JP6433913B2 - アントラサイクリン製剤 - Google Patents

アントラサイクリン製剤 Download PDF

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Publication number
JP6433913B2
JP6433913B2 JP2015547985A JP2015547985A JP6433913B2 JP 6433913 B2 JP6433913 B2 JP 6433913B2 JP 2015547985 A JP2015547985 A JP 2015547985A JP 2015547985 A JP2015547985 A JP 2015547985A JP 6433913 B2 JP6433913 B2 JP 6433913B2
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JP
Japan
Prior art keywords
cancer
injectable composition
anthracycline compound
emch
doxo
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JP2015547985A
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English (en)
Japanese (ja)
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JP2016503026A5 (enExample
JP2016503026A (ja
Inventor
スコット ガイヤー，
スコット ガイヤー，
ダニエル レビット，
ダニエル レビット，
キャリー ノッドガード，
キャリー ノッドガード，
エドワード エイチ． トラッペラー，
エドワード エイチ． トラッペラー，
Original Assignee
サイトレックス コーポレイション
サイトレックス コーポレイション
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Publication of JP2016503026A5 publication Critical patent/JP2016503026A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2015547985A 2012-12-13 2013-12-13 アントラサイクリン製剤 Active JP6433913B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737003P 2012-12-13 2012-12-13
US61/737,003 2012-12-13
PCT/US2013/075002 WO2014093815A1 (en) 2012-12-13 2013-12-13 Anthracycline formulations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018145172A Division JP6833768B2 (ja) 2012-12-13 2018-08-01 アントラサイクリン製剤

Publications (3)

Publication Number Publication Date
JP2016503026A JP2016503026A (ja) 2016-02-01
JP2016503026A5 JP2016503026A5 (enExample) 2017-01-19
JP6433913B2 true JP6433913B2 (ja) 2018-12-05

Family

ID=50934989

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2015547985A Active JP6433913B2 (ja) 2012-12-13 2013-12-13 アントラサイクリン製剤
JP2018145172A Active JP6833768B2 (ja) 2012-12-13 2018-08-01 アントラサイクリン製剤
JP2019147584A Withdrawn JP2019206583A (ja) 2012-12-13 2019-08-09 アントラサイクリン製剤
JP2021085891A Active JP7213303B2 (ja) 2012-12-13 2021-05-21 アントラサイクリン製剤
JP2021085892A Pending JP2021120415A (ja) 2012-12-13 2021-05-21 アントラサイクリン製剤

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2018145172A Active JP6833768B2 (ja) 2012-12-13 2018-08-01 アントラサイクリン製剤
JP2019147584A Withdrawn JP2019206583A (ja) 2012-12-13 2019-08-09 アントラサイクリン製剤
JP2021085891A Active JP7213303B2 (ja) 2012-12-13 2021-05-21 アントラサイクリン製剤
JP2021085892A Pending JP2021120415A (ja) 2012-12-13 2021-05-21 アントラサイクリン製剤

Country Status (7)

Country Link
US (2) US20150342975A1 (enExample)
EP (2) EP2931042B1 (enExample)
JP (5) JP6433913B2 (enExample)
AU (1) AU2013359048A1 (enExample)
CA (1) CA2894548C (enExample)
DK (1) DK2931042T3 (enExample)
WO (1) WO2014093815A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021120414A (ja) * 2012-12-13 2021-08-19 サイトレックス コーポレイション アントラサイクリン製剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210059035A (ko) * 2013-06-05 2021-05-24 싸이트알엑스 코포레이션 암 치료용 세포독성제
RU2018106934A (ru) 2015-08-25 2019-09-26 Нантомикс, Ллс Системы и способы высокоточного определения вариантов
US11071812B2 (en) * 2016-05-31 2021-07-27 Penumbra, Inc. Methods and apparatus for extracting doxorubicin from blood and measuring doxorubicin in blood
JP7062754B2 (ja) 2017-08-15 2022-05-06 ナントセル，インコーポレイテッド ｈａＮＫセツキシマブ併用及び方法
WO2020081174A1 (en) 2018-10-16 2020-04-23 Nant Holdings Ip, Llc Alpha emitter compositions and methods

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426672D0 (en) 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
JP2915252B2 (ja) 1993-06-30 1999-07-05 明治製菓株式会社 溶解性が改善された製剤の製造法
NZ336381A (en) * 1996-12-30 2000-11-24 Battelle Memorial Institute Formulation and method for treating neoplasms by inhalation
DE19926154A1 (de) 1999-06-09 2000-12-14 Ktb Tumorforschungs Gmbh Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
DE10012120A1 (de) 2000-03-13 2001-09-27 Ktb Tumorforschungs Gmbh Therapeutische und diagnostische Ligandensysteme mit Transportmolekülbindenden Eigenschaften und diese enthaltende Arzneimittel
US6919370B2 (en) * 2000-11-28 2005-07-19 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
US20050148534A1 (en) * 2003-09-22 2005-07-07 Castellino Angelo J. Small molecule compositions and methods for increasing drug efficiency using compositions thereof
GB0621973D0 (en) * 2006-11-03 2006-12-13 Philogen Spa Binding molecules and uses thereof
MX2009012370A (es) 2007-05-16 2010-04-22 Ktb Tumorforschungs Gmbh Formulacion de antraciclina de baja viscosidad.
EP2216049A1 (en) * 2009-02-06 2010-08-11 Freie Universität Berlin Drug conjugates with polyglycerols
CA2740317A1 (en) * 2008-10-15 2010-04-22 Angiochem Inc. Etoposide and doxorubicin conjugates for drug delivery
EP2931042B1 (en) * 2012-12-13 2021-04-28 CytRx Corporation Anthracycline formulations

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021120414A (ja) * 2012-12-13 2021-08-19 サイトレックス コーポレイション アントラサイクリン製剤
JP7213303B2 (ja) 2012-12-13 2023-01-26 サイトレックス コーポレイション アントラサイクリン製剤

Also Published As

Publication number Publication date
AU2013359048A1 (en) 2015-07-02
JP2021120414A (ja) 2021-08-19
CA2894548A1 (en) 2014-06-19
JP2018165280A (ja) 2018-10-25
EP3915369A1 (en) 2021-12-01
JP2021120415A (ja) 2021-08-19
EP2931042A4 (en) 2016-06-01
US20150342975A1 (en) 2015-12-03
JP7213303B2 (ja) 2023-01-26
CA2894548C (en) 2021-01-12
US20170340655A1 (en) 2017-11-30
US10328093B2 (en) 2019-06-25
EP2931042A1 (en) 2015-10-21
JP2019206583A (ja) 2019-12-05
HK1209973A1 (en) 2016-04-15
WO2014093815A1 (en) 2014-06-19
JP6833768B2 (ja) 2021-02-24
JP2016503026A (ja) 2016-02-01
EP2931042B1 (en) 2021-04-28
DK2931042T3 (da) 2021-06-07

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