BR112014027087A2 - tablete, método para fabricação de um tablete de mesilato de bromocriptina, método para fabricação de um tablete de mesilato de bromocriptina e método de tratamento para melhorar o controle glicêmico de diabetes do tipo 2 em um paciente - Google Patents
tablete, método para fabricação de um tablete de mesilato de bromocriptina, método para fabricação de um tablete de mesilato de bromocriptina e método de tratamento para melhorar o controle glicêmico de diabetes do tipo 2 em um pacienteInfo
- Publication number
- BR112014027087A2 BR112014027087A2 BR112014027087A BR112014027087A BR112014027087A2 BR 112014027087 A2 BR112014027087 A2 BR 112014027087A2 BR 112014027087 A BR112014027087 A BR 112014027087A BR 112014027087 A BR112014027087 A BR 112014027087A BR 112014027087 A2 BR112014027087 A2 BR 112014027087A2
- Authority
- BR
- Brazil
- Prior art keywords
- tablet
- manufacturing
- bromocriptine mesylate
- diabetes
- type
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
resumo tablete, método para fabricação de um tablete de mesilato de bromocriptina, método para fabricação de um tablete de mesilato de bromocriptina e método de tratamento para melhorar o controle glicêmico de diabetes do tipo 2 em um paciente a presente invenção descreve formulações farmacêuticas de mesilato de bromocriptina e métodos para fabricação e uso das referidas formulações. as formulações são úteis para melhorar o controle glicêmico no tratamento do diabetes tipo 2. 1/1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/460,452 US8431155B1 (en) | 2012-04-30 | 2012-04-30 | Bromocriptine formulations |
US13/460,452 | 2012-04-30 | ||
PCT/US2013/038655 WO2013165902A1 (en) | 2012-04-30 | 2013-04-29 | Bromocriptine formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014027087A2 true BR112014027087A2 (pt) | 2017-06-27 |
BR112014027087B1 BR112014027087B1 (pt) | 2021-03-02 |
Family
ID=48146046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014027087-2A BR112014027087B1 (pt) | 2012-04-30 | 2013-04-29 | tablete e método para fabricação de um tablete de mesilato de bromocriptina |
Country Status (13)
Country | Link |
---|---|
US (10) | US8431155B1 (pt) |
EP (4) | EP2844229B1 (pt) |
JP (1) | JP6180515B2 (pt) |
KR (1) | KR101593360B1 (pt) |
AR (1) | AR091351A1 (pt) |
AU (3) | AU2013256558B2 (pt) |
BR (1) | BR112014027087B1 (pt) |
CA (1) | CA2872300C (pt) |
ES (2) | ES2755081T3 (pt) |
HK (1) | HK1208173A1 (pt) |
MX (2) | MX363670B (pt) |
UY (1) | UY34776A (pt) |
WO (1) | WO2013165902A1 (pt) |
Families Citing this family (12)
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US9655865B2 (en) | 2002-07-29 | 2017-05-23 | Veroscience, Llc | Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes |
US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
EP3524248A1 (en) | 2007-06-21 | 2019-08-14 | VeroScience LLC | Method of treating metabolic disorders and depression with dopamine receptor agonists |
US20100035886A1 (en) | 2007-06-21 | 2010-02-11 | Veroscience, Llc | Parenteral formulations of dopamine agonists |
US8741918B2 (en) | 2007-06-21 | 2014-06-03 | Veroscience Llc | Parenteral formulations of dopamine agonists |
US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
US8431155B1 (en) | 2012-04-30 | 2013-04-30 | Veroscience Llc | Bromocriptine formulations |
CN104394846B (zh) | 2012-05-03 | 2018-10-19 | 爱尔兰詹森科学公司 | 用于治疗上呼吸道感染的聚肌苷酸-聚胞苷酸(聚(i:c))配制品 |
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WO2021061818A1 (en) | 2019-09-23 | 2021-04-01 | Veroscience Llc | Method for inducing tumor regression |
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2012
- 2012-04-30 US US13/460,452 patent/US8431155B1/en active Active
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2013
- 2013-02-21 US US13/773,500 patent/US8613947B2/en active Active
- 2013-04-29 EP EP13721874.9A patent/EP2844229B1/en active Active
- 2013-04-29 EP EP19191600.6A patent/EP3620155B1/en active Active
- 2013-04-29 JP JP2015510364A patent/JP6180515B2/ja active Active
- 2013-04-29 BR BR112014027087-2A patent/BR112014027087B1/pt active IP Right Grant
- 2013-04-29 MX MX2014013158A patent/MX363670B/es unknown
- 2013-04-29 EP EP21203207.2A patent/EP3960160B1/en active Active
- 2013-04-29 KR KR1020147033501A patent/KR101593360B1/ko active IP Right Grant
- 2013-04-29 ES ES13721874T patent/ES2755081T3/es active Active
- 2013-04-29 EP EP23214280.2A patent/EP4342536A2/en active Pending
- 2013-04-29 ES ES19191600T patent/ES2902573T3/es active Active
- 2013-04-29 CA CA2872300A patent/CA2872300C/en active Active
- 2013-04-29 AU AU2013256558A patent/AU2013256558B2/en active Active
- 2013-04-29 WO PCT/US2013/038655 patent/WO2013165902A1/en active Application Filing
- 2013-04-30 UY UY0001034776A patent/UY34776A/es not_active Application Discontinuation
- 2013-04-30 AR ARP130101471 patent/AR091351A1/es unknown
- 2013-11-22 US US14/088,269 patent/US9192576B2/en active Active
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2014
- 2014-10-29 MX MX2019003619A patent/MX2019003619A/es unknown
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2015
- 2015-09-10 HK HK15108831.9A patent/HK1208173A1/xx unknown
- 2015-10-22 US US14/920,123 patent/US9522117B2/en active Active
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2016
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- 2016-10-06 US US15/286,826 patent/US9700555B2/en active Active
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