JP6388283B2 - スタチン治療を受けていない冠動脈疾患患者の心血管転帰を予測するためのリピドミックバイオマーカー - Google Patents

スタチン治療を受けていない冠動脈疾患患者の心血管転帰を予測するためのリピドミックバイオマーカー Download PDF

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JP6388283B2
JP6388283B2 JP2014540426A JP2014540426A JP6388283B2 JP 6388283 B2 JP6388283 B2 JP 6388283B2 JP 2014540426 A JP2014540426 A JP 2014540426A JP 2014540426 A JP2014540426 A JP 2014540426A JP 6388283 B2 JP6388283 B2 JP 6388283B2
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cer
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JP2014532885A5 (cg-RX-API-DMAC7.html
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レイヨ ラークソネン
レイヨ ラークソネン
キム エクロース
キム エクロース
レイニ フルメ
レイニ フルメ
ミンナ ヤニス
ミンナ ヤニス
リイッカ カタイネン
リイッカ カタイネン
キリル タラソフ
キリル タラソフ
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ゾラ バイオサイエンシーズ オサケ ユキチュア
ゾラ バイオサイエンシーズ オサケ ユキチュア
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
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  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2014540426A 2011-11-08 2012-11-07 スタチン治療を受けていない冠動脈疾患患者の心血管転帰を予測するためのリピドミックバイオマーカー Active JP6388283B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161556909P 2011-11-08 2011-11-08
US61/556,909 2011-11-08
EP11188328.6A EP2592423A1 (en) 2011-11-08 2011-11-08 Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment
EP11188328.6 2011-11-08
PCT/EP2012/071972 WO2013068373A2 (en) 2011-11-08 2012-11-07 Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment

Publications (3)

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JP2014532885A JP2014532885A (ja) 2014-12-08
JP2014532885A5 JP2014532885A5 (cg-RX-API-DMAC7.html) 2016-03-24
JP6388283B2 true JP6388283B2 (ja) 2018-09-12

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JP2014540426A Active JP6388283B2 (ja) 2011-11-08 2012-11-07 スタチン治療を受けていない冠動脈疾患患者の心血管転帰を予測するためのリピドミックバイオマーカー

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US (3) US9052328B2 (cg-RX-API-DMAC7.html)
EP (3) EP2592423A1 (cg-RX-API-DMAC7.html)
JP (1) JP6388283B2 (cg-RX-API-DMAC7.html)
CN (1) CN103917876B (cg-RX-API-DMAC7.html)
CA (1) CA2853220A1 (cg-RX-API-DMAC7.html)
HK (1) HK1202157A1 (cg-RX-API-DMAC7.html)
WO (1) WO2013068373A2 (cg-RX-API-DMAC7.html)

Cited By (1)

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KR20210100679A (ko) * 2018-12-06 2021-08-17 조라 바이오사이언시즈 오와이 심혈관계 이벤트용 바이오마커

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EP2592423A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment
ES2552371T3 (es) * 2012-05-25 2015-11-27 Zora Biosciences Oy Biomarcadores sensibles, eficaces e inocuos, para la inhibición de la Proproteína Convertasa Subtilisina/Kexina de tipo 9 (PCSK9)
CN105723223B (zh) * 2013-11-14 2019-04-09 雀巢产品技术援助有限公司 预测健康衰老的脂质生物标志物
NZ724790A (en) 2014-04-10 2022-07-29 MEP Equine Solutions LLC Method for the quantification of parasite eggs in feces
US9347960B2 (en) 2014-06-16 2016-05-24 Zora Biosciences, Oy Ceramides and their use in diagnosing CVD
EP3177939A1 (en) 2014-09-11 2017-06-14 Liposcience, Inc. Cardiovascular risk evaluations using a risk parameter that includes an hdl and inflammatory biomarker interaction parameter
WO2016100549A2 (en) 2014-12-16 2016-06-23 Washington University Ceramides for evaluating risk of cardiovascular disease
US20180238914A1 (en) * 2015-08-19 2018-08-23 Metanomics Gmbh Means and methods for diagnosing cardiac disease in a subject
ES2861401T3 (es) * 2015-10-20 2021-10-06 Medimmune Llc Marcador de diagnóstico para arteriopatía coronaria
WO2017097852A2 (en) 2015-12-07 2017-06-15 Zora Biosciences Oy Use of ceramides and lpls in diagnosing cvd
CN105424841B (zh) * 2015-12-25 2017-11-03 齐炼文 用于诊断冠状动脉粥样硬化的代谢标志物
CN107014942A (zh) * 2017-05-05 2017-08-04 北京骐骥生物技术有限公司 利用脂质生物标志物预测糖尿病冠心病的方法
CN107144624B (zh) * 2017-05-15 2021-01-05 中国科学院生态环境研究中心 甄别二氧化硅颗粒来源的方法
CN114062581A (zh) * 2017-12-14 2022-02-18 江苏豪思生物科技有限公司 一种用于评估冠状动脉疾病的试剂盒
WO2019119049A1 (en) * 2017-12-20 2019-06-27 Baker Heart and Diabetes Institute Method of predicting drug therapeutic responder status and methods of treatment
CN113533754A (zh) * 2021-07-12 2021-10-22 北京市心肺血管疾病研究所 神经酰胺在制备用于评估高血压患者发生不良事件风险的试剂盒中的应用
WO2024192471A1 (en) * 2023-03-20 2024-09-26 Baker Heart and Diabetes Institute Methods of assessing metabolic health

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EP2592422A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment
EP2592423A1 (en) 2011-11-08 2013-05-15 Zora Biosciences OY Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210100679A (ko) * 2018-12-06 2021-08-17 조라 바이오사이언시즈 오와이 심혈관계 이벤트용 바이오마커
KR102897948B1 (ko) * 2018-12-06 2025-12-09 조라 바이오사이언시즈 오와이 심혈관계 이벤트용 바이오마커

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CA2853220A1 (en) 2013-05-16
EP2592423A1 (en) 2013-05-15
US9423406B2 (en) 2016-08-23
JP2014532885A (ja) 2014-12-08
WO2013068373A3 (en) 2013-07-18
US20160320418A1 (en) 2016-11-03
US9052328B2 (en) 2015-06-09
HK1202157A1 (en) 2015-09-18
US20150260737A1 (en) 2015-09-17
EP2776841B1 (en) 2017-01-11
EP3208617A3 (en) 2017-11-01
CN103917876A (zh) 2014-07-09
EP2776841A2 (en) 2014-09-17
EP3208617A2 (en) 2017-08-23
WO2013068373A2 (en) 2013-05-16
US9863965B2 (en) 2018-01-09
EP3208617B1 (en) 2021-02-24
US20140295467A1 (en) 2014-10-02
CN103917876B (zh) 2018-02-02

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JP6388284B2 (ja) スタチン治療を受けている冠動脈疾患患者の心血管転帰を予測するためのリピドミックバイオマーカー
JP6388283B2 (ja) スタチン治療を受けていない冠動脈疾患患者の心血管転帰を予測するためのリピドミックバイオマーカー
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