JP6364472B2 - 抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体 - Google Patents

抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体 Download PDF

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JP6364472B2
JP6364472B2 JP2016503187A JP2016503187A JP6364472B2 JP 6364472 B2 JP6364472 B2 JP 6364472B2 JP 2016503187 A JP2016503187 A JP 2016503187A JP 2016503187 A JP2016503187 A JP 2016503187A JP 6364472 B2 JP6364472 B2 JP 6364472B2
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pyridin
methyl
oxy
carbamoyl
pyrazol
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JP2016516724A (ja
JP2016516724A5 (enExample
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ディー． カウフマン，マイケル
ディー． カウフマン，マイケル
マルコム コールドウェル，ティモシー
マルコム コールドウェル，ティモシー
エル． フリン，ダニエル
エル． フリン，ダニエル
シー． パット，ウィリアム
シー． パット，ウィリアム
サマラクーン，ティワンカ
ヴォゲティ，ラクシュミナラヤナ
エム． イェイツ，カレン
エム． イェイツ，カレン
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デシフェラ ファーマシューティカルズ，エルエルシー
デシフェラ ファーマシューティカルズ，エルエルシー
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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JP2016503187A 2013-03-15 2014-03-14 抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体 Active JP6364472B2 (ja)

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US201361789971P 2013-03-15 2013-03-15
US61/789,971 2013-03-15
PCT/US2014/029664 WO2014145028A2 (en) 2013-03-15 2014-03-14 N-acyl-n'-(pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activities

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JP2018126337A Pending JP2018184416A (ja) 2013-03-15 2018-07-02 抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体
JP2020068792A Active JP6985448B2 (ja) 2013-03-15 2020-04-07 抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体

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JP2020068792A Active JP6985448B2 (ja) 2013-03-15 2020-04-07 抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018184416A (ja) * 2013-03-15 2018-11-22 デシフェラ ファーマシューティカルズ，エルエルシー 抗がんおよび抗増殖活性を示すｎ−アシル−ｎ’−（ピリジン−２−イル）尿素および類似体
US11679110B2 (en) 2018-12-28 2023-06-20 Deciphera Pharmaceuticals, Llc Methods of treating disorders using CSF1R inhibitors
US12447149B2 (en) 2023-12-08 2025-10-21 Deciphera Pharmaceuticals, Llc Formulations of vimseltinib
US12509443B2 (en) 2024-05-01 2025-12-30 Deciphera Pharmaceuticals, Llc CSF-1R inhibitors and methods of use thereof
US12528787B2 (en) 2023-12-08 2026-01-20 Deciphera Pharmaceuticals, Llc Solid state forms of a kinase inhibitor
US12617775B2 (en) 2024-05-01 2026-05-05 Deciphera Pharmaceuticals, Llc Processes of making CSF-1R inhibitors and methods of use thereof

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Publication number Priority date Publication date Assignee Title
JP5335056B2 (ja) 2011-11-16 2013-11-06 住友電気工業株式会社 ボルト用アルミニウム合金線及びボルト並びにそれらの製造方法
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