JP6363595B2 - 歯周炎および歯周炎に関連する疾患を処置または予防する方法 - Google Patents

歯周炎および歯周炎に関連する疾患を処置または予防する方法 Download PDF

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JP6363595B2
JP6363595B2 JP2015518554A JP2015518554A JP6363595B2 JP 6363595 B2 JP6363595 B2 JP 6363595B2 JP 2015518554 A JP2015518554 A JP 2015518554A JP 2015518554 A JP2015518554 A JP 2015518554A JP 6363595 B2 JP6363595 B2 JP 6363595B2
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periodontitis
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porphyromonas gingivalis
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ジョージ・ハジシェンガリス
ジョン・ディ・ランブリス
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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    • G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
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JP2015518554A 2012-06-20 2013-06-19 歯周炎および歯周炎に関連する疾患を処置または予防する方法 Active JP6363595B2 (ja)

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US201261662022P 2012-06-20 2012-06-20
US61/662,022 2012-06-20
US13/801,096 2013-03-13
US13/801,096 US9579360B2 (en) 2012-06-20 2013-03-13 Methods of treating or preventing periodontitis and diseases associated with periodontitis
PCT/US2013/046599 WO2013192319A1 (en) 2012-06-20 2013-06-19 Methods of treating or preventing periodontitis and diseases associated with periodontitis

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JP6363595B2 true JP6363595B2 (ja) 2018-07-25

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CN (1) CN104640567A (enrdf_load_html_response)
AU (1) AU2013277217B2 (enrdf_load_html_response)
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HUE047375T2 (hu) 2011-09-07 2020-04-28 Univ Pennsylvania Javított farmakokinetikai tulajdonságokkal rendelkezõ compstatin analógok
US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
AU2015223075A1 (en) 2014-02-25 2016-09-01 Achillion Pharmaceuticals, Inc. Phosphonate compounds for treatment of complement mediated disorders
NZ727420A (en) 2014-06-12 2018-06-29 Ra Pharmaceuticals Inc Modulation of complement activity
WO2016123371A1 (en) 2015-01-28 2016-08-04 Ra Pharmaceuticals, Inc. Modulators of complement activity
WO2017035401A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amide compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
WO2017035409A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
WO2017035405A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amino compounds for treatment of immune and inflammatory disorders
KR20180094913A (ko) 2015-12-16 2018-08-24 라 파마슈티컬스 인코포레이티드 보체 활성의 조절인자
CN110087668A (zh) 2016-12-07 2019-08-02 Ra制药公司 补体活性的调节剂
WO2018160891A1 (en) 2017-03-01 2018-09-07 Achillion Pharmaceutical, Inc. Pharmaceutical compounds for treatment of medical disorders
WO2018160889A1 (en) 2017-03-01 2018-09-07 Achillion Pharmaceuticals, Inc. Aryl, heteroary, and heterocyclic pharmaceutical compounds for treatment of medical disorders
EP3661493A4 (en) 2017-08-02 2021-04-14 Achillion Pharmaceuticals, Inc. TREATMENT DIET FOR THE TREATMENT OF PAROXYSTIC NOCTURAL HEMOGLOBINURIA
US20210000927A1 (en) 2017-12-04 2021-01-07 Ra Pharmaceuticals, Inc. Modulators of complement activity
WO2019118938A1 (en) * 2017-12-15 2019-06-20 Apellis Pharmaceuticals, Inc. Dosing regimens and related compositions and methods
HUE057693T2 (hu) 2018-04-06 2022-05-28 Univ Pennsylvania Fokozott oldhatóságú és javított farmakokinetikai tulajdonságú kompsztatin analógok
MX2021002640A (es) 2018-09-06 2021-07-16 Achillion Pharmaceuticals Inc Formas morficas de los inhibidores del factor d del complemento.
JP7443375B2 (ja) 2018-09-06 2024-03-05 アキリオン ファーマシューティカルズ， インコーポレーテッド 医学的障害の治療のための大環状化合物
CN112996497A (zh) 2018-09-25 2021-06-18 艾其林医药公司 补体因子d抑制剂的形态形式
MX2021007329A (es) 2018-12-17 2021-09-21 Achillion Pharmaceuticals Inc Dosificacion dirigida para el tratamiento de trastornos mediados por el complemento.
CA3131927A1 (en) 2019-03-08 2020-09-17 Ra Pharmaceuticals, Inc. Modulators of complement activity
JP2022527508A (ja) 2019-03-29 2022-06-02 ラ ファーマシューティカルズ インコーポレイテッド 補体モジュレータ及び関連方法
BR112021017820A2 (pt) 2019-04-24 2022-02-08 Ra Pharmaceuticals Inc Composições e métodos para modulação da atividade de complemento

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HUE047375T2 (hu) * 2011-09-07 2020-04-28 Univ Pennsylvania Javított farmakokinetikai tulajdonságokkal rendelkezõ compstatin analógok
US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis

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JP2015523999A (ja) 2015-08-20
EP2863949A4 (en) 2016-03-02
US20130344082A1 (en) 2013-12-26
IN2015DN00438A (enrdf_load_html_response) 2015-06-19
WO2013192319A1 (en) 2013-12-27
CA2877299A1 (en) 2013-12-27
US10668135B2 (en) 2020-06-02
AU2013277217A2 (en) 2015-01-22
EP2863949B1 (en) 2019-01-23
US20170202935A1 (en) 2017-07-20
CN104640567A (zh) 2015-05-20
CA2877299C (en) 2022-07-12
US9579360B2 (en) 2017-02-28
AU2013277217B2 (en) 2018-03-08
AU2013277217A1 (en) 2015-01-22
EP2863949A1 (en) 2015-04-29

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