JP6180515B2 - ブロモクリプチン製剤 - Google Patents

ブロモクリプチン製剤 Download PDF

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Publication number
JP6180515B2
JP6180515B2 JP2015510364A JP2015510364A JP6180515B2 JP 6180515 B2 JP6180515 B2 JP 6180515B2 JP 2015510364 A JP2015510364 A JP 2015510364A JP 2015510364 A JP2015510364 A JP 2015510364A JP 6180515 B2 JP6180515 B2 JP 6180515B2
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Prior art keywords
bromocriptine
bromocriptine mesylate
less
tablet
formulation
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JP2015510364A
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Japanese (ja)
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JP2015515984A5 (enExample
JP2015515984A (ja
Inventor
エイチ． シンコッタ，アンソニー
エイチ． シンコッタ，アンソニー
マイケル ボウ，クレイグ
マイケル ボウ，クレイグ
クラーク スターンズ，ポール
クラーク スターンズ，ポール
ジーン ウェストン，ローラ
ジーン ウェストン，ローラ
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ヴェロサイエンス，リミテッド・ライアビリティー・カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2015510364A 2012-04-30 2013-04-29 ブロモクリプチン製剤 Active JP6180515B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/460,452 2012-04-30
US13/460,452 US8431155B1 (en) 2012-04-30 2012-04-30 Bromocriptine formulations
PCT/US2013/038655 WO2013165902A1 (en) 2012-04-30 2013-04-29 Bromocriptine formulations

Publications (3)

Publication Number Publication Date
JP2015515984A JP2015515984A (ja) 2015-06-04
JP2015515984A5 JP2015515984A5 (enExample) 2016-06-30
JP6180515B2 true JP6180515B2 (ja) 2017-08-16

Family

ID=48146046

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015510364A Active JP6180515B2 (ja) 2012-04-30 2013-04-29 ブロモクリプチン製剤

Country Status (12)

Country Link
US (11) US8431155B1 (enExample)
EP (4) EP4342536B1 (enExample)
JP (1) JP6180515B2 (enExample)
KR (1) KR101593360B1 (enExample)
AR (1) AR091351A1 (enExample)
AU (3) AU2013256558B2 (enExample)
BR (1) BR112014027087B1 (enExample)
CA (1) CA2872300C (enExample)
ES (3) ES2972198T3 (enExample)
MX (2) MX363670B (enExample)
UY (1) UY34776A (enExample)
WO (1) WO2013165902A1 (enExample)

Families Citing this family (12)

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US20160038424A1 (en) 2016-02-11
AR091351A1 (es) 2015-01-28
EP3620155A1 (en) 2020-03-11
AU2016202572B2 (en) 2018-02-01
AU2013256558A1 (en) 2014-12-18
BR112014027087A2 (pt) 2017-06-27
ES2755081T3 (es) 2020-04-21
EP4342536C0 (en) 2025-10-01
KR101593360B1 (ko) 2016-02-11
US11000522B2 (en) 2021-05-11
EP3620155B1 (en) 2021-10-20
HK1208173A1 (en) 2016-02-26
AU2013256558B2 (en) 2016-01-28
US20170020871A1 (en) 2017-01-26
AU2018203021B2 (en) 2020-02-06
ES2972198T3 (es) 2024-06-11
US20240131026A1 (en) 2024-04-25
EP3960160B1 (en) 2023-12-06
US20180263978A1 (en) 2018-09-20
KR20150006461A (ko) 2015-01-16
US8431155B1 (en) 2013-04-30
US20200276193A1 (en) 2020-09-03
MX363670B (es) 2019-03-29
MX2014013158A (es) 2015-07-14
US20190343833A1 (en) 2019-11-14
WO2013165902A1 (en) 2013-11-07
EP4342536B1 (en) 2025-10-01
US9993474B2 (en) 2018-06-12
AU2018203021A1 (en) 2018-05-24
US9700555B2 (en) 2017-07-11
US8613947B2 (en) 2013-12-24
UY34776A (es) 2013-11-29
ES2902573T3 (es) 2022-03-29
US20170340632A1 (en) 2017-11-30
EP4342536A2 (en) 2024-03-27
AU2016202572A1 (en) 2016-05-19
US20130287848A1 (en) 2013-10-31
US20140187560A1 (en) 2014-07-03
JP2015515984A (ja) 2015-06-04
BR112014027087B1 (pt) 2021-03-02
EP2844229B1 (en) 2019-09-11
US20210228576A1 (en) 2021-07-29
EP4342536A3 (en) 2024-06-26
MX2019003619A (es) 2019-07-18
US9192576B2 (en) 2015-11-24
US11666567B2 (en) 2023-06-06
CA2872300A1 (en) 2013-11-07
US9522117B2 (en) 2016-12-20
US10307421B2 (en) 2019-06-04
EP3960160A1 (en) 2022-03-02
EP2844229A1 (en) 2015-03-11
US10688094B2 (en) 2020-06-23
CA2872300C (en) 2016-08-16

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