JP6335875B2 - 癌の治療のための診断法及び組成物 - Google Patents
癌の治療のための診断法及び組成物 Download PDFInfo
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- JP6335875B2 JP6335875B2 JP2015503315A JP2015503315A JP6335875B2 JP 6335875 B2 JP6335875 B2 JP 6335875B2 JP 2015503315 A JP2015503315 A JP 2015503315A JP 2015503315 A JP2015503315 A JP 2015503315A JP 6335875 B2 JP6335875 B2 JP 6335875B2
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- vegf antagonist
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- cox2
- vegf
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/686—Polymerase chain reaction [PCR]
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/755—Factors VIII, e.g. factor VIII C [AHF], factor VIII Ag [VWF]
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- G01N2333/90248—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one of the donors, and incorporation of one atom of oxygen 1.14.13
- G01N2333/90251—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one of the donors, and incorporation of one atom of oxygen 1.14.13 with a definite EC number (1.14.13.-)
- G01N2333/90254—Nitric-oxide synthase (NOS; 1.14.13.39)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Biochemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
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- Cell Biology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261618199P | 2012-03-30 | 2012-03-30 | |
| US61/618,199 | 2012-03-30 | ||
| PCT/US2013/031760 WO2013148288A1 (en) | 2012-03-30 | 2013-03-14 | Diagnostic methods and compositions for treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017229130A Division JP2018075015A (ja) | 2012-03-30 | 2017-11-29 | 癌の治療のための診断法及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516806A JP2015516806A (ja) | 2015-06-18 |
| JP2015516806A5 JP2015516806A5 (https=) | 2016-05-12 |
| JP6335875B2 true JP6335875B2 (ja) | 2018-05-30 |
Family
ID=49261061
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015503315A Expired - Fee Related JP6335875B2 (ja) | 2012-03-30 | 2013-03-14 | 癌の治療のための診断法及び組成物 |
| JP2017229130A Pending JP2018075015A (ja) | 2012-03-30 | 2017-11-29 | 癌の治療のための診断法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017229130A Pending JP2018075015A (ja) | 2012-03-30 | 2017-11-29 | 癌の治療のための診断法及び組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20150056190A1 (https=) |
| EP (1) | EP2830661A4 (https=) |
| JP (2) | JP6335875B2 (https=) |
| KR (1) | KR20140142719A (https=) |
| CN (1) | CN104271157A (https=) |
| AU (2) | AU2013240234B2 (https=) |
| BR (1) | BR112014024219A8 (https=) |
| CA (1) | CA2867588A1 (https=) |
| HK (1) | HK1200739A1 (https=) |
| IL (1) | IL234678A0 (https=) |
| MX (1) | MX2014011582A (https=) |
| RU (1) | RU2666627C2 (https=) |
| SG (2) | SG11201406184XA (https=) |
| WO (1) | WO2013148288A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10456470B2 (en) | 2013-08-30 | 2019-10-29 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| US10617755B2 (en) | 2013-08-30 | 2020-04-14 | Genentech, Inc. | Combination therapy for the treatment of glioblastoma |
| JP2015096049A (ja) * | 2013-11-15 | 2015-05-21 | 凸版印刷株式会社 | Vegf阻害剤長期奏功性予測方法 |
| WO2015082880A1 (en) * | 2013-12-02 | 2015-06-11 | Astrazeneca Ab | Methods of selecting treatment regimens |
| WO2016011052A1 (en) * | 2014-07-14 | 2016-01-21 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| ES2856348T3 (es) | 2014-09-17 | 2021-09-27 | Merck Patent Gmbh | Un método para el tratamiento de cánceres sólidos y/o metástasis de los mismos, medicamentos relacionados, y un método para la predicción de la evolución clínica del tratamiento de cánceres sólidos y/o metástasis de los mismos |
| EP3194972B1 (en) * | 2014-09-17 | 2021-04-14 | Merck Patent GmbH | A method of treating bone metastasis diseases, medicaments therefore, and a method of predicting the clinical outcome of treating bone metastasis diseases |
| AU2015328411C1 (en) * | 2014-10-06 | 2022-03-03 | Dana-Farber Cancer Institute, Inc. | Angiopoietin-2 biomarkers predictive of anti-immune checkpoint response |
