JP6370217B2 - ヒドロキシエチル澱粉誘導体の製造方法 - Google Patents

ヒドロキシエチル澱粉誘導体の製造方法 Download PDF

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Publication number
JP6370217B2
JP6370217B2 JP2014516345A JP2014516345A JP6370217B2 JP 6370217 B2 JP6370217 B2 JP 6370217B2 JP 2014516345 A JP2014516345 A JP 2014516345A JP 2014516345 A JP2014516345 A JP 2014516345A JP 6370217 B2 JP6370217 B2 JP 6370217B2
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solution
hydroxyethyl starch
iron
temperature
complex
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Japanese (ja)
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JP2014520188A5 (enExample
JP2014520188A (ja
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ツィンマーマン・ヴェルナー
ルコフチック・ヤン
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Serumwerk Bernburg Ag
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Serumwerk Bernburg Ag
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/08—Ethers
    • C08B31/12—Ethers having alkyl or cycloalkyl radicals substituted by heteroatoms, e.g. hydroxyalkyl or carboxyalkyl starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/08—Ethers
    • C08B31/10—Alkyl or cycloalkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2014516345A 2011-06-21 2012-06-21 ヒドロキシエチル澱粉誘導体の製造方法 Active JP6370217B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11170761.8 2011-06-21
EP11170761A EP2537866A1 (en) 2011-06-21 2011-06-21 Hydroxyethyl starch derivatives, method for manufacturing the same and therapeutical uses thereof
PCT/EP2012/061958 WO2012175608A1 (en) 2011-06-21 2012-06-21 Method for manufacturing hydroxyethyl starch derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018059264A Division JP2018100424A (ja) 2011-06-21 2018-03-27 ヒドロキシエチル澱粉誘導体の製造方法

Publications (3)

Publication Number Publication Date
JP2014520188A JP2014520188A (ja) 2014-08-21
JP2014520188A5 JP2014520188A5 (enExample) 2015-07-23
JP6370217B2 true JP6370217B2 (ja) 2018-08-08

Family

ID=44799422

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014516345A Active JP6370217B2 (ja) 2011-06-21 2012-06-21 ヒドロキシエチル澱粉誘導体の製造方法
JP2018059264A Pending JP2018100424A (ja) 2011-06-21 2018-03-27 ヒドロキシエチル澱粉誘導体の製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018059264A Pending JP2018100424A (ja) 2011-06-21 2018-03-27 ヒドロキシエチル澱粉誘導体の製造方法

Country Status (22)

Country Link
US (2) US9181353B2 (enExample)
EP (2) EP2537866A1 (enExample)
JP (2) JP6370217B2 (enExample)
CN (2) CN103649128B (enExample)
BR (1) BR112013032901A2 (enExample)
CA (1) CA2837784C (enExample)
CY (1) CY1121976T1 (enExample)
DK (1) DK2723774T3 (enExample)
ES (1) ES2733767T3 (enExample)
HK (1) HK1220218A1 (enExample)
HR (1) HRP20191173T1 (enExample)
HU (1) HUE044428T2 (enExample)
LT (1) LT2723774T (enExample)
MX (1) MX337682B (enExample)
PL (1) PL2723774T3 (enExample)
PT (1) PT2723774T (enExample)
RS (1) RS59021B1 (enExample)
SI (1) SI2723774T1 (enExample)
SM (1) SMT201900430T1 (enExample)
TR (1) TR201909574T4 (enExample)
TW (1) TWI564010B (enExample)
WO (1) WO2012175608A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6616725B2 (ja) * 2016-03-31 2019-12-04 日本製紙株式会社 塗工紙用澱粉
AU2020206021B2 (en) 2019-01-10 2025-05-08 Pharmacosmos Holding A/S Treating iron deficiency in subjects at risk of cardiovascular adverse events and iron for the management of atrial fibrillation
CN114286682A (zh) 2019-02-09 2022-04-05 法码科思莫斯控股有限公司 治疗具有心血管不良事件风险的个体的铁缺乏以及用于治疗心房颤动的铁
JP2024529536A (ja) 2021-08-03 2024-08-06 ファーマコスモス ホールディング エー／エス コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物
CN117547549A (zh) * 2023-11-09 2024-02-13 黑龙江八一农垦大学 适用于犬arf的腹膜透析液与助清除剂的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639588A (en) * 1966-10-22 1972-02-01 Fisons Pharmaceuticals Ltd Pharmaceutical compositions containing ferric hydroxide complexed with dextran or dextrin heptonic acids
US4370476A (en) * 1979-07-17 1983-01-25 Usher Thomas C Dextran polycarboxylic acids, ferric hydroxide complexes
GB8902894D0 (en) * 1989-02-09 1989-03-30 Fisons Plc Compositions
JPH0566372A (ja) * 1991-09-10 1993-03-19 Fukui Megane Kogyo Kk 金属製眼鏡フレーム部品の製造方法
JPH0776524A (ja) * 1993-07-13 1995-03-20 Takeda Chem Ind Ltd 動物用抗貧血剤
DK172860B1 (da) * 1998-03-25 1999-08-16 Pharmacosmos Holding As Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
DK173138B1 (da) 1998-11-20 2000-02-07 Pharmacosmos Holding As Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma
EP1762250A1 (en) * 2005-09-12 2007-03-14 Fresenius Kabi Deutschland GmbH Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
WO2009024518A1 (en) * 2007-08-17 2009-02-26 Akzo Nobel N.V. Alkali metal salt of glutamic acid n,n-diacetic acid, a process to prepare such salt, and the use thereof
TWI469965B (zh) * 2008-12-22 2015-01-21 Ono Pharmaceutical Co 乙炔基吲哚化合物
JP5397991B2 (ja) * 2009-04-01 2014-01-22 学校法人東京農業大学 乳酸菌を用いたビタミンｂ１２の定量方法

Also Published As

Publication number Publication date
US9631032B2 (en) 2017-04-25
RS59021B1 (sr) 2019-08-30
SI2723774T1 (sl) 2019-08-30
HK1220218A1 (zh) 2017-04-28
HUE044428T2 (hu) 2019-10-28
CA2837784C (en) 2019-10-15
JP2018100424A (ja) 2018-06-28
TWI564010B (zh) 2017-01-01
MX2013015075A (es) 2014-04-14
SMT201900430T1 (it) 2019-09-09
CN103649128A (zh) 2014-03-19
CY1121976T1 (el) 2020-10-14
WO2012175608A1 (en) 2012-12-27
CA2837784A1 (en) 2012-12-27
CN105348401A (zh) 2016-02-24
US20140128594A1 (en) 2014-05-08
BR112013032901A2 (pt) 2017-01-24
LT2723774T (lt) 2019-08-12
US20160046733A1 (en) 2016-02-18
CN103649128B (zh) 2016-02-10
MX337682B (es) 2016-03-15
EP2723774A1 (en) 2014-04-30
PT2723774T (pt) 2019-07-15
HRP20191173T1 (hr) 2019-10-04
PL2723774T3 (pl) 2019-10-31
US9181353B2 (en) 2015-11-10
ES2733767T3 (es) 2019-12-02
TR201909574T4 (en) 2019-08-21
EP2537866A1 (en) 2012-12-26
JP2014520188A (ja) 2014-08-21
DK2723774T3 (da) 2019-07-15
EP2723774B1 (en) 2019-04-03
TW201315474A (zh) 2013-04-16

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