JP6250649B2 - シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用 - Google Patents

シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用 Download PDF

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Publication number
JP6250649B2
JP6250649B2 JP2015515159A JP2015515159A JP6250649B2 JP 6250649 B2 JP6250649 B2 JP 6250649B2 JP 2015515159 A JP2015515159 A JP 2015515159A JP 2015515159 A JP2015515159 A JP 2015515159A JP 6250649 B2 JP6250649 B2 JP 6250649B2
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sbv
sequence
seq
vaccine composition
cells
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JP2015519367A (ja
JP2015519367A5 (enExample
Inventor
ヴェルコ ニコリン
ヴェルコ ニコリン
コンラート シュタードラー
コンラート シュタードラー
アクセル リシェウスキー
アクセル リシェウスキー
アレクサンダー ブリクス
アレクサンダー ブリクス
ジェフリー ピー ニッテル
ジェフリー ピー ニッテル
カタリーナ ヘートヴィヒ テプファー
カタリーナ ヘートヴィヒ テプファー
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Boehringer Ingelheim Vetmedica GmbH
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Boehringer Ingelheim Vetmedica GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
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    • C12N2760/12011Bunyaviridae
    • C12N2760/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12061Methods of inactivation or attenuation
    • C12N2760/12063Methods of inactivation or attenuation by chemical treatment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2015515159A 2012-06-01 2013-05-29 シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用 Expired - Fee Related JP6250649B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12170631 2012-06-01
EP12170631.1 2012-06-01
EP13157875 2013-03-05
EP13157875.9 2013-03-05
PCT/US2013/043146 WO2013181270A1 (en) 2012-06-01 2013-05-29 Schmallenberg virus (sbv) vaccine, methods of production, and uses thereof

Publications (3)

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JP2015519367A JP2015519367A (ja) 2015-07-09
JP2015519367A5 JP2015519367A5 (enExample) 2016-07-14
JP6250649B2 true JP6250649B2 (ja) 2017-12-20

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JP2015515159A Expired - Fee Related JP6250649B2 (ja) 2012-06-01 2013-05-29 シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用

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US (2) US9370562B2 (enExample)
EP (1) EP2855513B1 (enExample)
JP (1) JP6250649B2 (enExample)
CN (1) CN104350066B (enExample)
AR (1) AR091240A1 (enExample)
AU (1) AU2013267453C1 (enExample)
BR (1) BR112014029515A2 (enExample)
CA (1) CA2872961A1 (enExample)
DK (1) DK2855513T3 (enExample)
EA (1) EA034543B1 (enExample)
ES (1) ES2617351T3 (enExample)
IN (1) IN2014DN08927A (enExample)
MX (1) MX363044B (enExample)
PL (1) PL2855513T3 (enExample)
SG (1) SG11201407619SA (enExample)
UY (1) UY34840A (enExample)
WO (1) WO2013181270A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6250649B2 (ja) 2012-06-01 2017-12-20 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用
EP2855512B1 (en) 2012-06-01 2018-02-28 Boehringer Ingelheim Vetmedica GmbH Genomic sequences of schmallenberg virus and uses thereof
HK1216006A1 (zh) * 2013-03-12 2016-10-07 Boehringer Ingelheim Animal Health USA Inc. 反向遺傳學施馬倫貝格病毒疫苗組合物,和其使用方法
CN104232587B (zh) * 2014-09-02 2016-08-17 中国检验检疫科学研究院 稳定表达施马伦贝格病毒核衣壳蛋白的细胞系及其应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0811736B2 (ja) * 1986-08-07 1996-02-07 財団法人化学及血清療法研究所 牛流行熱・イバラキ病・アカバネ病3種混合不活化ワクチン
GB9110808D0 (en) 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
US6114108A (en) 1995-08-29 2000-09-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of viral nucleic acids
US20080226682A1 (en) * 2007-03-13 2008-09-18 Peros Systems Technologies, Inc. Immunoactive Compositions for Improved Oral Delivery of Vaccines and Therapeutic Agents
EP2062594A1 (en) 2007-11-21 2009-05-27 Wyeth Farma, S.A. Bluetongue virus vaccine and immunogenic compositions, methods of use and methods of producing same
JP6250649B2 (ja) 2012-06-01 2017-12-20 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用
EP2855512B1 (en) 2012-06-01 2018-02-28 Boehringer Ingelheim Vetmedica GmbH Genomic sequences of schmallenberg virus and uses thereof

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Publication number Publication date
US9872897B2 (en) 2018-01-23
AU2013267453A1 (en) 2014-11-13
EP2855513A1 (en) 2015-04-08
ES2617351T3 (es) 2017-06-16
JP2015519367A (ja) 2015-07-09
EA201401352A1 (ru) 2015-05-29
CN104350066A (zh) 2015-02-11
AU2013267453B2 (en) 2017-04-06
US9370562B2 (en) 2016-06-21
UY34840A (es) 2013-12-31
EP2855513B1 (en) 2016-12-07
PL2855513T3 (pl) 2017-05-31
WO2013181270A1 (en) 2013-12-05
EA034543B1 (ru) 2020-02-19
DK2855513T3 (en) 2017-03-13
US20160250317A1 (en) 2016-09-01
AR091240A1 (es) 2015-01-21
BR112014029515A2 (pt) 2017-07-25
SG11201407619SA (en) 2014-12-30
US20130323277A1 (en) 2013-12-05
IN2014DN08927A (enExample) 2015-05-22
CN104350066B (zh) 2018-06-19
AU2013267453C1 (en) 2017-08-10
MX363044B (es) 2019-03-06
CA2872961A1 (en) 2013-12-05
MX2014014521A (es) 2015-02-24

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