JP6310922B2 - プログラム可能な移植片、および骨構造を修復するためにプログラム可能な移植片を用いる方法 - Google Patents
プログラム可能な移植片、および骨構造を修復するためにプログラム可能な移植片を用いる方法 Download PDFInfo
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- JP6310922B2 JP6310922B2 JP2015533302A JP2015533302A JP6310922B2 JP 6310922 B2 JP6310922 B2 JP 6310922B2 JP 2015533302 A JP2015533302 A JP 2015533302A JP 2015533302 A JP2015533302 A JP 2015533302A JP 6310922 B2 JP6310922 B2 JP 6310922B2
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
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-
- A—HUMAN NECESSITIES
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- A61F2310/00005—The prosthesis being constructed from a particular material
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-
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- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
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- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
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-
- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00598—Coating or prosthesis-covering structure made of compounds based on metal oxides or hydroxides
-
- A—HUMAN NECESSITIES
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- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
Description
Claims (23)
- 骨構造と境界を接するための移植片であって、前記移植片は、
節点で接合された複数の支柱を備える網状構造であって、前記網状構造はヒトの骨組織と境界を接するように構成される、網状構造
を備え、
前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記網状構造が骨と接触するときに、前記支柱の少なくとも一部が接着された骨芽細胞内に微小歪みを生成するようにあらかじめ決定され、前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記支柱の少なくとも一部が500με〜2000μεの微小歪みを接着された骨芽細胞内に生成するようにあらかじめ決定される、移植片。 - 前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記支柱が、負荷下において、接着された骨芽細胞内に微小歪みを生成するようにあらかじめ決定され、前記微小歪みは、骨形成反応を刺激する範囲内にある、請求項1に記載の移植片。
- 前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記支柱の少なくとも一部が1000με〜1500μεの微小歪みを接着された骨芽細胞内に生成するようにあらかじめ決定される、請求項1に記載の移植片。
- 前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記支柱の少なくとも一部が、接着された骨芽細胞の長さを0.05%〜0.2%で変化させるようにあらかじめ決定される、請求項1に記載の移植片。
- 前記支柱は、1mm〜20mmの長さを有し、前記支柱の直径は、前記網状構造が骨と接触するときに、前記支柱が接着された骨芽細胞の長さを0.05%〜0.2%で変化させるようにあらかじめ決定される、請求項1に記載の移植片。
- 前記網状構造は、2つ以上の平面トラス単位を備える空間トラスを含む、請求項1に記載の移植片。
- 前記平面トラス単位の1つ以上は、三角構成において3つの直線状の支柱および3つの節点を有する1つ以上の平面三角トラス単位を備える、請求項6に記載の移植片。
- 前記平面トラス単位の1つ以上は互いに連結され、そのため、1つ以上の平面トラス単位が、前記1つ以上の平面トラス単位と少なくとも1つの支柱を共有する平面トラス単位の平面に平行でない平面に存在する、請求項6に記載の移植片。
- 前記平面トラス単位の1つ以上は、第2の平面三角トラス単位に連結された第1の平面三角トラス単位を備え、第1および第2の平面三角トラス単位は、それぞれの平面三角トラス単位の頂端を画定する単一の節点と対向して連結される、請求項6に記載の移植片。
- 前記支柱のうち少なくともいくつかは、異なる対応する角度を有する2つの異なる三角平面トラス単位により共有される少なくとも1つの節点を有する三角トラスを画定する、請求項1に記載の移植片。
- 骨構造と境界を接するための移植片であって、前記移植片は、
節点で接合された複数の支柱を備える網状構造であって、前記網状構造はヒトの骨組織と境界を接するように構成され、前記網状構造は第1の骨接触表面および第2の骨接触表面を備える、網状構造
を備え、
空間トラスを含む支柱の第1の部分は、空間トラスを含む支柱の第2の部分とは異なる物理的性質を有し、前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記支柱の少なくとも一部が500με〜2000μεの微小歪みを接着された骨芽細胞内に生成するようにあらかじめ決定される、移植片。 - 前記空間トラスを含む支柱の第1の部分は、前記空間トラスを含む支柱の第2の部分とは異なる変形強度を有する、請求項11に記載の移植片。
- 前記空間トラスは、前記第1の骨接触表面から前記第2の骨接触表面に延在する1つ以上の中央支柱を備え、前記中央支柱は周囲の支柱よりも高い変形強度を有する、請求項11に記載の移植片。
