JP6416627B2 - ペプチドおよびその使用法 - Google Patents

ペプチドおよびその使用法 Download PDF

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Publication number
JP6416627B2
JP6416627B2 JP2014551387A JP2014551387A JP6416627B2 JP 6416627 B2 JP6416627 B2 JP 6416627B2 JP 2014551387 A JP2014551387 A JP 2014551387A JP 2014551387 A JP2014551387 A JP 2014551387A JP 6416627 B2 JP6416627 B2 JP 6416627B2
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Prior art keywords
peptide
subject
peptides
amino acid
medicament
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Japanese (ja)
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JP2015504073A (ja
JP2015504073A5 (enExample
Inventor
ゾーレン モーゲルスヴァング
ゾーレン モーゲルスヴァング
コハバ ゲルバー
コハバ ゲルバー
Original Assignee
セルピン ファーマ リミテッド ライアビリティ カンパニー
セルピン ファーマ リミテッド ライアビリティ カンパニー
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Publication of JP2015504073A5 publication Critical patent/JP2015504073A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2014551387A 2012-01-09 2013-01-07 ペプチドおよびその使用法 Active JP6416627B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261584517P 2012-01-09 2012-01-09
US61/584,517 2012-01-09
US201261699571P 2012-09-11 2012-09-11
US61/699,571 2012-09-11
PCT/US2013/020498 WO2013106273A2 (en) 2012-01-09 2013-01-07 Peptides and methods of using same

Publications (3)

Publication Number Publication Date
JP2015504073A JP2015504073A (ja) 2015-02-05
JP2015504073A5 JP2015504073A5 (enExample) 2016-02-25
JP6416627B2 true JP6416627B2 (ja) 2018-10-31

Family

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JP2014551387A Active JP6416627B2 (ja) 2012-01-09 2013-01-07 ペプチドおよびその使用法

Country Status (10)

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US (6) US9951104B2 (enExample)
EP (2) EP2802338B1 (enExample)
JP (1) JP6416627B2 (enExample)
AU (3) AU2013208293B2 (enExample)
CA (2) CA3077804C (enExample)
DK (2) DK3381461T3 (enExample)
ES (2) ES2676028T3 (enExample)
IL (1) IL233481A0 (enExample)
MX (1) MX365403B (enExample)
WO (1) WO2013106273A2 (enExample)

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US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
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US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
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CA3004095A1 (en) * 2015-11-09 2017-05-18 Cortexyme, Inc. Inhibitors of arginine gingipain
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2019212031A1 (ja) * 2018-05-02 2019-11-07 国立大学法人新潟大学 ペプチド及びその使用
WO2022010939A2 (en) * 2020-07-06 2022-01-13 Serpin Pharma, Llc Peptides and methods of using the same

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Also Published As

Publication number Publication date
US20210188912A1 (en) 2021-06-24
ES2676028T3 (es) 2018-07-16
CA3077804C (en) 2023-07-25
IL233481A0 (en) 2014-08-31
US9951104B2 (en) 2018-04-24
US20170029465A9 (en) 2017-02-02
JP2015504073A (ja) 2015-02-05
DK2802338T3 (en) 2018-06-14
AU2017258892A1 (en) 2017-11-30
WO2013106273A2 (en) 2013-07-18
AU2019253814B2 (en) 2022-03-10
US20130274187A1 (en) 2013-10-17
AU2013208293B2 (en) 2017-08-10
US8975224B2 (en) 2015-03-10
EP3381461B1 (en) 2021-03-10
WO2013106273A3 (en) 2013-12-19
US20140378372A1 (en) 2014-12-25
CA2859777C (en) 2020-06-30
CA3077804A1 (en) 2013-07-18
AU2017258892B2 (en) 2019-11-14
EP2802338A2 (en) 2014-11-19
ES2871544T3 (es) 2021-10-29
CA2859777A1 (en) 2013-07-18
US20250346632A1 (en) 2025-11-13
AU2019253814A1 (en) 2019-11-14
US12291581B2 (en) 2025-05-06
DK3381461T3 (da) 2021-05-17
EP3381461A1 (en) 2018-10-03
US10214562B2 (en) 2019-02-26
US20200017550A1 (en) 2020-01-16
MX2014007799A (es) 2014-10-24
US10899797B2 (en) 2021-01-26
AU2013208293A2 (en) 2016-01-28
EP2802338B1 (en) 2018-03-07
US20150133375A1 (en) 2015-05-14
HK1203161A1 (en) 2015-10-23
AU2013208293A1 (en) 2014-06-26
BR112014016734A2 (pt) 2020-10-27
MX365403B (es) 2019-05-31

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