JP6431895B2 - 複合遺伝子セットにおいてユニークにタグ付けされた再構成された適応免疫受容体遺伝子 - Google Patents
複合遺伝子セットにおいてユニークにタグ付けされた再構成された適応免疫受容体遺伝子 Download PDFInfo
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- JP6431895B2 JP6431895B2 JP2016502574A JP2016502574A JP6431895B2 JP 6431895 B2 JP6431895 B2 JP 6431895B2 JP 2016502574 A JP2016502574 A JP 2016502574A JP 2016502574 A JP2016502574 A JP 2016502574A JP 6431895 B2 JP6431895 B2 JP 6431895B2
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- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361789408P | 2013-03-15 | 2013-03-15 | |
| US61/789,408 | 2013-03-15 | ||
| USPCT/US2013/045994 | 2013-06-14 | ||
| PCT/US2013/045994 WO2013188831A1 (en) | 2012-06-15 | 2013-06-14 | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
| PCT/US2014/030859 WO2014145992A1 (en) | 2013-03-15 | 2014-03-17 | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512685A JP2016512685A (ja) | 2016-05-09 |
| JP2016512685A5 JP2016512685A5 (OSRAM) | 2017-04-13 |
| JP6431895B2 true JP6431895B2 (ja) | 2018-12-05 |
Family
ID=51538155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502574A Active JP6431895B2 (ja) | 2013-03-15 | 2014-03-17 | 複合遺伝子セットにおいてユニークにタグ付けされた再構成された適応免疫受容体遺伝子 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20160024493A1 (OSRAM) |
| EP (1) | EP2971105B1 (OSRAM) |
| JP (1) | JP6431895B2 (OSRAM) |
| KR (1) | KR20150132479A (OSRAM) |
| CN (1) | CN105452483B (OSRAM) |
| AU (2) | AU2014232314B2 (OSRAM) |
| CA (1) | CA2906218A1 (OSRAM) |
| IL (1) | IL241394B (OSRAM) |
| SG (2) | SG11201506991VA (OSRAM) |
| WO (1) | WO2014145992A1 (OSRAM) |
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| US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
| EP3132059B1 (en) | 2014-04-17 | 2020-01-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US10202640B2 (en) * | 2014-05-07 | 2019-02-12 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing |
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| LT3892295T (lt) * | 2011-05-24 | 2023-07-10 | BioNTech SE | Individualizuotos vakcinos nuo vėžio |
| DK2823060T3 (en) * | 2012-03-05 | 2018-05-28 | Adaptive Biotechnologies Corp | Determination of associated immune receptor chains from frequency-matched subunits |
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| AU2014232314A1 (en) | 2015-09-17 |
| WO2014145992A1 (en) | 2014-09-18 |
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| CA2906218A1 (en) | 2014-09-18 |
| US20250043272A1 (en) | 2025-02-06 |
| CN105452483A (zh) | 2016-03-30 |
| SG10201707394PA (en) | 2017-10-30 |
| AU2020213348B2 (en) | 2022-05-19 |
| EP2971105B1 (en) | 2018-08-01 |
| IL241394A0 (en) | 2015-11-30 |
| KR20150132479A (ko) | 2015-11-25 |
| US20160024493A1 (en) | 2016-01-28 |
| CN105452483B (zh) | 2019-01-11 |
| AU2014232314B2 (en) | 2020-05-14 |
| JP2016512685A (ja) | 2016-05-09 |
| IL241394B (en) | 2019-12-31 |
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