JP6223444B2 - 蛋白質‐脂質複合体を用いた抗生物質治療の増強 - Google Patents

蛋白質‐脂質複合体を用いた抗生物質治療の増強 Download PDF

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JP6223444B2
JP6223444B2 JP2015520705A JP2015520705A JP6223444B2 JP 6223444 B2 JP6223444 B2 JP 6223444B2 JP 2015520705 A JP2015520705 A JP 2015520705A JP 2015520705 A JP2015520705 A JP 2015520705A JP 6223444 B2 JP6223444 B2 JP 6223444B2
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alafac
antibiotics
antibiotic
gentamicin
penicillin
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JP2015522040A5 (enExample
JP2015522040A (ja
Inventor
ハッカンソン,アンダース,ピー.
マークス,ローラ,アール.
ハッカンソン,ヘイズライン
Original Assignee
ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク
ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
JP2015520705A 2012-07-05 2013-07-05 蛋白質‐脂質複合体を用いた抗生物質治療の増強 Expired - Fee Related JP6223444B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261668390P 2012-07-05 2012-07-05
US61/668,390 2012-07-05
PCT/US2013/049437 WO2014008465A2 (en) 2012-07-05 2013-07-05 Potentiation of antibiotic treatment with a protein-lipid complex

Publications (3)

Publication Number Publication Date
JP2015522040A JP2015522040A (ja) 2015-08-03
JP2015522040A5 JP2015522040A5 (enExample) 2016-08-25
JP6223444B2 true JP6223444B2 (ja) 2017-11-01

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JP2015520705A Expired - Fee Related JP6223444B2 (ja) 2012-07-05 2013-07-05 蛋白質‐脂質複合体を用いた抗生物質治療の増強

Country Status (5)

Country Link
US (1) US9526766B2 (enExample)
EP (1) EP2869831A4 (enExample)
JP (1) JP6223444B2 (enExample)
CA (1) CA2878292A1 (enExample)
WO (1) WO2014008465A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8513305B2 (en) 2007-05-14 2013-08-20 Research Foundation Of State University Of New York Induction of a physiological dispersion response in bacterial cells in a biofilm
CN104068123B (zh) * 2014-06-26 2016-06-22 南京医科大学 一种乳白蛋白和油酸复合物抗肿瘤的保健饮料及其制备方法
WO2018070874A1 (en) * 2016-10-12 2018-04-19 Rijksuniversiteit Groningen Means and methods for reducing or avoiding antibiotic resistance and spread of virulence in human pathogens
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1032596T3 (da) 1997-11-21 2007-09-10 Nya Hamlet Pharma Ab Fremgangsmåde til fremstilling af lactalbumin
GB9725126D0 (en) 1997-11-27 1998-01-28 Svanborg Catharina Therapeutic agents
CN101588820A (zh) * 2006-11-17 2009-11-25 尼亚哈姆雷特药品公司 α-乳清蛋白组合物
CA2784826A1 (en) * 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for stable liquid drug formulations

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Publication number Publication date
EP2869831A2 (en) 2015-05-13
WO2014008465A3 (en) 2014-07-31
EP2869831A4 (en) 2016-04-06
CA2878292A1 (en) 2014-01-09
US20150148286A1 (en) 2015-05-28
JP2015522040A (ja) 2015-08-03
US9526766B2 (en) 2016-12-27
WO2014008465A2 (en) 2014-01-09

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