JP6393186B2 - 免疫療法を用いたil−12の誘導 - Google Patents
免疫療法を用いたil−12の誘導 Download PDFInfo
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- JP6393186B2 JP6393186B2 JP2014509386A JP2014509386A JP6393186B2 JP 6393186 B2 JP6393186 B2 JP 6393186B2 JP 2014509386 A JP2014509386 A JP 2014509386A JP 2014509386 A JP2014509386 A JP 2014509386A JP 6393186 B2 JP6393186 B2 JP 6393186B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161482009P | 2011-05-03 | 2011-05-03 | |
| US61/482,009 | 2011-05-03 | ||
| US201161528484P | 2011-08-29 | 2011-08-29 | |
| US61/528,484 | 2011-08-29 | ||
| US201161564551P | 2011-11-29 | 2011-11-29 | |
| US61/564,551 | 2011-11-29 | ||
| US201261582881P | 2012-01-04 | 2012-01-04 | |
| US61/582,881 | 2012-01-04 | ||
| PCT/US2012/036123 WO2012151279A2 (en) | 2011-05-03 | 2012-05-02 | Induction of il-12 using immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017079200A Division JP6615148B2 (ja) | 2011-05-03 | 2017-04-12 | 免疫療法を用いたil−12の誘導 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014513126A JP2014513126A (ja) | 2014-05-29 |
| JP2014513126A5 JP2014513126A5 (enExample) | 2015-06-25 |
| JP6393186B2 true JP6393186B2 (ja) | 2018-09-19 |
Family
ID=47108207
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014509386A Active JP6393186B2 (ja) | 2011-05-03 | 2012-05-02 | 免疫療法を用いたil−12の誘導 |
| JP2017079200A Active JP6615148B2 (ja) | 2011-05-03 | 2017-04-12 | 免疫療法を用いたil−12の誘導 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017079200A Active JP6615148B2 (ja) | 2011-05-03 | 2017-04-12 | 免疫療法を用いたil−12の誘導 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9233156B2 (enExample) |
| EP (1) | EP2704732B1 (enExample) |
| JP (2) | JP6393186B2 (enExample) |
| KR (1) | KR102121492B1 (enExample) |
| CN (2) | CN109876138A (enExample) |
| AU (3) | AU2012250807A1 (enExample) |
| BR (1) | BR112013028285A2 (enExample) |
| CA (1) | CA2838046C (enExample) |
| IL (1) | IL229177B (enExample) |
| PH (1) | PH12013502252B1 (enExample) |
| SG (2) | SG10201901391RA (enExample) |
| WO (1) | WO2012151279A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017141287A (ja) * | 2011-05-03 | 2017-08-17 | イミュノバティブ セラピーズ,リミテッド | 免疫療法を用いたil−12の誘導 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX390311B (es) | 2013-12-05 | 2025-03-20 | Rfemb Holdings Llc | Presentacion de antigeno de cancer mejorado a celulas que presentan por la descomposicion electrica de membrana por radiofrecuencia (rf-rmb) como un mecanismo adyuvante para la inmunoterapia. |
| JP6202339B2 (ja) * | 2013-12-19 | 2017-09-27 | 国立研究開発法人国立精神・神経医療研究センター | GM−CSF産生T細胞制御剤、及びTh1/Th2免疫バランス調節剤 |
| CA2975123A1 (en) | 2015-01-30 | 2016-08-04 | Rfemb Holdings, Llc | Radio frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue |
| TW202428236A (zh) * | 2016-01-15 | 2024-07-16 | 美商Rfemb控股有限公司 | 癌症之免疫治療 |
| JP2020528077A (ja) * | 2017-07-14 | 2020-09-17 | ミンジェン シュー, | M1優位の免疫応答を誘導するための方法および薬学的組成物 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
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| FR2439003A1 (fr) | 1978-10-20 | 1980-05-16 | Anvar | Nouvelles pieces d'osteosynthese, leur preparation et leur application |
| US5766920A (en) | 1982-08-11 | 1998-06-16 | Cellcor, Inc. | Ex vivo activation of immune cells |
| AU7873187A (en) | 1986-08-08 | 1988-02-24 | University Of Minnesota | Method of culturing leukocytes |
