JP6382232B2 - 脳全体の傍血管経路を老廃物のクリアランス機能について評価するための方法、およびそれに基づいて神経変性障害を治療するための方法 - Google Patents
脳全体の傍血管経路を老廃物のクリアランス機能について評価するための方法、およびそれに基づいて神経変性障害を治療するための方法 Download PDFInfo
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361767546P | 2013-02-21 | 2013-02-21 | |
| US61/767,546 | 2013-02-21 | ||
| US201361862321P | 2013-08-05 | 2013-08-05 | |
| US61/862,321 | 2013-08-05 | ||
| US201461942447P | 2014-02-20 | 2014-02-20 | |
| US61/942,447 | 2014-02-20 | ||
| PCT/US2014/017606 WO2014130777A1 (en) | 2013-02-21 | 2014-02-21 | Methods for evaluating brain-wide paravascular pathway for waste clearance function and methods for treating neurodegenerative disorders based thereon |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016509061A JP2016509061A (ja) | 2016-03-24 |
| JP2016509061A5 JP2016509061A5 (enExample) | 2017-06-15 |
| JP6382232B2 true JP6382232B2 (ja) | 2018-08-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015558986A Active JP6382232B2 (ja) | 2013-02-21 | 2014-02-21 | 脳全体の傍血管経路を老廃物のクリアランス機能について評価するための方法、およびそれに基づいて神経変性障害を治療するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9901650B2 (enExample) |
| EP (1) | EP2964270A4 (enExample) |
| JP (1) | JP6382232B2 (enExample) |
| CN (1) | CN105228652A (enExample) |
| WO (1) | WO2014130777A1 (enExample) |
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| US10874798B2 (en) | 2014-10-15 | 2020-12-29 | P&X Medical Nv | Therapeutic applications of artificial cerebrospinal fluid and tools provided therefor |
| US9681821B2 (en) | 2015-02-19 | 2017-06-20 | Synaptive Medical (Barbados) Inc. | Methods for measuring global glymphatic flow using magnetic resonance imaging |
| EP3325992B1 (en) | 2015-07-24 | 2026-01-28 | Northeastern University | Quantitative magnetic resonance imaging of the vasculature |
| WO2017223092A1 (en) * | 2016-06-21 | 2017-12-28 | New York University | System and method for in vivo detection of cerebrospinal fluid egress |
| US20190282792A1 (en) * | 2016-07-20 | 2019-09-19 | P&X Medical Nv | Compounds for use in methods for treating glaucoma and retinal diseases |
| USD867397S1 (en) * | 2016-07-22 | 2019-11-19 | Koninklijke Philips N.V. | Display screen with icon |
| US10342221B2 (en) * | 2016-08-19 | 2019-07-09 | University Of Southern California | Generation of an inducible pericyte-specific CRE mouse model |
| US11426577B2 (en) * | 2016-08-26 | 2022-08-30 | Wisconsin Alumni Research Foundation | Neuromodulation to modulate glymphatic clearance |
| SG10202107367SA (en) | 2016-12-31 | 2021-08-30 | Bioxcel Therapeutics Inc | Use of sublingual dexmedetomidine for the treatment of agitation |
| CN106887025B (zh) | 2017-01-16 | 2019-06-11 | 浙江大学 | 一种基于栈式自编码器的混合示踪剂动态pet浓度分布图像重建的方法 |
| CN106801055A (zh) * | 2017-01-23 | 2017-06-06 | 徐辉 | 一种检测aqp‑4自身抗体的芯片、制备方法及其应用 |
| WO2018174721A2 (en) | 2017-03-23 | 2018-09-27 | Brainwidesolutions As | Indicator fluids, systems, and methods for assessing movement of substances within, to or from a cerebrospinal fluid, brain or spinal cord compartment of a cranio-spinal cavity of a human |
| CN108129563B (zh) * | 2018-01-12 | 2020-12-01 | 沈阳眼产业技术研究院有限公司 | 一种抗aqp4的小分子抗体及其应用 |
| KR102080023B1 (ko) * | 2018-01-29 | 2020-02-21 | 주식회사 종근당 | 에스오메프라졸 및 탄산수소나트륨을 포함하는 안정한 약제학적 조성물 |
| KR102006777B1 (ko) | 2018-01-29 | 2019-10-08 | 주식회사 종근당 | 에스오메프라졸 및 탄산수소나트륨을 포함하는 약제학적 제제 |
| WO2019157119A1 (en) * | 2018-02-07 | 2019-08-15 | University Of Cincinnati | System and method for detecting small blood-tissue barrier disruption |
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| WO2019200342A1 (en) * | 2018-04-12 | 2019-10-17 | The J. David Gladstone Institutes | Methods for treating apoe4/4-associated disorders |
