JP6408176B2 - 低プロファイル閉塞バルーンカテーテル用のシステムおよび方法 - Google Patents
低プロファイル閉塞バルーンカテーテル用のシステムおよび方法 Download PDFInfo
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- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
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- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
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Description
米国陸軍医療資材局による契約番号第W911QY−15−C−0099号に基づく政府支援により本発明を行った。米国政府は、本発明において一定の権利を有する。
あるいは、放射線不透過性先端部マーカー460は、図5の460’で示した非外傷性先端部450の最遠位位置に位置してもよい。バンドまたは平面状材料は、例えば、ステンレス鋼などの任意の好適な放射線不透過性材料、または白金イリジウムなどの好適な合金からなり得る。別の例示的な好ましい実施形態では、先端部450は、放射線不透過性材料で含浸させたプラスチックまたは例えばPEBAX等のポリエーテルブロックアミドなどのポリマーで作製されてもよい。別の好ましい例示的実施形態では、先端部450を形成するプラスチックまたはポリマー組成物は、例えばX線または蛍光透視法を使用して先端部450の視覚化を可能にするのに十分な硫酸バリウムなどの放射線不透過性化合物と混合されてもよい。閉塞カテーテルシステム10の第1の好ましい実施形態を含む、本明細書に記載した閉塞カテーテルシステム10の好ましい実施形態のいずれかは、大血管VW、好ましくは患者の大動脈内にカテーテルシステム10を誘導すること、およびカテーテル12が挿入中に二次的血管VWに入るのを概ね防ぐことを促進するように閉塞カテーテルシステム10の遠位端12c上に取り付けられ、または共成形された非外傷性先端部450を含むことができる。
Claims (26)
- 内面を有する血管の閉塞または部分閉塞のための閉塞カテーテルシステムであって、前記閉塞カテーテルシステムは、
補剛部材、第1の膨張用内腔、カテーテル近位端、およびカテーテル遠位端を有する膨張カテーテル部材であって、長手方向軸を画定し、前記カテーテル遠位端に非外傷性先端部を有する、膨張カテーテル部材と、
バルーン内部空間、バルーン外表面、バルーン近位端、およびバルーン遠位端を有する閉塞バルーンであって、前記バルーン近位端および前記バルーン遠位端が前記カテーテル近位端と前記カテーテル遠位端との間で前記膨張カテーテル部材に接続され、前記閉塞バルーンが膨張した形態で前記長手方向軸に沿って実質的に中心に置かれ、前記第1の膨張用内腔が前記バルーン内部空間と流体連通する、閉塞バルーンと、
前記バルーン遠位端と前記非外傷性先端部との間で前記膨張カテーテル部材に取り付けられた遠位圧力センサと、
スパイン内部空間、スパイン外表面、スパイン近位端、およびスパイン遠位端を有する膨張可能スパインであって、前記スパイン近位端および前記スパイン遠位端が前記膨張カテーテル部材に接続され、前記閉塞バルーンおよび前記膨張可能スパインが膨張した形態であるとき、前記バルーン外表面の一部分が前記スパイン外表面と接触し、前記スパイン近位端が前記バルーン近位端の近くで前記膨張カテーテル部材に接続され、前記スパイン遠位端が前記バルーン遠位端の近くで前記膨張カテーテル部材に接続され、前記閉塞カテーテルシステムが前記血管内に少なくとも部分的に位置決めされ、および前記閉塞バルーンおよび前記膨張可能スパインが部分的に膨張した形態であるとき、前記閉塞バルーンおよび前記膨張可能スパインが前記内面および前記バルーン外表面で血液流路を画定するように構成される、膨張可能スパインと、
を備える閉塞カテーテルシステム。 - 前記膨張可能スパインは、部分的に膨張した形態および完全に膨張した形態で前記スパイン近位端と前記スパイン遠位端との間にほぼ一定のスパイン直径を有する、請求項1に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンは、閉塞直径を有し、前記閉塞直径は、前記閉塞バルーンおよび前記膨張可能スパインが部分的膨張圧力で膨張したとき、前記スパイン直径の少なくとも2倍である、請求項2に記載の閉塞カテーテルシステム。
- 前記第1の膨張用内腔は、前記膨張可能スパインと流体連通する、請求項1に記載の閉塞カテーテルシステム。