| ZA888978B (en) | 1987-12-04 | 1990-07-25 | Du Pont | Immobilized interleukin 2 and interleukin 2 containing a carboxylterminal extension |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5126132A (en) | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| US5728388A (en) | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| JPH0455577A (ja) | 1990-06-22 | 1992-02-24 | Mitsubishi Electric Corp | 構造物の制振装置 |
| WO1994012196A1 (en) | 1992-11-25 | 1994-06-09 | Tanox Biosystems, Inc. | Conjugates and constructs including anti-cd28 and anti-cd3 binding molecules |
| AU7478394A (en) | 1993-08-06 | 1995-02-28 | Cytel Corporation | Methods for (ex vivo) therapy using peptide-loaded antigen presenting cells for the activation of ctl |
| IL107483A0 (en) | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| ES2201177T3 (es) | 1995-03-08 | 2004-03-16 | The Scripps Research Institute | Sistema de presentacion de antigenos y activacion de celulas-t. |
| DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| JPH09255577A (ja) * | 1996-03-27 | 1997-09-30 | Dainippon Ink & Chem Inc | インターリュウキン−12誘導剤 |
| CA2254975C (en) | 1996-05-23 | 2008-12-16 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
| CA2274004A1 (en) | 1996-12-03 | 1998-06-11 | Osteobiologics, Inc. | Biodegradable polymeric film |
| WO1998033891A1 (en) | 1997-01-31 | 1998-08-06 | Hemosol Inc. | Method for the production of selected lymphocytes |
| DE69840171D1 (de) | 1997-05-30 | 2008-12-11 | Osteobiologics Inc | Faserverstärkte,poröse,biologisch abbaubare implantatvorrichtung |
| JP2001522806A (ja) | 1997-11-10 | 2001-11-20 | アーチ・デヴェロップメント・コーポレイション | エクス・ビボ活性化t細胞を用いる腫瘍および腫瘍細胞の処理方法 |
| JP2001054563A (ja) | 1999-07-12 | 2001-02-27 | Isotis Bv | 縫合糸 |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US20030119185A1 (en) | 2000-02-24 | 2003-06-26 | Xcyte Therapies, Inc. | Activation and expansion of cells |
| DK1257632T3 (da) | 2000-02-24 | 2008-01-28 | Xcyte Therapies Inc | Samtidig stimulering og opkoncentrering af celler |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017141287A (ja) * | 2011-05-03 | 2017-08-17 | イミュノバティブ セラピーズ,リミテッド | 免疫療法を用いたil−12の誘導 |
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013028285A2 (pt) | 2017-01-10 |
| KR102121492B1 (ko) | 2020-06-11 |
| IL229177B (en) | 2020-07-30 |
| US11883490B2 (en) | 2024-01-30 |
| JP6615148B2 (ja) | 2019-12-04 |
| EP2704732A2 (en) | 2014-03-12 |
| SG10201901391RA (en) | 2019-03-28 |
| JP2014513126A (ja) | 2014-05-29 |
| AU2019204699A1 (en) | 2019-07-18 |
| CA2838046C (en) | 2023-03-07 |
| CN109876138A (zh) | 2019-06-14 |
| EP2704732B1 (en) | 2020-03-04 |
| US20160089433A1 (en) | 2016-03-31 |
| AU2012250807A1 (en) | 2013-12-12 |
| CA2838046A1 (en) | 2012-11-08 |
| PH12013502252A1 (en) | 2014-01-06 |
| WO2012151279A3 (en) | 2012-12-20 |
| US20210268106A1 (en) | 2021-09-02 |
| US11045541B2 (en) | 2021-06-29 |
| CN103687602A (zh) | 2014-03-26 |
| EP2704732A4 (en) | 2015-02-25 |
| JP2017141287A (ja) | 2017-08-17 |
| US20240148865A1 (en) | 2024-05-09 |
| US20130101551A1 (en) | 2013-04-25 |
| AU2017204058A1 (en) | 2017-07-13 |
| WO2012151279A2 (en) | 2012-11-08 |
| PH12013502252B1 (en) | 2018-09-21 |
| KR20140041517A (ko) | 2014-04-04 |
| IL229177A0 (en) | 2013-12-31 |
| SG194753A1 (en) | 2013-12-30 |
| US9233156B2 (en) | 2016-01-12 |
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