JP6367717B2 - 誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入 - Google Patents

誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入 Download PDF

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Publication number
JP6367717B2
JP6367717B2 JP2014556753A JP2014556753A JP6367717B2 JP 6367717 B2 JP6367717 B2 JP 6367717B2 JP 2014556753 A JP2014556753 A JP 2014556753A JP 2014556753 A JP2014556753 A JP 2014556753A JP 6367717 B2 JP6367717 B2 JP 6367717B2
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fluid
droplet
volume
droplets
channel
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JP2015508705A5 (enExample
JP2015508705A (ja
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ペイ−ユ・チョウ
ティン−シアン・エス・ウー
スン−ヨン・パク
マイケル・エー・テイテル
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University of California
University of California Berkeley
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    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D11/00—Control of flow ratio
    • G05D11/02—Controlling ratio of two or more flows of fluid or fluent material
    • G05D11/13—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/24—Probes
    • G01N29/2418—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
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    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
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    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
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    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2400/0442—Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10T137/00—Fluid handling
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  • Dispersion Chemistry (AREA)
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  • Clinical Laboratory Science (AREA)
  • General Physics & Mathematics (AREA)
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  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Fluid Mechanics (AREA)
  • Electromagnetism (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micromachines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2014556753A 2012-02-09 2013-02-08 誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入 Expired - Fee Related JP6367717B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/370,196 2012-02-09
US13/370,196 US9176504B2 (en) 2011-02-11 2012-02-09 High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation
PCT/US2013/025434 WO2013120016A2 (en) 2012-02-09 2013-02-08 High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation

Related Child Applications (1)

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JP2017172951A Division JP2018034154A (ja) 2012-02-09 2017-09-08 誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入

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JP2015508705A JP2015508705A (ja) 2015-03-23
JP2015508705A5 JP2015508705A5 (enExample) 2016-03-31
JP6367717B2 true JP6367717B2 (ja) 2018-08-01

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JP2014556753A Expired - Fee Related JP6367717B2 (ja) 2012-02-09 2013-02-08 誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入
JP2017172951A Pending JP2018034154A (ja) 2012-02-09 2017-09-08 誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入

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JP2017172951A Pending JP2018034154A (ja) 2012-02-09 2017-09-08 誘発されたキャビテーションによって駆動される高速オンデマンド型液滴生成および単一細胞封入

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US (2) US9176504B2 (enExample)
EP (2) EP3410124B1 (enExample)
JP (2) JP6367717B2 (enExample)
KR (1) KR20150016929A (enExample)
CN (2) CN104321652B (enExample)
AU (2) AU2013216804B2 (enExample)
CA (1) CA2864138C (enExample)
ES (2) ES2687684T3 (enExample)
WO (1) WO2013120016A2 (enExample)

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