| AT (1) | ATE205733T1 (it) |
| DE (1) | DE69522780T2 (it) |
| ES (1) | ES2161818T3 (it) |
| IT (1) | IT1271104B (it) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU700335B2 (en) * | 1995-03-22 | 1998-12-24 | Mechano Chemical Research Institute Ltd. | Method for desalinating salts-containing water and apparatus therefor |
| US5762875A (en) * | 1996-01-16 | 1998-06-09 | Medtronic, Inc. | Core structure for blood oxygenators |
| US6106776A (en) | 1997-04-11 | 2000-08-22 | University Of Pittsburgh | Membrane apparatus with enhanced mass transfer via active mixing |
| US6723284B1 (en) | 1997-04-11 | 2004-04-20 | University Of Pittsburgh | Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing |
| US6217826B1 (en) * | 1997-04-11 | 2001-04-17 | University Of Pittsburgh | Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing |
| US6350411B1 (en) | 1998-03-23 | 2002-02-26 | Celgard Inc. | Microporous hollow fiber blood oxygenator |
| US6267926B1 (en) | 1998-10-08 | 2001-07-31 | Celgard Inc. | Device for removing entrained gases from liquids |
| US6508983B1 (en) | 1999-07-19 | 2003-01-21 | Cobe Cardiovascular | Exchanger apparatus and method of manufacture |
| GB9924087D0 (en) | 1999-10-12 | 1999-12-15 | Maltin Christopher | Treatment of process fluids |
| IT1318742B1 (it) | 2000-08-08 | 2003-09-10 | Dideco Spa | Dispositivo ossigenatore del sangue in circuito extracorporeo. |
| US6802821B2 (en) * | 2001-10-01 | 2004-10-12 | Fresenius Usa, Inc. | Dialyzer |
| US6682698B2 (en) | 2001-08-23 | 2004-01-27 | Michigan Critical Care Consultants, Inc. | Apparatus for exchanging gases in a liquid |
| ITMI20021552A1 (it) * | 2002-07-15 | 2004-01-15 | Dideco Spa | Dispositivo per il trattamento di sangue in circuito extracorporeo |
| ITMI20030148U1 (it) * | 2003-04-01 | 2004-10-02 | Dideco Spa | Struttura di dispositivo per il trattamento di sangue in circolazione extracorporea |
| ITMI20030647A1 (it) * | 2003-04-01 | 2004-10-02 | Dideco Spa | Dispositivo per il trattamento di sangue in circolazione extracorporea |
| CN104524654A (zh) | 2005-04-21 | 2015-04-22 | 联邦高等教育系统匹兹堡大学 | 体外辅助呼吸器 |
| EP1810704B1 (en) * | 2006-01-19 | 2015-04-22 | Terumo Kabushiki Kaisha | Oxygenator |
| EP1930034B1 (en) | 2006-12-07 | 2012-11-14 | Thoratec LLC | An integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system |
| US8545754B2 (en) | 2009-04-23 | 2013-10-01 | Medtronic, Inc. | Radial design oxygenator with heat exchanger |
| IT1394992B1 (it) | 2009-07-28 | 2012-08-07 | Rand Srl | Dispositivo ossigenatore |
| US8318092B2 (en) | 2010-04-29 | 2012-11-27 | Sorin Group Italia S.R.L. | Oxygenator with integrated arterial filter |
| US8388566B2 (en) | 2010-04-29 | 2013-03-05 | Sorin Group Italia, S.r.l. | Oxygenator with integrated arterial filter including filter frame |
| IT1401551B1 (it) | 2010-06-28 | 2013-07-26 | Rand Srl | Dispositivo per ossigenare il sangue in circolazione extracorporea |
| EP2612685B1 (en) | 2010-08-19 | 2014-10-08 | Sorin Group Italia S.r.l. | Blood processing unit with modified flow path |