- 前記膨張カテーテル部材は、第2の膨張用内腔を含み、前記第2の膨張用内腔は、前記膨張可能スパインと流体連通する、請求項1に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンは、適合した高分子材料で構築され、前記膨張可能スパインは、不適合材料で構築される、請求項1に記載の閉塞カテーテルシステム。
- 前記遠位圧力センサは、電子圧力センサからなる、請求項1に記載の閉塞カテーテルシステム。
- 前記遠位圧力センサは、前記膨張カテーテル部材内の遠位側ポートからなり、前記補剛部材は、内部に内腔を含み、前記遠位側ポートは、前記補剛部材内の前記内腔と流体連通する、請求項1に記載の閉塞カテーテルシステム。
- 前記補剛部材は、ハイポチューブからなり、前記内腔は、ハイポチューブ内腔からなる、請求項8に記載の閉塞カテーテルシステム。
- 前記ハイポチューブは、ニチノール材料で構築される、請求項9に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンおよび前記膨張可能スパインは、前記閉塞バルーンが完全に膨張した形態で前記内面に対して前記膨張可能スパインを過駆動させ、実質的に平坦化するように構成される、請求項1に記載の閉塞カテーテルシステム。
- 前記非外傷性先端部は、2つの概ね平坦な対向面を有する概ね平坦化した円筒からなる、請求項1に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンに対して近位に前記膨張カテーテル部材に取り付けられた近位圧力センサを更に備える、
請求項1に記載の閉塞カテーテルシステム。 - 前記近位圧力センサおよび前記遠位圧力センサと通信するコントローラと、
前記閉塞バルーンおよび前記膨張可能スパインと流体連通するポンプであって、前記コントローラが前記近位圧力センサおよび前記遠位圧力センサからの圧力測定値に基づいて、前記閉塞バルーンおよび前記膨張可能スパイン内に加圧流体を導入すること、ならびに前記閉塞バルーンおよび前記膨張可能スパインから流体を取り出すことのうちの1つを行うように構成される、ポンプと、
を更に備える、請求項13に記載の閉塞カテーテルシステム。 - 前記カテーテル近位端の近くで前記膨張カテーテル部材に取付可能な制御ハブであって、表示画面および電源を含み、前記遠位圧力センサからの圧力を前記表示画面に示すように構成される、制御ハブを更に備える、
請求項1に記載の閉塞カテーテルシステム。 - 内面を有する血管の閉塞または部分閉塞のための閉塞カテーテルシステムであって、前記閉塞カテーテルシステムは、
補剛部材、第1の膨張用内腔、第2の膨張用内腔、カテーテル近位端、およびカテーテル遠位端を有する膨張カテーテル部材であって、長手方向軸を画定し、前記カテーテル遠位端に非外傷性先端部を有する、膨張カテーテル部材と、
バルーン内部空間、バルーン外表面、バルーン近位端、およびバルーン遠位端を有する閉塞バルーンであって、前記バルーン近位端および前記バルーン遠位端が前記カテーテル近位端と前記カテーテル遠位端との間で前記膨張カテーテル部材に接続され、前記閉塞バルーンが膨張した形態で前記長手方向軸に沿って実質的に中心に置かれ、前記第1の膨張用内腔が前記バルーン内部空間と流体連通する、閉塞バルーンと、
前記バルーン近位端と前記非外傷性先端部との間で前記膨張カテーテル部材に取り付けられた遠位圧力センサと、
スパイン内部空間、スパイン外表面、スパイン近位端、およびスパイン遠位端を有する膨張可能スパインであって、前記スパイン近位端および前記スパイン遠位端が前記膨張カテーテル部材に接続され、前記スパイン内部空間が前記第2の膨張用内腔と流体連通し、前記閉塞バルーンおよび前記膨張可能スパインが膨張した形態であるとき、前記バルーン外表面の一部分が前記スパイン外表面と接触し、前記スパイン近位端が前記バルーン近位端の近くで前記膨張カテーテル部材に接続され、前記スパイン遠位端が前記バルーン遠位端の近くで前記膨張カテーテル部材に接続される、膨張可能スパインと、
を備える閉塞カテーテルシステム。 - 前記閉塞バルーンは、適合した高分子材料で構築され、前記膨張可能スパインは、不適合材料で構築される、請求項16に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンは、適合した第1のポリウレタン材料で構築され、前記膨張可能スパインは、不適合の第2のポリウレタン材料で構築され、前記第1のポリウレタン材料は、第1のデュロメータを有し、前記第2のポリウレタン材料は、第2のデュロメータを有し、前記第2のデュロメータは、前記第1のデュロメータより高い、請求項17に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンおよび前記膨張可能スパインは、前記閉塞カテーテルシステムが前記血管内に少なくとも部分的に位置決めされ、および前記閉塞バルーンおよび前記膨張可能スパインが部分的に膨張した形態であるとき、前記内面および前記バルーン外表面で血液流路を画定するように構成される、請求項16に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンおよび前記膨張可能スパインは、前記閉塞バルーンが完全に膨張した形態で前記内面に対して前記膨張可能スパインを過駆動させ、実質的に平坦化するように構成される、請求項16に記載の閉塞カテーテルシステム。
