JP2014520188A5 - - Google Patents
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- Publication number
- JP2014520188A5 JP2014520188A5 JP2014516345A JP2014516345A JP2014520188A5 JP 2014520188 A5 JP2014520188 A5 JP 2014520188A5 JP 2014516345 A JP2014516345 A JP 2014516345A JP 2014516345 A JP2014516345 A JP 2014516345A JP 2014520188 A5 JP2014520188 A5 JP 2014520188A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- hydroxyethyl starch
- temperature
- producing
- value
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001612 Hydroxyethyl starch Polymers 0.000 claims description 47
- 229940050526 hydroxyethylstarch Drugs 0.000 claims description 44
- 238000004519 manufacturing process Methods 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 20
- 238000010438 heat treatment Methods 0.000 claims description 11
- 150000002506 iron compounds Chemical class 0.000 claims description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- -1 hydroxylethyl Chemical group 0.000 claims description 5
- 150000002505 iron Chemical class 0.000 claims description 4
- 229920002472 Starch Polymers 0.000 claims description 3
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- KWMLJOLKUYYJFJ-UHFFFAOYSA-N 2,3,4,5,6,7-Hexahydroxyheptanoic acid Chemical group OCC(O)C(O)C(O)C(O)C(O)C(O)=O KWMLJOLKUYYJFJ-UHFFFAOYSA-N 0.000 claims description 2
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical group [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 229920001592 potato starch Polymers 0.000 claims description 2
- 230000000087 stabilizing effect Effects 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 238000006467 substitution reaction Methods 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11170761.8 | 2011-06-21 | ||
| EP11170761A EP2537866A1 (en) | 2011-06-21 | 2011-06-21 | Hydroxyethyl starch derivatives, method for manufacturing the same and therapeutical uses thereof |
| PCT/EP2012/061958 WO2012175608A1 (en) | 2011-06-21 | 2012-06-21 | Method for manufacturing hydroxyethyl starch derivatives |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018059264A Division JP2018100424A (ja) | 2011-06-21 | 2018-03-27 | ヒドロキシエチル澱粉誘導体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520188A JP2014520188A (ja) | 2014-08-21 |
| JP2014520188A5 true JP2014520188A5 (enExample) | 2015-07-23 |
| JP6370217B2 JP6370217B2 (ja) | 2018-08-08 |
Family
ID=44799422
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014516345A Active JP6370217B2 (ja) | 2011-06-21 | 2012-06-21 | ヒドロキシエチル澱粉誘導体の製造方法 |
| JP2018059264A Pending JP2018100424A (ja) | 2011-06-21 | 2018-03-27 | ヒドロキシエチル澱粉誘導体の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018059264A Pending JP2018100424A (ja) | 2011-06-21 | 2018-03-27 | ヒドロキシエチル澱粉誘導体の製造方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9181353B2 (enExample) |
| EP (2) | EP2537866A1 (enExample) |
| JP (2) | JP6370217B2 (enExample) |
| CN (2) | CN103649128B (enExample) |
| BR (1) | BR112013032901A2 (enExample) |
| CA (1) | CA2837784C (enExample) |
| CY (1) | CY1121976T1 (enExample) |
| DK (1) | DK2723774T3 (enExample) |
| ES (1) | ES2733767T3 (enExample) |
| HK (1) | HK1220218A1 (enExample) |
| HR (1) | HRP20191173T1 (enExample) |
| HU (1) | HUE044428T2 (enExample) |
| LT (1) | LT2723774T (enExample) |
| MX (1) | MX337682B (enExample) |
| PL (1) | PL2723774T3 (enExample) |
| PT (1) | PT2723774T (enExample) |
| RS (1) | RS59021B1 (enExample) |
| SI (1) | SI2723774T1 (enExample) |
| SM (1) | SMT201900430T1 (enExample) |
| TR (1) | TR201909574T4 (enExample) |
| TW (1) | TWI564010B (enExample) |
