SG10201901391RA - Induction of il-12 using immunotherapy - Google Patents
Induction of il-12 using immunotherapyInfo
- Publication number
- SG10201901391RA SG10201901391RA SG10201901391RA SG10201901391RA SG10201901391RA SG 10201901391R A SG10201901391R A SG 10201901391RA SG 10201901391R A SG10201901391R A SG 10201901391RA SG 10201901391R A SG10201901391R A SG 10201901391RA SG 10201901391R A SG10201901391R A SG 10201901391RA
- Authority
- SG
- Singapore
- Prior art keywords
- patient
- induction
- immunotherapy
- composition
- skews
- Prior art date
Links
- 230000006698 induction Effects 0.000 title abstract 3
- 238000009169 immunotherapy Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
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Abstract
INDUCTION OF IL-12 USING IMMUNOTHERAPY The present invention relates to compositions and methods that promote the induction of IL-12 in a patient. The composition includes activated allogeneic cells that are administered to a patient with a disease such as cancer. Administration of the composition skews the patient's immune response to a Thl environment and produces detectable levels of IL-12 in the patient's plasma, without any IL-12 related toxicity. (FIGURE 1)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161482009P | 2011-05-03 | 2011-05-03 | |
US201161528484P | 2011-08-29 | 2011-08-29 | |
US201161564551P | 2011-11-29 | 2011-11-29 | |
US201261582881P | 2012-01-04 | 2012-01-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201901391RA true SG10201901391RA (en) | 2019-03-28 |
Family
ID=47108207
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201901391RA SG10201901391RA (en) | 2011-05-03 | 2012-05-02 | Induction of il-12 using immunotherapy |
SG2013081302A SG194753A1 (en) | 2011-05-03 | 2012-05-02 | Induction of il-12 using immunotherapy |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2013081302A SG194753A1 (en) | 2011-05-03 | 2012-05-02 | Induction of il-12 using immunotherapy |
Country Status (11)
Country | Link |
---|---|
US (3) | US9233156B2 (en) |
EP (1) | EP2704732B1 (en) |
JP (2) | JP6393186B2 (en) |
KR (1) | KR102121492B1 (en) |
CN (2) | CN103687602A (en) |
AU (3) | AU2012250807A1 (en) |
BR (1) | BR112013028285A2 (en) |
CA (1) | CA2838046C (en) |
IL (1) | IL229177B (en) |
SG (2) | SG10201901391RA (en) |
WO (1) | WO2012151279A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG10201901391RA (en) | 2011-05-03 | 2019-03-28 | Immunovative Therapies Ltd | Induction of il-12 using immunotherapy |
CN111167008A (en) | 2013-12-05 | 2020-05-19 | 免疫系统公司 | Cancer immunotherapy with radiofrequency electrical membrane breakdown (RF-EMB) |
JP6202339B2 (en) * | 2013-12-19 | 2017-09-27 | 国立研究開発法人国立精神・神経医療研究センター | GM-CSF producing T cell regulator and Th1 / Th2 immune balance regulator |
WO2016123608A2 (en) | 2015-01-30 | 2016-08-04 | Rfemb Holdings, Llc | Radio-frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue |
CN109069624A (en) | 2016-01-15 | 2018-12-21 | 瑞美控股有限责任公司 | The immunization therapy of cancer |
JP2020528077A (en) * | 2017-07-14 | 2020-09-17 | ミンジェン シュー, | Methods and Pharmaceutical Compositions for Inducing M1-Predominant Immune Responses |
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HUE035726T2 (en) * | 2004-03-01 | 2018-05-28 | Immunovative Therapies Ltd | Cell therapy formulation method and composition |
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SG10201901391RA (en) * | 2011-05-03 | 2019-03-28 | Immunovative Therapies Ltd | Induction of il-12 using immunotherapy |
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2012
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SG194753A1 (en) | 2013-12-30 |
JP6615148B2 (en) | 2019-12-04 |
US20210268106A1 (en) | 2021-09-02 |
KR20140041517A (en) | 2014-04-04 |
CN109876138A (en) | 2019-06-14 |
EP2704732B1 (en) | 2020-03-04 |
US20160089433A1 (en) | 2016-03-31 |
CN103687602A (en) | 2014-03-26 |
US20130101551A1 (en) | 2013-04-25 |
WO2012151279A3 (en) | 2012-12-20 |
US11045541B2 (en) | 2021-06-29 |
KR102121492B1 (en) | 2020-06-11 |
JP2017141287A (en) | 2017-08-17 |
CA2838046C (en) | 2023-03-07 |
EP2704732A2 (en) | 2014-03-12 |
US9233156B2 (en) | 2016-01-12 |
EP2704732A4 (en) | 2015-02-25 |
IL229177A0 (en) | 2013-12-31 |
JP2014513126A (en) | 2014-05-29 |
JP6393186B2 (en) | 2018-09-19 |
CA2838046A1 (en) | 2012-11-08 |
AU2019204699A1 (en) | 2019-07-18 |
AU2012250807A1 (en) | 2013-12-12 |
US11883490B2 (en) | 2024-01-30 |
IL229177B (en) | 2020-07-30 |
AU2017204058A1 (en) | 2017-07-13 |
WO2012151279A2 (en) | 2012-11-08 |
BR112013028285A2 (en) | 2017-01-10 |
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