JP6301832B2 - 骨間隙欠陥を処置する方法 - Google Patents

骨間隙欠陥を処置する方法 Download PDF

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JP6301832B2
JP6301832B2 JP2014524076A JP2014524076A JP6301832B2 JP 6301832 B2 JP6301832 B2 JP 6301832B2 JP 2014524076 A JP2014524076 A JP 2014524076A JP 2014524076 A JP2014524076 A JP 2014524076A JP 6301832 B2 JP6301832 B2 JP 6301832B2
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sclerostin
seq
bone
antibody
weeks
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JP2014521692A (ja
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リー，シャオドン
ケ，フア，ズー
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アムジエン・インコーポレーテツド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014524076A 2011-08-04 2012-08-02 骨間隙欠陥を処置する方法 Active JP6301832B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161515191P 2011-08-04 2011-08-04
US61/515,191 2011-08-04
PCT/US2012/049331 WO2013019954A1 (en) 2011-08-04 2012-08-02 Method for treating bone gap defects

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017107279A Division JP2017214374A (ja) 2011-08-04 2017-05-31 骨間隙欠陥を処置する方法

Publications (2)

Publication Number Publication Date
JP2014521692A JP2014521692A (ja) 2014-08-28
JP6301832B2 true JP6301832B2 (ja) 2018-03-28

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Family Applications (4)

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JP2014524076A Active JP6301832B2 (ja) 2011-08-04 2012-08-02 骨間隙欠陥を処置する方法
JP2017107279A Pending JP2017214374A (ja) 2011-08-04 2017-05-31 骨間隙欠陥を処置する方法
JP2019087955A Pending JP2019167348A (ja) 2011-08-04 2019-05-08 骨間隙欠陥を処置する方法
JP2021121157A Pending JP2021183610A (ja) 2011-08-04 2021-07-26 骨間隙欠陥を処置する方法

Family Applications After (3)

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JP2017107279A Pending JP2017214374A (ja) 2011-08-04 2017-05-31 骨間隙欠陥を処置する方法
JP2019087955A Pending JP2019167348A (ja) 2011-08-04 2019-05-08 骨間隙欠陥を処置する方法
JP2021121157A Pending JP2021183610A (ja) 2011-08-04 2021-07-26 骨間隙欠陥を処置する方法

Country Status (17)

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US (2) US10538584B2 (enExample)
EP (1) EP2739311B9 (enExample)
JP (4) JP6301832B2 (enExample)
AU (1) AU2012290083B2 (enExample)
CA (1) CA2842432C (enExample)
CY (1) CY1120666T1 (enExample)
DK (1) DK2739311T3 (enExample)
ES (1) ES2667554T3 (enExample)
HR (1) HRP20180736T1 (enExample)
HU (1) HUE039786T2 (enExample)
LT (1) LT2739311T (enExample)
MX (1) MX355816B (enExample)
NO (1) NO2739311T3 (enExample)
PL (1) PL2739311T3 (enExample)
PT (1) PT2739311T (enExample)
SI (1) SI2739311T1 (enExample)
WO (1) WO2013019954A1 (enExample)

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Publication number Priority date Publication date Assignee Title
US7592429B2 (en) * 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
TWI636993B (zh) * 2010-10-27 2018-10-01 安美基公司 Ｄｋｋ１抗體及使用方法
UY35148A (es) * 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
WO2015087187A1 (en) * 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
WO2018115879A1 (en) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta
CA3103391A1 (en) 2018-06-13 2019-12-19 Stryker European Operations Limited Bone fragment collector and processor
EP4076290B1 (en) 2019-12-18 2024-07-31 Stryker European Operations Limited Bone fragment collector and processor

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EP2739311B1 (en) 2018-02-21
CY1120666T1 (el) 2019-12-11
HRP20180736T1 (hr) 2018-06-29
JP2014521692A (ja) 2014-08-28
EP2739311B9 (en) 2018-09-19
MX355816B (es) 2018-05-02
MX2014001416A (es) 2014-10-17
ES2667554T9 (es) 2018-10-01
HUE039786T2 (hu) 2019-02-28
PL2739311T3 (pl) 2018-08-31
US10538584B2 (en) 2020-01-21
AU2012290083B2 (en) 2017-07-20
PT2739311T (pt) 2018-03-26
AU2012290083A1 (en) 2014-03-13
EP2739311A1 (en) 2014-06-11
WO2013019954A1 (en) 2013-02-07
NO2739311T3 (enExample) 2018-07-21
DK2739311T3 (en) 2018-04-23
JP2021183610A (ja) 2021-12-02
SI2739311T1 (en) 2018-07-31
JP2017214374A (ja) 2017-12-07
JP2019167348A (ja) 2019-10-03
US20140271654A1 (en) 2014-09-18
LT2739311T (lt) 2018-06-11
CA2842432A1 (en) 2013-02-07
CA2842432C (en) 2022-10-04
ES2667554T3 (es) 2018-05-11
US20200115444A1 (en) 2020-04-16

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