| BR112017010788A2 (pt) * | 2014-12-23 | 2017-12-26 | Genentech Inc | métodos de identificação de um paciente com câncer e de identificação de um paciente que sofre de câncer que pode beneficiar da administração de um antagonista de vegf, método de tratamento de um paciente com câncer e método para determinar o estágio de câncer de ovário |
| RU2019119858A (ru) * | 2016-12-01 | 2021-01-14 | Сантен Фармасьютикал Ко., Лтд. | Способ прогнозирования отвечаемости пациента с влажной amd на анти-vegf терапию |
| KR20200005540A (ko) * | 2017-04-14 | 2020-01-15 | 제넨테크, 인크. | 암의 진단 및 치료 방법 |
| US12070489B2 (en) | 2018-12-12 | 2024-08-27 | Rappaport Family Institute For Research In The Medical Sciences | Method of treating cancer with a cancer therapy in combination with another therapeutic agent |
| US12016900B2 (en) | 2017-06-04 | 2024-06-25 | Rappaport Family Institute For Research In The Medical Sciences | Method of treating cancer with an immune checkpoint inhibitor in combination with another therapeutic agent |
| CA3066053A1 (en) | 2017-06-04 | 2018-12-13 | Rappaport Family Institute For Research In The Medical Sciences | Method of predicting personalized response to cancer treatment with immune checkpoint inhibitors and kits therefor |
| RU2701356C1 (ru) * | 2018-09-18 | 2019-09-25 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Способ диагностики рака молочной железы с экспрессией рецептора Her2/neu на мембране опухолевых клеток |
| US11793889B2 (en) * | 2018-09-24 | 2023-10-24 | Kinase Pharma Inc. | Methods for selective kinase inhibition by endogenously produced antagonists of one or more kinases |
| CN110714078B (zh) * | 2019-09-29 | 2021-11-30 | 浙江大学 | 一种用于ii期结直肠癌复发预测的标记基因及应用 |
| GB202007099D0 (en) * | 2020-05-14 | 2020-07-01 | Kymab Ltd | Tumour biomarkers for immunotherapy |
| EP4099219A1 (en) * | 2021-06-02 | 2022-12-07 | Siemens Healthcare GmbH | Method and device for determining presence of tumor |
| CA3227993A1 (en) | 2021-08-11 | 2023-02-16 | OncoHost Ltd. | Predicting patient response |
| CN115840046A (zh) * | 2022-08-17 | 2023-03-24 | 中国药科大学 | 一种鉴别anti-VEGF抗体获得性耐药的蛋白聚糖ESM1生物学标记物及其应用 |
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| US4892538A (en) | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
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| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
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| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
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- 2013-03-14 HK HK15101498.8A patent/HK1200739A1/xx unknown
- 2013-03-14 KR KR1020147028045A patent/KR20140142719A/ko not_active Ceased
- 2013-03-14 AU AU2013240234A patent/AU2013240234B2/en not_active Ceased
- 2013-03-14 CA CA2867588A patent/CA2867588A1/en not_active Abandoned
- 2013-03-14 CN CN201380023737.9A patent/CN104271157A/zh active Pending
- 2013-03-14 SG SG10201509939PA patent/SG10201509939PA/en unknown
- 2013-03-14 US US14/388,565 patent/US20150056190A1/en not_active Abandoned
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| Publication number | Publication date |
|---|---|
| JP2018075015A (ja) | 2018-05-17 |
| US20150056190A1 (en) | 2015-02-26 |
| WO2013148288A1 (en) | 2013-10-03 |
| RU2014143805A (ru) | 2016-05-27 |
| AU2017204592A1 (en) | 2017-07-27 |
| SG11201406184XA (en) | 2014-10-30 |
| CA2867588A1 (en) | 2013-10-03 |
| BR112014024219A8 (pt) | 2017-07-25 |
| BR112014024219A2 (https=) | 2017-06-20 |
| AU2013240234B2 (en) | 2017-04-27 |
| AU2013240234A1 (en) | 2014-10-09 |
| HK1200739A1 (en) | 2015-08-14 |
| IL234678A0 (en) | 2014-11-30 |
| RU2666627C2 (ru) | 2018-09-11 |
| CN104271157A (zh) | 2015-01-07 |
| EP2830661A4 (en) | 2016-05-18 |
| MX2014011582A (es) | 2014-11-21 |
| KR20140142719A (ko) | 2014-12-12 |
| EP2830661A1 (en) | 2015-02-04 |
| SG10201509939PA (en) | 2016-01-28 |
| JP2015516806A (ja) | 2015-06-18 |
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