| EP2524712B1 (en) | 2011-05-17 | 2018-12-12 | Sorin Group Italia S.r.l. | Blood processing unit with cross blood flow |
| WO2012066439A1 (en) * | 2010-11-15 | 2012-05-24 | Sorin Group Italia S.R.L. | Blood processing unit with circumferential blood flow |
| JP5913345B2 (ja) * | 2010-11-15 | 2016-04-27 | ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータ | 円周方向血液流れの血液処理ユニット |
| US8795591B2 (en) * | 2011-01-27 | 2014-08-05 | Medtronic, Inc. | Dual outlet oxygenator for treating blood in an extracorporeal blood circuit |
| JP6461975B2 (ja) | 2013-12-23 | 2019-01-30 | ユニバーシティ・オブ・メリーランド・ボルティモアUniversity Of Maryland, Baltimore | 血液酸素付加装置 |
| US10098994B2 (en) | 2014-01-09 | 2018-10-16 | Sorin Group Italia S.R.L. | Blood processing unit with heat exchanger core for providing modified flow path |
| WO2015128886A1 (en) | 2014-02-28 | 2015-09-03 | Sorin Group Italia S.R.L. | System for providing an integrated arterial filter into an oxygenator, minimizing added priming volume |
| EP3218087A1 (en) | 2014-11-12 | 2017-09-20 | Sorin Group Italia S.r.l. | Elastic protection tube for a hollow fibre blood processing apparatus |
| EP3294368B1 (en) | 2015-05-12 | 2019-06-26 | Sorin Group Italia S.r.l. | Blood gas exchanger with restriction element or elements to reduce gas exchange |
| CN115998976A (zh) * | 2017-08-15 | 2023-04-25 | 马里兰大学巴尔的摩 | 双室气体交换器和用于呼吸支持的方法 |
| EP4252794A1 (en) | 2019-01-29 | 2023-10-04 | Nipro Corporation | Artificial lung device |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3422008A (en) * | 1963-10-24 | 1969-01-14 | Dow Chemical Co | Wound hollow fiber permeability apparatus and process of making the same |
| BE793624A (fr) * | 1972-01-10 | 1973-05-02 | Baxter Laboratories Inc | Dispositif pour le transfert de masses, presentant une membrane de diffision tubulaire enroulee |
| DE2721444A1 (de) | 1977-05-12 | 1978-11-16 | Fresenius Chem Pharm Ind | Hohlfaserdialysator |
| US4715953A (en) * | 1983-04-01 | 1987-12-29 | Baxter Travenol Laboratories, Inc. | Hollow fiber separation device manifold |
| US4622206A (en) * | 1983-11-21 | 1986-11-11 | University Of Pittsburgh | Membrane oxygenator and method and apparatus for making the same |
| US4735775A (en) * | 1984-02-27 | 1988-04-05 | Baxter Travenol Laboratories, Inc. | Mass transfer device having a heat-exchanger |
| US4572446A (en) * | 1984-03-23 | 1986-02-25 | Omnis Surgical Inc. | Process for making a fiber bundle |
| US4639353A (en) * | 1984-04-24 | 1987-01-27 | Mitsubishi Rayon Co., Ltd. | Blood oxygenator using a hollow-fiber membrane |
| US4690758A (en) * | 1984-11-05 | 1987-09-01 | Baxter Travenol Laboratories, Inc. | Mass transfer device |
| ZA8680B (en) * | 1985-01-08 | 1987-08-26 | Mcneilab Inc | Mass transfer device having a microporous,spirally wound hollow fiber membrane |
| JPH0775622B2 (ja) * | 1985-07-16 | 1995-08-16 | テルモ株式会社 | 人工肺用中空糸膜、その製造方法およびその中空糸膜を用いた人工肺 |
| IT1218450B (it) * | 1985-09-24 | 1990-04-19 | Teresa Borgione | Perfezionamenti agli ossigenatori per il sangue, a fibre cave |
| US4808378A (en) * | 1985-11-11 | 1989-02-28 | Senko Medical Instrument Mfg. Co., Ltd. | Blood oxygenator |