| WO (1) | WO2012175608A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6616725B2 (ja) * | 2016-03-31 | 2019-12-04 | 日本製紙株式会社 | 塗工紙用澱粉 |
| AU2020206021B2 (en) | 2019-01-10 | 2025-05-08 | Pharmacosmos Holding A/S | Treating iron deficiency in subjects at risk of cardiovascular adverse events and iron for the management of atrial fibrillation |
| CN114286682A (zh) | 2019-02-09 | 2022-04-05 | 法码科思莫斯控股有限公司 | 治疗具有心血管不良事件风险的个体的铁缺乏以及用于治疗心房颤动的铁 |
| JP2024529536A (ja) | 2021-08-03 | 2024-08-06 | ファーマコスモス ホールディング エー／エス | コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物 |
| CN117547549A (zh) * | 2023-11-09 | 2024-02-13 | 黑龙江八一农垦大学 | 适用于犬arf的腹膜透析液与助清除剂的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3639588A (en) * | 1966-10-22 | 1972-02-01 | Fisons Pharmaceuticals Ltd | Pharmaceutical compositions containing ferric hydroxide complexed with dextran or dextrin heptonic acids |
| US4370476A (en) * | 1979-07-17 | 1983-01-25 | Usher Thomas C | Dextran polycarboxylic acids, ferric hydroxide complexes |
| GB8902894D0 (en) * | 1989-02-09 | 1989-03-30 | Fisons Plc | Compositions |
| JPH0566372A (ja) * | 1991-09-10 | 1993-03-19 | Fukui Megane Kogyo Kk | 金属製眼鏡フレーム部品の製造方法 |
| JPH0776524A (ja) * | 1993-07-13 | 1995-03-20 | Takeda Chem Ind Ltd | 動物用抗貧血剤 |
| DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
| EP1762250A1 (en) * | 2005-09-12 | 2007-03-14 | Fresenius Kabi Deutschland GmbH | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine |
| WO2009024518A1 (en) * | 2007-08-17 | 2009-02-26 | Akzo Nobel N.V. | Alkali metal salt of glutamic acid n,n-diacetic acid, a process to prepare such salt, and the use thereof |
| TWI469965B (zh) * | 2008-12-22 | 2015-01-21 | Ono Pharmaceutical Co | 乙炔基吲哚化合物 |
| JP5397991B2 (ja) * | 2009-04-01 | 2014-01-22 | 学校法人東京農業大学 | 乳酸菌を用いたビタミンｂ１２の定量方法 |
-
2011
- 2011-06-21 EP EP11170761A patent/EP2537866A1/en not_active Withdrawn
-
2012
- 2012-06-21 TR TR2019/09574T patent/TR201909574T4/en unknown
- 2012-06-21 BR BR112013032901A patent/BR112013032901A2/pt not_active Application Discontinuation
- 2012-06-21 PL PL12737229T patent/PL2723774T3/pl unknown
- 2012-06-21 WO PCT/EP2012/061958 patent/WO2012175608A1/en not_active Ceased
- 2012-06-21 TW TW101122208A patent/TWI564010B/zh active
- 2012-06-21 SM SM20190430T patent/SMT201900430T1/it unknown
- 2012-06-21 CA CA2837784A patent/CA2837784C/en active Active
- 2012-06-21 CN CN201280029882.3A patent/CN103649128B/zh active Active
- 2012-06-21 PT PT12737229T patent/PT2723774T/pt unknown
- 2012-06-21 MX MX2013015075A patent/MX337682B/es active IP Right Grant
- 2012-06-21 RS RS20190850A patent/RS59021B1/sr unknown
- 2012-06-21 HR HRP20191173TT patent/HRP20191173T1/hr unknown
- 2012-06-21 DK DK12737229.0T patent/DK2723774T3/da active
- 2012-06-21 SI SI201231627T patent/SI2723774T1/sl unknown
- 2012-06-21 EP EP12737229.0A patent/EP2723774B1/en active Active
- 2012-06-21 CN CN201510909616.5A patent/CN105348401A/zh active Pending
- 2012-06-21 HU HUE12737229 patent/HUE044428T2/hu unknown
- 2012-06-21 US US14/127,766 patent/US9181353B2/en active Active
- 2012-06-21 JP JP2014516345A patent/JP6370217B2/ja active Active
- 2012-06-21 ES ES12737229T patent/ES2733767T3/es active Active
- 2012-06-21 LT LTEP12737229.0T patent/LT2723774T/lt unknown
-
2015
- 2015-10-26 US US14/922,897 patent/US9631032B2/en active Active
-
2016
- 2016-07-12 HK HK16108112.8A patent/HK1220218A1/zh unknown
-
2018
- 2018-03-27 JP JP2018059264A patent/JP2018100424A/ja active Pending
-
2019
- 2019-07-03 CY CY20191100704T patent/CY1121976T1/el unknown
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