- 前記膨張カテーテル部材は、実質的に同軸方向に延在し、および前記長手方向軸を実質的に画定する補剛部材を含む、請求項16に記載の閉塞カテーテルシステム。
- 前記補剛部材は、ハイポチューブからなる、請求項21に記載の閉塞カテーテルシステム。
- 前記遠位圧力センサは、電子圧力センサからなる、請求項16に記載の閉塞カテーテルシステム。
- 前記閉塞バルーンに対して近位に前記膨張カテーテル部材に取り付けられた近位圧力センサを更に備える、
請求項16に記載の閉塞カテーテルシステム。 - 前記近位圧力センサおよび前記遠位圧力センサと通信するコントローラと、
前記閉塞バルーンおよび前記膨張可能スパインと流体連通するポンプであって、前記コントローラが前記近位圧力センサおよび前記遠位圧力センサからの圧力測定値に基づいて、前記閉塞バルーンおよび前記膨張可能スパイン内に加圧流体を導入すること、ならびに前記閉塞バルーンおよび前記膨張可能スパインから流体を取り出すことのうちの1つを行うように構成される、ポンプと、
を更に備える、請求項24に記載の閉塞カテーテルシステム。 - 前記カテーテル近位端の近くで前記膨張カテーテル部材に取付可能な制御ハブであって、表示画面および電源を含み、前記遠位圧力センサからの圧力を前記表示画面に示すように構成される、制御ハブを更に備える、
請求項16に記載の閉塞カテーテルシステム。
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US11602592B2 (en) | 2017-01-12 | 2023-03-14 | The Regents Of The University Of California | Endovascular perfusion augmentation for critical care |
US11596411B2 (en) | 2017-04-21 | 2023-03-07 | The Regents Of The University Of California | Aortic flow meter and pump for partial-aortic occlusion |
US11633192B2 (en) | 2020-03-16 | 2023-04-25 | Certus Critical Care, Inc. | Blood flow control devices, systems, and methods |
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CA3012017A1 (en) | 2017-12-07 |
EP3463106A4 (en) | 2019-06-12 |
EP3463106A1 (en) | 2019-04-10 |
JP2019048059A (ja) | 2019-03-28 |
AU2017272335B2 (en) | 2018-06-14 |
EP4302815A2 (en) | 2024-01-10 |
AU2017272335A1 (en) | 2018-01-25 |
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US11253264B2 (en) | 2022-02-22 |
WO2017210584A1 (en) | 2017-12-07 |
CA2990479C (en) | 2019-03-26 |
JP2018523506A (ja) | 2018-08-23 |
AU2018203640A1 (en) | 2018-06-14 |
US20190076152A1 (en) | 2019-03-14 |
US20220323083A1 (en) | 2022-10-13 |
CA2990479A1 (en) | 2017-12-07 |
IL258255A (en) | 2018-05-31 |
EP4302815A3 (en) | 2024-03-27 |
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