| US4722829A (en) * | 1986-03-24 | 1988-02-02 | Giter Gregory D | Blood oxygenator |
| US4876066A (en) * | 1986-07-14 | 1989-10-24 | Baxter International Inc. | Integrated membrane oxygenator, heat exchanger and reservoir |
| DE3803693A1 (de) * | 1987-03-10 | 1988-09-22 | Akzo Gmbh | Mehrlagiger hohlfadenwickelkoerper |
| IT1223470B (it) * | 1987-12-15 | 1990-09-19 | Dideco Spa | Unita' integrata in circuito extracorporeo di sangue |
| US5188801A (en) * | 1988-06-07 | 1993-02-23 | Cortek S.P.A. | Device for the treatment of blood |
| US5236665A (en) * | 1988-10-20 | 1993-08-17 | Baxter International Inc. | Hollow fiber treatment apparatus and membrane oxygenator |
| CA2001956A1 (en) * | 1988-12-14 | 1990-06-14 | Ronald J. Leonard | Membrane blood oxygenator |
| US5139741A (en) * | 1988-12-29 | 1992-08-18 | Terumo Kabushiki Kaisha | Blood processing apparatus of hollow fiber type |
| US5240677A (en) * | 1989-01-26 | 1993-08-31 | Shiley, Inc. | Hollow fiber blood oxygenator |
| US5316724A (en) * | 1989-03-31 | 1994-05-31 | Baxter International Inc. | Multiple blood path membrane oxygenator |
| DE4004797A1 (de) | 1990-02-16 | 1991-08-22 | Akzo Gmbh | Gewebtes hohlfadenband |
| SE502103C2 (sv) * | 1991-08-01 | 1995-08-14 | Gambro Dialysatoren | Filterenhet för överföring av massa och/eller värme innehållande hålrumsfibrer |
| US5263924A (en) * | 1991-09-25 | 1993-11-23 | Baxter International Inc. | Integrated low priming volume centrifugal pump and membrane oxygenator |
| US5266265A (en) * | 1992-10-08 | 1993-11-30 | Baxter International, Inc. | Modular disposable blood oxygenator/heat exchanger with durable heat source component, selectively including rotary or ventricular blood pump, venous reservoir, and auxiliary heat exchange component |
| EP0621047B1 (en) * | 1993-04-22 | 1996-12-11 | Cobe Laboratories, Inc. | Hollow fibre blood oxygenator |
| US5376334A (en) * | 1993-05-19 | 1994-12-27 | Avecor Cardiovascular Inc. | Mass transfer device having a hollow fiber bundle |
| US5346621A (en) * | 1993-05-19 | 1994-09-13 | Avecor Cardiovascular, Inc. | Hollow fiber blood oxygenator |
-
1994
- 1994-11-25 IT ITMI942403A patent/IT1271104B/it active IP Right Grant
-
1995
- 1995-11-20 US US08/560,625 patent/US5817278A/en not_active Expired - Lifetime
- 1995-11-22 ES ES95118373T patent/ES2161818T3/es not_active Expired - Lifetime
- 1995-11-22 AT AT95118373T patent/ATE205733T1/de not_active IP Right Cessation
- 1995-11-22 EP EP95118373A patent/EP0713709B1/en not_active Expired - Lifetime
- 1995-11-22 DE DE69522780T patent/DE69522780T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI942403A1 (it) | 1996-05-25 |
| ATE205733T1 (de) | 2001-10-15 |
| US5817278A (en) | 1998-10-06 |
| DE69522780D1 (de) | 2001-10-25 |
| EP0713709A2 (en) | 1996-05-29 |
| ITMI942403A0 (it) | 1994-11-25 |
| EP0713709A3 (en) | 1996-10-23 |
| EP0713709B1 (en) | 2001-09-19 |
| DE69522780T2 (de) | 2002-07-04 |
| ES2161818T3 (es) | 2001-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971126 |