JP6329553B2 - Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー - Google Patents

Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー Download PDF

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JP6329553B2
JP6329553B2 JP2015535149A JP2015535149A JP6329553B2 JP 6329553 B2 JP6329553 B2 JP 6329553B2 JP 2015535149 A JP2015535149 A JP 2015535149A JP 2015535149 A JP2015535149 A JP 2015535149A JP 6329553 B2 JP6329553 B2 JP 6329553B2
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ibs
bacterial antigen
antibody
level
markers
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JP2015533213A5 (enExample
JP2015533213A (ja
Inventor
シャラット シン,
シャラット シン,
リン, ニコラス チ‐クワン
リン, ニコラス チ‐クワン
シュイ‐ロン ワン,
シュイ‐ロン ワン,
フレッド プリンセン,
フレッド プリンセン,
ステファン ウェスティン,
ステファン ウェスティン,
スティーブン ロックトン,
スティーブン ロックトン,
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Nestec SA
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Nestec SA
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
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  • Biochemistry (AREA)
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  • Pathology (AREA)
  • Biotechnology (AREA)
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  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2015535149A 2012-10-05 2013-10-01 Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー Expired - Fee Related JP6329553B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261710574P 2012-10-05 2012-10-05
US61/710,574 2012-10-05
US201361871853P 2013-08-29 2013-08-29
US61/871,853 2013-08-29
PCT/IB2013/059045 WO2014053996A2 (en) 2012-10-05 2013-10-01 Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs

Publications (3)

Publication Number Publication Date
JP2015533213A JP2015533213A (ja) 2015-11-19
JP2015533213A5 JP2015533213A5 (enExample) 2016-11-24
JP6329553B2 true JP6329553B2 (ja) 2018-05-23

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JP2015535149A Expired - Fee Related JP6329553B2 (ja) 2012-10-05 2013-10-01 Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー

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US (1) US10184940B2 (enExample)
EP (1) EP2904395B1 (enExample)
JP (1) JP6329553B2 (enExample)
CN (1) CN104884959B (enExample)
AU (1) AU2013326133B2 (enExample)
CA (1) CA2886991A1 (enExample)
MX (1) MX360479B (enExample)
SG (2) SG11201502641YA (enExample)
WO (1) WO2014053996A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0720250D0 (en) * 2007-10-17 2007-11-28 Univ Edinburgh Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof
US20160096819A1 (en) * 2013-05-17 2016-04-07 Basf Se Process for preparing n-substituted 1h-pyrazole-5-carboxylic acid compounds and derivatives thereof
RU2015155552A (ru) 2013-05-24 2017-06-27 Нестек С.А. Путеспецифические способы прогнозирования диагноза синдрома раздраженного кишечника
WO2017079653A2 (en) 2015-11-06 2017-05-11 Vetica Labs, Inc. Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals
EP3421616A1 (en) * 2017-06-29 2019-01-02 Tata Consultancy Services Limited Method and system for monitoring the gut health of an individual
CN111432825A (zh) * 2017-10-03 2020-07-17 赛里斯治疗公司 色胺代谢的操纵
JP6533930B1 (ja) * 2018-08-23 2019-06-26 一般社団法人日本農業フロンティア開発機構 疾病評価指標算出方法、装置、システム、及び、プログラム、並びに、疾病評価指標を算出するためのモデル作成方法。
US11884958B2 (en) 2019-04-30 2024-01-30 Mayo Foundation For Medical Education And Research Assessing and treating functional gastrointestinal disorders
WO2025071560A1 (en) * 2023-09-28 2025-04-03 Rutgers, The State University Of New Jersey Methods of diagnosing b cell malignancies, detecting b cell malignancy relapse, and treating thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003298703A1 (en) * 2002-11-22 2004-06-18 Emory University Diagnostic tests and methods for diagnosing inflammatory bowel disease
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7943328B1 (en) * 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20100094560A1 (en) * 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
WO2011027971A2 (ko) * 2009-09-01 2011-03-10 주식회사이언메딕스 장내 공생 세균유래 세포밖 소포체, 및 이를 이용한 질병모델, 백신, 후보 약물 탐색 방법, 및 진단 방법
EP2494074A4 (en) * 2009-10-30 2013-06-12 Nestec Sa METHOD FOR DIAGNOSING IRRITATION SYNDROME

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Publication number Publication date
MX360479B (es) 2018-11-05
EP2904395A2 (en) 2015-08-12
SG10201702773QA (en) 2017-06-29
US10184940B2 (en) 2019-01-22
EP2904395B1 (en) 2018-09-05
WO2014053996A3 (en) 2014-05-30
CA2886991A1 (en) 2014-04-10
SG11201502641YA (en) 2015-05-28
CN104884959A (zh) 2015-09-02
AU2013326133B2 (en) 2019-07-04
JP2015533213A (ja) 2015-11-19
CN104884959B (zh) 2017-12-01
US20150346200A1 (en) 2015-12-03
MX2015004271A (es) 2015-08-14
HK1213050A1 (en) 2016-06-24
WO2014053996A2 (en) 2014-04-10
AU2013326133A1 (en) 2015-04-23

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