| JP6945493B2 (ja) * | 2018-05-09 | 2021-10-06 | 富士フイルム株式会社 | 医用画像処理装置、方法およびプログラム |
| ES3004544T3 (en) | 2018-06-27 | 2025-03-12 | Bioxcel Therapeutics Inc | Film formulations containing dexmedetomidine and methods of producing them |
| WO2020014394A1 (en) * | 2018-07-10 | 2020-01-16 | The Board Of Trustees Of The Leland Stanford Junior University | Intranasal vasopressin treatment of social deficits in autism |
| US20210298662A1 (en) * | 2018-07-27 | 2021-09-30 | Northeastern University | Diagnosis of Dementia by Vascular Magnetic Resonance Imaging |
| WO2020040438A1 (ko) | 2018-08-23 | 2020-02-27 | 주식회사 종근당 | 에스오메프라졸 및 탄산수소나트륨을 포함하는 우수한 방출특성을 갖는 약제학적 제제 |
| US20220280423A1 (en) * | 2018-10-04 | 2022-09-08 | University Of Rochester | Glymphatic delivery by manipulating plasma osmolarity |
| WO2020072357A1 (en) | 2018-10-04 | 2020-04-09 | University Of Rochester | Improvement of glymphatic delivery by manipulating plasma osmolarity |
| WO2020142696A1 (en) | 2019-01-03 | 2020-07-09 | Northeastern University | Quantitative measurement of disruptions in the blood brain barrier |
| KR102307479B1 (ko) * | 2019-02-12 | 2021-09-30 | 단국대학교 천안캠퍼스 산학협력단 | 신경전달물질 기반의 뇌 지도 작성 방법 및 뇌 지도를 이용하는 용도 |
| WO2020166979A2 (ko) * | 2019-02-12 | 2020-08-20 | 주식회사 뉴로비스 | 신경전달물질 기반의 뇌 지도 작성 방법 및 뇌 지도를 이용하는 용도 |
| WO2020185758A1 (en) | 2019-03-12 | 2020-09-17 | Bayer Healthcare Llc | Systems and methods for assessing a likelihood of cteph and identifying characteristics indicative thereof |
| US12144583B2 (en) | 2019-03-21 | 2024-11-19 | Synaptec Network, Inc. | Diffusion tensor MR to monitor glymphatic system |
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| US20240024288A1 (en) | 2019-07-19 | 2024-01-25 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
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| WO2021052850A1 (de) | 2019-09-18 | 2021-03-25 | Bayer Aktiengesellschaft | Erzeugung von mrt-aufnahmen der leber |
| JP7542060B2 (ja) | 2019-09-18 | 2024-08-29 | バイエル、アクチエンゲゼルシャフト | 教師あり学習によって訓練された予測モデルによるmri画像の予測 |
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| US11908131B2 (en) * | 2020-02-14 | 2024-02-20 | University Of Southern California | Mapping brain perivascular spaces |
| EP4128261A1 (de) | 2020-04-03 | 2023-02-08 | Bayer Aktiengesellschaft | Erzeugen von radiologischen aufnahmen |
| US11559626B2 (en) | 2020-04-08 | 2023-01-24 | Medtronic, Inc. | Means to treat Alzheimer's disease via flushing of brain parenchyma |
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| CN113781547B (zh) * | 2021-08-05 | 2024-05-31 | 东软医疗系统股份有限公司 | 头部对称轴识别方法及装置、存储介质、计算机设备 |
| US20240350106A1 (en) * | 2021-08-17 | 2024-10-24 | University Of Virginia Patent Foundation | Systems, methods, and computer readable media for parametric fdg pet quantification, segmentation and classification of abnormalities |
| EP4401622A4 (en) * | 2021-09-14 | 2025-07-09 | Applied Cognition Inc | NON-INVASIVE ASSESSMENT OF GLYMPHATIC FLOW AND NEURODEGENERATION FROM A WEARABLE DEVICE |
| US20250235554A1 (en) * | 2021-10-25 | 2025-07-24 | Novartis Ag | Methods for improving adeno-associated virus (aav) delivery |
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| US12004874B2 (en) * | 2022-10-24 | 2024-06-11 | Applied Cognition, Inc. | Wearable device and method for non-invasive assessment of glymphatic flow |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| AU2024220563A1 (en) | 2023-02-16 | 2025-08-14 | University Of Rochester | Improving glymphatic-lymphatic efflux |
| CN121729176A (zh) * | 2023-04-07 | 2026-03-24 | 哈佛学院院长及董事 | 磁共振成像校准系统和方法 |
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