EA034543B1 - Иммуногенная композиция (вакцина) против вируса шмалленберга (sbv), способ ее получения и способ индукции иммунного ответа против sbv - Google Patents

Иммуногенная композиция (вакцина) против вируса шмалленберга (sbv), способ ее получения и способ индукции иммунного ответа против sbv Download PDF

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Publication number
EA034543B1
EA034543B1 EA201401352A EA201401352A EA034543B1 EA 034543 B1 EA034543 B1 EA 034543B1 EA 201401352 A EA201401352 A EA 201401352A EA 201401352 A EA201401352 A EA 201401352A EA 034543 B1 EA034543 B1 EA 034543B1
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Prior art keywords
sbv
seq
cells
nucleotide sequence
immunogenic composition
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EA201401352A
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English (en)
Russian (ru)
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EA201401352A1 (ru
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Велько Николин
Конрад Штадлер
Аксель Лишевски
Александер Брикс
Джеффри П. Ниттел
Катарина Хедвиг Тёпфер
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Бёрингер Ингельхайм Ветмедика Гмбх
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Publication of EA201401352A1 publication Critical patent/EA201401352A1/ru
Publication of EA034543B1 publication Critical patent/EA034543B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
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    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011Details
    • C12N2760/12011Bunyaviridae
    • C12N2760/12061Methods of inactivation or attenuation
    • C12N2760/12063Methods of inactivation or attenuation by chemical treatment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EA201401352A 2012-06-01 2013-05-29 Иммуногенная композиция (вакцина) против вируса шмалленберга (sbv), способ ее получения и способ индукции иммунного ответа против sbv EA034543B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12170631 2012-06-01
EP13157875 2013-03-05
PCT/US2013/043146 WO2013181270A1 (en) 2012-06-01 2013-05-29 Schmallenberg virus (sbv) vaccine, methods of production, and uses thereof

Publications (2)

Publication Number Publication Date
EA201401352A1 EA201401352A1 (ru) 2015-05-29
EA034543B1 true EA034543B1 (ru) 2020-02-19

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EA201401352A EA034543B1 (ru) 2012-06-01 2013-05-29 Иммуногенная композиция (вакцина) против вируса шмалленберга (sbv), способ ее получения и способ индукции иммунного ответа против sbv

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US (2) US9370562B2 (enExample)
EP (1) EP2855513B1 (enExample)
JP (1) JP6250649B2 (enExample)
CN (1) CN104350066B (enExample)
AR (1) AR091240A1 (enExample)
AU (1) AU2013267453C1 (enExample)
BR (1) BR112014029515A2 (enExample)
CA (1) CA2872961A1 (enExample)
DK (1) DK2855513T3 (enExample)
EA (1) EA034543B1 (enExample)
ES (1) ES2617351T3 (enExample)
IN (1) IN2014DN08927A (enExample)
MX (1) MX363044B (enExample)
PL (1) PL2855513T3 (enExample)
SG (1) SG11201407619SA (enExample)
UY (1) UY34840A (enExample)
WO (1) WO2013181270A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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JP6250649B2 (ja) 2012-06-01 2017-12-20 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用
EP2855512B1 (en) 2012-06-01 2018-02-28 Boehringer Ingelheim Vetmedica GmbH Genomic sequences of schmallenberg virus and uses thereof
HK1216006A1 (zh) * 2013-03-12 2016-10-07 Boehringer Ingelheim Animal Health USA Inc. 反向遺傳學施馬倫貝格病毒疫苗組合物,和其使用方法
CN104232587B (zh) * 2014-09-02 2016-08-17 中国检验检疫科学研究院 稳定表达施马伦贝格病毒核衣壳蛋白的细胞系及其应用

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GB9110808D0 (en) 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
US6114108A (en) 1995-08-29 2000-09-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of viral nucleic acids
US20080226682A1 (en) * 2007-03-13 2008-09-18 Peros Systems Technologies, Inc. Immunoactive Compositions for Improved Oral Delivery of Vaccines and Therapeutic Agents
EP2062594A1 (en) 2007-11-21 2009-05-27 Wyeth Farma, S.A. Bluetongue virus vaccine and immunogenic compositions, methods of use and methods of producing same
JP6250649B2 (ja) 2012-06-01 2017-12-20 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH シュマレンベルクウイルス(sbv)ワクチン、その製造方法及び使用
EP2855512B1 (en) 2012-06-01 2018-02-28 Boehringer Ingelheim Vetmedica GmbH Genomic sequences of schmallenberg virus and uses thereof

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BERND HOFFMANN, SCHEUCH MATTHIAS, H�PER DIRK, JUNGBLUT RALF, HOLSTEG MARK, SCHIRRMEIER HORST, ESCHBAUMER MICHAEL, GOLLER KATJA V.,: "Novel Orthobunyavirus in Cattle, Europe, 2011", EMERGING INFECTIOUS DISEASES, U.S. NATIONAL CENTER FOR INFECTIOUS DISEASES, vol. 18, no. 3, pages 469 - 472, XP055054135, ISSN: 10806040, DOI: 10.3201/eid1803.111905 *
ELLIOTT R M, BLAKQORI G, VAN KNIPPENBERG I C, KOUDRIAKOVA E, LI P, MCLEES A, SHI X, SZEMIEL A M: "Establishment of a reverse genetics system for Schmallenberg virus, a newly emerged orthobunyavirus in Europe.", JOURNAL OF GENERAL VIROLOGY., SOCIETY FOR GENERAL MICROBIOLOGY, SPENCERS WOOD., GB, vol. 94, no. Part 4, 1 April 2013 (2013-04-01), GB, pages 851 - 859, XP002700255, ISSN: 0022-1317, DOI: 10.1099/vir.0.049981-0 *
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Also Published As

Publication number Publication date
US9872897B2 (en) 2018-01-23
AU2013267453A1 (en) 2014-11-13
EP2855513A1 (en) 2015-04-08
ES2617351T3 (es) 2017-06-16
JP2015519367A (ja) 2015-07-09
JP6250649B2 (ja) 2017-12-20
EA201401352A1 (ru) 2015-05-29
CN104350066A (zh) 2015-02-11
AU2013267453B2 (en) 2017-04-06
US9370562B2 (en) 2016-06-21
UY34840A (es) 2013-12-31
EP2855513B1 (en) 2016-12-07
PL2855513T3 (pl) 2017-05-31
WO2013181270A1 (en) 2013-12-05
DK2855513T3 (en) 2017-03-13
US20160250317A1 (en) 2016-09-01
AR091240A1 (es) 2015-01-21
BR112014029515A2 (pt) 2017-07-25
SG11201407619SA (en) 2014-12-30
US20130323277A1 (en) 2013-12-05
IN2014DN08927A (enExample) 2015-05-22
CN104350066B (zh) 2018-06-19
AU2013267453C1 (en) 2017-08-10
MX363044B (es) 2019-03-06
CA2872961A1 (en) 2013-12-05
MX2014014521A (es) 2015-02-24

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