DK2931042T3 - Anthracyclinformuleringer - Google Patents

Anthracyclinformuleringer Download PDF

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Publication number
DK2931042T3
DK2931042T3 DK13863251.8T DK13863251T DK2931042T3 DK 2931042 T3 DK2931042 T3 DK 2931042T3 DK 13863251 T DK13863251 T DK 13863251T DK 2931042 T3 DK2931042 T3 DK 2931042T3
Authority
DK
Denmark
Prior art keywords
anthracycline
formulations
anthracycline formulations
Prior art date
Application number
DK13863251.8T
Other languages
Danish (da)
English (en)
Inventor
Scott Geyer
Daniel Levitt
Carrie Nodgaard
Edward H Trappler
Original Assignee
Cytrx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytrx Corp filed Critical Cytrx Corp
Application granted granted Critical
Publication of DK2931042T3 publication Critical patent/DK2931042T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK13863251.8T 2012-12-13 2013-12-13 Anthracyclinformuleringer DK2931042T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737003P 2012-12-13 2012-12-13
PCT/US2013/075002 WO2014093815A1 (en) 2012-12-13 2013-12-13 Anthracycline formulations

Publications (1)

Publication Number Publication Date
DK2931042T3 true DK2931042T3 (da) 2021-06-07

Family

ID=50934989

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13863251.8T DK2931042T3 (da) 2012-12-13 2013-12-13 Anthracyclinformuleringer

Country Status (7)

Country Link
US (2) US20150342975A1 (enExample)
EP (2) EP2931042B1 (enExample)
JP (5) JP6433913B2 (enExample)
AU (1) AU2013359048A1 (enExample)
CA (1) CA2894548C (enExample)
DK (1) DK2931042T3 (enExample)
WO (1) WO2014093815A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2931042B1 (en) * 2012-12-13 2021-04-28 CytRx Corporation Anthracycline formulations
KR20210059035A (ko) * 2013-06-05 2021-05-24 싸이트알엑스 코포레이션 암 치료용 세포독성제
RU2018106934A (ru) 2015-08-25 2019-09-26 Нантомикс, Ллс Системы и способы высокоточного определения вариантов
US11071812B2 (en) * 2016-05-31 2021-07-27 Penumbra, Inc. Methods and apparatus for extracting doxorubicin from blood and measuring doxorubicin in blood
JP7062754B2 (ja) 2017-08-15 2022-05-06 ナントセル,インコーポレイテッド haNKセツキシマブ併用及び方法
WO2020081174A1 (en) 2018-10-16 2020-04-23 Nant Holdings Ip, Llc Alpha emitter compositions and methods

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426672D0 (en) 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
JP2915252B2 (ja) 1993-06-30 1999-07-05 明治製菓株式会社 溶解性が改善された製剤の製造法
NZ336381A (en) * 1996-12-30 2000-11-24 Battelle Memorial Institute Formulation and method for treating neoplasms by inhalation
DE19926154A1 (de) 1999-06-09 2000-12-14 Ktb Tumorforschungs Gmbh Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
DE10012120A1 (de) 2000-03-13 2001-09-27 Ktb Tumorforschungs Gmbh Therapeutische und diagnostische Ligandensysteme mit Transportmolekülbindenden Eigenschaften und diese enthaltende Arzneimittel
US6919370B2 (en) * 2000-11-28 2005-07-19 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
US20050148534A1 (en) * 2003-09-22 2005-07-07 Castellino Angelo J. Small molecule compositions and methods for increasing drug efficiency using compositions thereof
GB0621973D0 (en) * 2006-11-03 2006-12-13 Philogen Spa Binding molecules and uses thereof
MX2009012370A (es) 2007-05-16 2010-04-22 Ktb Tumorforschungs Gmbh Formulacion de antraciclina de baja viscosidad.
EP2216049A1 (en) * 2009-02-06 2010-08-11 Freie Universität Berlin Drug conjugates with polyglycerols
CA2740317A1 (en) * 2008-10-15 2010-04-22 Angiochem Inc. Etoposide and doxorubicin conjugates for drug delivery
EP2931042B1 (en) * 2012-12-13 2021-04-28 CytRx Corporation Anthracycline formulations

Also Published As

Publication number Publication date
AU2013359048A1 (en) 2015-07-02
JP2021120414A (ja) 2021-08-19
CA2894548A1 (en) 2014-06-19
JP2018165280A (ja) 2018-10-25
JP6433913B2 (ja) 2018-12-05
EP3915369A1 (en) 2021-12-01
JP2021120415A (ja) 2021-08-19
EP2931042A4 (en) 2016-06-01
US20150342975A1 (en) 2015-12-03
JP7213303B2 (ja) 2023-01-26
CA2894548C (en) 2021-01-12
US20170340655A1 (en) 2017-11-30
US10328093B2 (en) 2019-06-25
EP2931042A1 (en) 2015-10-21
JP2019206583A (ja) 2019-12-05
HK1209973A1 (en) 2016-04-15
WO2014093815A1 (en) 2014-06-19
JP6833768B2 (ja) 2021-02-24
JP2016503026A (ja) 2016-02-01
EP2931042B1 (en) 2021-04-28

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