JP6276175B2 - 潜在的有害作用リスクのある患者にＣＤ１９ｘＣＤ３二特異性抗体を投与するための投薬レジメン - Google Patents

潜在的有害作用リスクのある患者にＣＤ１９ｘＣＤ３二特異性抗体を投与するための投薬レジメン Download PDF

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JP6276175B2
JP6276175B2 JP2014506794A JP2014506794A JP6276175B2 JP 6276175 B2 JP6276175 B2 JP 6276175B2 JP 2014506794 A JP2014506794 A JP 2014506794A JP 2014506794 A JP2014506794 A JP 2014506794A JP 6276175 B2 JP6276175 B2 JP 6276175B2
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JP2014513088A (ja
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ディルク ナゴルゼン
ディルク ナゴルゼン
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アムジェン リサーチ （ミュニック） ゲゼルシャフト ミット ベシュレンクテル ハフツング
アムジェン リサーチ （ミュニック） ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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JP2014506794A 2011-04-28 2012-04-30 潜在的有害作用リスクのある患者にＣＤ１９ｘＣＤ３二特異性抗体を投与するための投薬レジメン Active JP6276175B2 (ja)

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US201161479961P 2011-04-28 2011-04-28
US61/479,961 2011-04-28
PCT/EP2012/001857 WO2012146394A1 (en) 2011-04-28 2012-04-30 Dosage regimen for administering a cd19xcd3 bispecific antibody to patients at risk for potential adverse effects

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JP2017194928A Active JP6539709B2 (ja) 2011-04-28 2017-10-05 潜在的有害作用リスクのある患者にＣＤ１９ｘＣＤ３二特異性抗体を投与するための投薬レジメン

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AU2017218919A1 (en) 2017-09-07
KR102147533B1 (ko) 2020-08-25
JP6539709B2 (ja) 2019-07-03
MX354371B (es) 2018-02-28
KR20140043350A (ko) 2014-04-09
EP2701741A1 (en) 2014-03-05
US11579142B2 (en) 2023-02-14
CA2832360A1 (en) 2012-11-01
JP2018046824A (ja) 2018-03-29
MX2013012448A (es) 2014-02-27
KR20200104415A (ko) 2020-09-03
AU2012247762A1 (en) 2013-10-17
US10191034B2 (en) 2019-01-29
CN103648529A (zh) 2014-03-19
KR102345943B1 (ko) 2021-12-31
AU2012247762B2 (en) 2017-07-06
WO2012146394A1 (en) 2012-11-01
CN107303387A (zh) 2017-10-31
EP2701741B1 (en) 2020-06-10
CA2832360C (en) 2022-05-03
US20140199307A1 (en) 2014-07-17
JP2014513088A (ja) 2014-05-29
EP3753572A1 (en) 2020-12-23
ES2806142T3 (es) 2021-02-16

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