JP6438402B2 - O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法 - Google Patents
O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法 Download PDFInfo
- Publication number
- JP6438402B2 JP6438402B2 JP2015538462A JP2015538462A JP6438402B2 JP 6438402 B2 JP6438402 B2 JP 6438402B2 JP 2015538462 A JP2015538462 A JP 2015538462A JP 2015538462 A JP2015538462 A JP 2015538462A JP 6438402 B2 JP6438402 B2 JP 6438402B2
- Authority
- JP
- Japan
- Prior art keywords
- methionine
- amino acid
- homoserine
- seq
- phospho
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P11/00—Preparation of sulfur-containing organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
- C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01048—Cystathionine gamma-synthase (2.5.1.48)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12190150.8 | 2012-10-26 | ||
| EP12190150 | 2012-10-26 | ||
| PCT/EP2013/072380 WO2014064244A2 (en) | 2012-10-26 | 2013-10-25 | Means and methods for the enzymatic production of l-methionine from o-phospho-l-homoserine and methanethiol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015533280A JP2015533280A (ja) | 2015-11-24 |
| JP6438402B2 true JP6438402B2 (ja) | 2018-12-12 |
Family
ID=47071182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015538462A Active JP6438402B2 (ja) | 2012-10-26 | 2013-10-25 | O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9803225B2 (https=) |
| EP (1) | EP2912185A2 (https=) |
| JP (1) | JP6438402B2 (https=) |
| KR (1) | KR102126318B1 (https=) |
| CN (1) | CN104755625B (https=) |
| BR (1) | BR112015007212B1 (https=) |
| IN (1) | IN2015DN02439A (https=) |
| MY (1) | MY176164A (https=) |
| RU (1) | RU2650859C2 (https=) |
| WO (1) | WO2014064244A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10382927B2 (en) * | 2015-08-20 | 2019-08-13 | Samsung Electronics Co., Ltd. | Method of text input for wearable devices |
| EP3330380A1 (en) * | 2016-12-05 | 2018-06-06 | Evonik Degussa GmbH | Process for producing l-methionine from methional |
| WO2019011942A1 (en) | 2017-07-11 | 2019-01-17 | Adisseo France S.A.S. | YEAST PRODUCING METHIONINE |
| KR102025867B1 (ko) * | 2017-07-13 | 2019-09-27 | 씨제이제일제당 주식회사 | 인산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법 |
| JP6894650B2 (ja) * | 2018-10-30 | 2021-06-30 | GreenEarthInstitute株式会社 | 有機化合物の製造方法およびコリネ型細菌 |
| US20220315965A1 (en) * | 2019-06-25 | 2022-10-06 | Zymergen Inc. | Engineered biosynthetic pathways for production of cystathionine by fermentation |
| KR102744891B1 (ko) | 2022-03-24 | 2024-12-19 | 씨제이제일제당 주식회사 | 인산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법 |
| JP2026508194A (ja) * | 2023-03-01 | 2026-03-10 | フーナン リアー バイオテック カンパニー リミテッド | L-メチオニンをl-ホモセリンから直接調製するプロセス |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07503855A (ja) * | 1992-02-20 | 1995-04-27 | ジェネンコア インターナショナル インコーポレーテッド | 硫黄の還元源を用いたメチオニンの生合成 |
| WO2006082254A2 (en) * | 2005-02-07 | 2006-08-10 | Metabolic Explorer | Microorganisms comprising enzymes expressed with low gamma-elimination activity |
| CA2615416A1 (en) * | 2005-07-18 | 2007-01-25 | Basf Aktiengesellschaft | Methionine producing recombinant microorganisms |
| US8367392B2 (en) * | 2008-09-05 | 2013-02-05 | Transalgae Ltd. | Genetic transformation of algal and cyanobacteria cells by microporation |
-
2013
- 2013-10-25 JP JP2015538462A patent/JP6438402B2/ja active Active
- 2013-10-25 EP EP13792606.9A patent/EP2912185A2/en active Pending
- 2013-10-25 KR KR1020157009704A patent/KR102126318B1/ko active Active
- 2013-10-25 IN IN2439DEN2015 patent/IN2015DN02439A/en unknown
- 2013-10-25 MY MYPI2015000684A patent/MY176164A/en unknown
- 2013-10-25 RU RU2015119400A patent/RU2650859C2/ru active
- 2013-10-25 CN CN201380055160.XA patent/CN104755625B/zh active Active
- 2013-10-25 BR BR112015007212-7A patent/BR112015007212B1/pt active IP Right Grant
- 2013-10-25 US US14/438,847 patent/US9803225B2/en active Active
- 2013-10-25 WO PCT/EP2013/072380 patent/WO2014064244A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015007212A2 (pt) | 2018-01-30 |
| IN2015DN02439A (https=) | 2015-09-04 |
| BR112015007212B1 (pt) | 2022-07-05 |
| KR102126318B1 (ko) | 2020-06-25 |
| MY176164A (en) | 2020-07-24 |
| CN104755625A (zh) | 2015-07-01 |
| KR20150076159A (ko) | 2015-07-06 |
| WO2014064244A2 (en) | 2014-05-01 |
| JP2015533280A (ja) | 2015-11-24 |
| US9803225B2 (en) | 2017-10-31 |
| WO2014064244A3 (en) | 2014-08-14 |
| EP2912185A2 (en) | 2015-09-02 |
| RU2015119400A (ru) | 2016-12-20 |
| US20150275247A1 (en) | 2015-10-01 |
| RU2650859C2 (ru) | 2018-04-17 |
| CN104755625B (zh) | 2020-02-07 |
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