JP6179955B2 - 血小板溶解物の組成物、用途および調製 - Google Patents

血小板溶解物の組成物、用途および調製 Download PDF

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JP6179955B2
JP6179955B2 JP2014518918A JP2014518918A JP6179955B2 JP 6179955 B2 JP6179955 B2 JP 6179955B2 JP 2014518918 A JP2014518918 A JP 2014518918A JP 2014518918 A JP2014518918 A JP 2014518918A JP 6179955 B2 JP6179955 B2 JP 6179955B2
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fibrinogen
cell
cells
platelet
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JP2014522833A5 (https=
JP2014522833A (ja
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ビー コプランド，イアン
ビー コプランド，イアン
ガリポー，ジャック
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Childrens Healthcare of Atlanta Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
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    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Rheumatology (AREA)
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  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
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  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2014518918A 2011-06-27 2012-06-26 血小板溶解物の組成物、用途および調製 Active JP6179955B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161501411P 2011-06-27 2011-06-27
US61/501,411 2011-06-27
US201161547897P 2011-10-17 2011-10-17
US61/547,897 2011-10-17
PCT/US2012/044211 WO2013003356A1 (en) 2011-06-27 2012-06-26 Compositions, uses, and preparation of platelet lysates

Publications (3)

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JP2014522833A JP2014522833A (ja) 2014-09-08
JP2014522833A5 JP2014522833A5 (https=) 2015-08-06
JP6179955B2 true JP6179955B2 (ja) 2017-08-16

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JP2014518918A Active JP6179955B2 (ja) 2011-06-27 2012-06-26 血小板溶解物の組成物、用途および調製

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US (2) US9688959B2 (https=)
EP (1) EP2723354B3 (https=)
JP (1) JP6179955B2 (https=)
CN (2) CN108671224B (https=)
AU (1) AU2012275562B2 (https=)
CA (1) CA2840568C (https=)
ES (1) ES2811085T7 (https=)
WO (1) WO2013003356A1 (https=)

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US10905721B2 (en) 2013-01-28 2021-02-02 Regenexx, Llc. Device and methods for platelet lysis or activation
WO2015031465A1 (en) * 2013-08-27 2015-03-05 Cook General Biotechnology Llc Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same
HK1194912A2 (en) * 2013-09-17 2014-10-24 Bestop Group Holdings Ltd Growth factor concentrate and the use thereof
WO2015148723A1 (en) * 2014-03-25 2015-10-01 Cook Biotech Incorporated Extracellular matrix grafts loaded with exogenous factors
CA2974225C (en) * 2015-01-21 2023-08-08 Edvin TURKOF Platelet concentrate for increase of cell regeneration and cell growth
EP3258945B1 (en) * 2015-02-16 2020-10-07 Nayacure Therapeutics Ltd. Modified blood clots
KR102925966B1 (ko) 2015-05-29 2026-02-10 자디 셀 엘엘씨 미립자 동결건조된 혈소판 용해물 조성물
CN107304412A (zh) * 2016-04-22 2017-10-31 南京医科大学第附属医院 视网膜色素上皮细胞的培养基及其应用
EP3254684B1 (en) 2016-06-08 2019-10-23 Lysatpharma GmbH Human platelet lysate or fraction enriched in human platelet-derived extracellular vesicles, for use in medicine
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IL271436B2 (en) * 2017-06-16 2024-02-01 Centre Hospitalier Regional Et Univ De Lille Chru Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders
ES2985827T3 (es) * 2017-12-22 2024-11-07 Chiesi Farm Spa Células estromales mesenquimales y procedimientos de obtención de células estromales mesenquimales a partir del cordón umbilical
FR3077823B1 (fr) 2018-02-15 2022-01-14 Maco Pharma Sa Procede de preparation d'un lysat plaquettaire irradie
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CN114450066A (zh) 2019-08-16 2022-05-06 塞尔菲乐有限公司 作为抗血小板剂逆转剂的血栓小体
WO2021035205A1 (en) * 2019-08-22 2021-02-25 Awidi Abdalla S Method of preparing a de-fibrinated platelet lysate, and uses of said method
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CN111303270B (zh) * 2020-02-18 2022-04-01 浙江中医药大学 一种利用套装制备血小板生长因子浓集物的方法
EP3881858A1 (en) 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect
CN111569139A (zh) * 2020-05-26 2020-08-25 上海市第六人民医院 一种负载血小板裂解液的自支撑自组装多层膜及其应用
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