JP6444406B2 - 高解像度スキャニング顕微鏡法 - Google Patents

高解像度スキャニング顕微鏡法 Download PDF

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Publication number
JP6444406B2
JP6444406B2 JP2016533862A JP2016533862A JP6444406B2 JP 6444406 B2 JP6444406 B2 JP 6444406B2 JP 2016533862 A JP2016533862 A JP 2016533862A JP 2016533862 A JP2016533862 A JP 2016533862A JP 6444406 B2 JP6444406 B2 JP 6444406B2
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detector
detector array
sample
fiber
individual
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Japanese (ja)
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JP2016532154A (ja
JP2016532154A5 (enExample
Inventor
クレッペ，インゴ
ノヴィカウ，ヤウヘン
ネッツ，ラルフ
ゲレス，ミヒャエル
ロレンツ，グンター
ニーテン，クリストフ
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Carl Zeiss Microscopy GmbH
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Carl Zeiss Microscopy GmbH
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0072—Optical details of the image generation details concerning resolution or correction, including general design of CSOM objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G02B21/025—Objectives with variable magnification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/18—Arrangements with more than one light path, e.g. for comparing two specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/361—Optical details, e.g. image relay to the camera or image sensor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/04—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres
    • G02B6/06—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres the relative position of the fibres being the same at both ends, e.g. for transporting images
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/0816—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light by means of one or more reflecting elements
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/0816—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light by means of one or more reflecting elements
    • G02B26/0825—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light by means of one or more reflecting elements the reflecting element being a flexible sheet or membrane, e.g. for varying the focus
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/0816—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light by means of one or more reflecting elements
    • G02B26/0833—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light by means of one or more reflecting elements the reflecting element being a micromechanical device, e.g. a MEMS mirror, DMD

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Multimedia (AREA)
  • Microscoopes, Condenser (AREA)
JP2016533862A 2013-08-15 2014-07-18 高解像度スキャニング顕微鏡法 Active JP6444406B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102013013793.4 2013-08-15
DE102013013793 2013-08-15
DE102013019348.6 2013-11-15
DE201310019348 DE102013019348A1 (de) 2013-08-15 2013-11-15 Hochauflösende Scanning-Mikroskopie
PCT/EP2014/065502 WO2015022147A1 (de) 2013-08-15 2014-07-18 Hochauflösende scanning-mikroskopie

Publications (3)

Publication Number Publication Date
JP2016532154A JP2016532154A (ja) 2016-10-13
JP2016532154A5 JP2016532154A5 (enExample) 2017-07-06
JP6444406B2 true JP6444406B2 (ja) 2018-12-26

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JP2016533862A Active JP6444406B2 (ja) 2013-08-15 2014-07-18 高解像度スキャニング顕微鏡法

Country Status (6)

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US (1) US10281701B2 (enExample)
EP (1) EP3033646B1 (enExample)
JP (1) JP6444406B2 (enExample)
CN (2) CN105612454A (enExample)
DE (1) DE102013019348A1 (enExample)
WO (1) WO2015022147A1 (enExample)

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DE102013015933A1 (de) * 2013-09-19 2015-03-19 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie
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DE102015100695B4 (de) * 2015-01-19 2024-10-31 Carl Zeiss Ag Optische Anordnung für ein Laser-Scanner-System
DE102015111702A1 (de) 2015-07-20 2017-01-26 Carl Zeiss Microscopy Gmbh Hochauflösende, spektral selektive Scanning-Mikroskopie einer Probe
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DE102016119262B4 (de) * 2016-10-10 2018-06-07 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum räumlich hochauflösenden Bestimmen des Orts eines vereinzelten, mit Anregungslicht zur Emission von Lumineszenzlicht anregbaren Moleküls in einer Probe
JP6784603B2 (ja) * 2017-01-05 2020-11-11 東レエンジニアリング株式会社 分光測定方法および分光測定装置
DE102017101829A1 (de) * 2017-01-31 2018-08-02 Carl Zeiss Microscopy Gmbh Anordnung zur Auflösungssteigerung eines Laser-Scanning-Mikroskops
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DE102017113683A1 (de) 2017-06-21 2018-12-27 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie mit der Unterscheidung mindestens zweier Wellenlängenbereiche
DE102017116982B4 (de) * 2017-07-27 2025-06-26 Coretronic Corporation Leuchteinrichtung zum abgeben von licht
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DE102017128773A1 (de) 2017-12-04 2019-06-06 Leica Microsystems Cms Gmbh Detektoranordnung für die Mikroskopie
WO2019133837A1 (en) * 2017-12-28 2019-07-04 University Of Notre Dame Du Lac Super-resolution fluorescence microscopy by stepwise optical saturation
EP3518017B1 (de) * 2018-01-24 2020-06-17 Technische Universität Dresden Verfahren und faseroptisches system zur beleuchtung und detektion eines objekts mit licht
DE102018127281A1 (de) * 2018-10-31 2020-04-30 Carl Zeiss Microscopy Gmbh Mikroskop und Verfahren zur Mikroskopie
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DE102020120114A1 (de) * 2020-07-30 2022-02-03 Abberior Instruments Gmbh Detektionseinrichtung für ein Laserscanning-Mikroskop
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WO2023114213A1 (en) * 2021-12-13 2023-06-22 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for multiplexed one-photon and nonlinear microscopy and method for biological tissue alignment
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Also Published As

Publication number Publication date
JP2016532154A (ja) 2016-10-13
CN108873285B (zh) 2020-11-24
DE102013019348A1 (de) 2015-02-19
EP3033646A1 (de) 2016-06-22
EP3033646B1 (de) 2024-09-25
US10281701B2 (en) 2019-05-07
WO2015022147A1 (de) 2015-02-19
CN105612454A (zh) 2016-05-25
CN108873285A (zh) 2018-11-23
US20150085099A1 (en) 2015-03-26

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