- 前記空間トラスは、前記第1の骨接触表面および/または前記第2の骨接触表面に平行に延在する1つ以上の縦支柱を備え、前記縦支柱は周囲の支柱よりも高い変形強度を有する、請求項11に記載の移植片。
- 前記空間トラスは、前記第1の骨接触表面から前記第2の骨接触表面に延在する1つ以上の中央支柱を備え、前記中央支柱は周囲の支柱よりも低い変形強度を有する、請求項11に記載の移植片。
- 前記空間トラスは、前記第1の骨接触表面および/または前記第2の骨接触表面に平行に延在する1つ以上の縦支柱を備え、前記縦支柱は周囲の支柱よりも低い変形強度を有する、請求項11に記載の移植片。
- 前記支柱の第1の部分の直径は、前記支柱の第2の部分の直径より大きい、請求項11に記載の移植片。
- 前記支柱の第1の部分は、前記支柱の第2の部分を形成するために使用される材料とは異なる材料から形成される、請求項11に記載の移植片。
- 前記支柱の第1の部分は、前記支柱の第2の部分の直径とは異なる直径を有する、請求項11に記載の移植片。
- 前記支柱の第1の部分は、前記支柱の第2の部分の密度とは異なる密度を有する、請求項11に記載の移植片。
- 前記支柱の第1の部分は、前記支柱の第2の部分の有孔率とは異なる有孔率を有する、請求項11に記載の移植片。
- 前記支柱のうち少なくともいくつかは、異なる対応する角度を有する2つの異なる三角平面トラス単位により共有される少なくとも1つの節点を有する三角トラスを画定する、請求項11に記載の移植片。
- 骨構造と境界を接するための移植片であって、前記移植片は、
節点で接合された複数の支柱を備える網状構造であって、支柱の第1の部分が、前記支柱の第2の部分とは異なる物理的性質を有する、網状構造
を備え、
前記支柱の直径および/または長さ、ならびに/あるいは前記網状構造の密度は、前記支柱の少なくとも一部が500με〜2000μεの微小歪みを接着された骨芽細胞内に生成するようにあらかじめ決定される、移植片。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261705403P | 2012-09-25 | 2012-09-25 | |
US61/705,403 | 2012-09-25 | ||
US201361801597P | 2013-03-15 | 2013-03-15 | |
US61/801,597 | 2013-03-15 | ||
PCT/US2013/061725 WO2014052477A1 (en) | 2012-09-25 | 2013-09-25 | Programmable implants and methods of using programmable implants to repair bone structures |
Publications (2)
Publication Number | Publication Date |
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JP2015529150A JP2015529150A (ja) | 2015-10-05 |
JP6310922B2 true JP6310922B2 (ja) | 2018-04-11 |
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ID=50388938
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JP2015533302A Active JP6310922B2 (ja) | 2012-09-25 | 2013-09-25 | プログラム可能な移植片、および骨構造を修復するためにプログラム可能な移植片を用いる方法 |
Country Status (8)
Country | Link |
---|---|
US (7) | US9271845B2 (ja) |
EP (1) | EP2900181A4 (ja) |
JP (1) | JP6310922B2 (ja) |
KR (1) | KR20150060828A (ja) |
CN (1) | CN104780870B (ja) |
AU (1) | AU2013323602B2 (ja) |
CA (1) | CA2889063C (ja) |
WO (1) | WO2014052477A1 (ja) |
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- 2013-09-25 KR KR1020157010324A patent/KR20150060828A/ko active IP Right Grant
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JP2015529150A (ja) | 2015-10-05 |
KR20150060828A (ko) | 2015-06-03 |
US9549823B2 (en) | 2017-01-24 |
US20160287405A1 (en) | 2016-10-06 |
US10849756B2 (en) | 2020-12-01 |
CN104780870A (zh) | 2015-07-15 |
US20160287389A1 (en) | 2016-10-06 |
US9271845B2 (en) | 2016-03-01 |
US20160287388A1 (en) | 2016-10-06 |
US9757235B2 (en) | 2017-09-12 |
CA2889063A1 (en) | 2014-04-03 |
US20170360563A1 (en) | 2017-12-21 |
CA2889063C (en) | 2021-10-26 |
US20160287404A1 (en) | 2016-10-06 |
US20140121776A1 (en) | 2014-05-01 |
AU2013323602A1 (en) | 2015-04-16 |
WO2014052477A1 (en) | 2014-04-03 |
US9572669B2 (en) | 2017-02-21 |
AU2013323602B2 (en) | 2018-02-22 |
US20190060077A1 (en) | 2019-02-28 |
CN104780870B (zh) | 2018-03-02 |
US9987137B2 (en) | 2018-06-05 |
EP2900181A4 (en) | 2016-05-18 |
EP2900181A1 (en) | 2015-08-05 |
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