ES2811085T7 - Composiciones, usos y preparación de lisados de plaquetas - Google Patents
Composiciones, usos y preparación de lisados de plaquetas Download PDFInfo
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- ES2811085T7 ES2811085T7 ES12804449T ES12804449T ES2811085T7 ES 2811085 T7 ES2811085 T7 ES 2811085T7 ES 12804449 T ES12804449 T ES 12804449T ES 12804449 T ES12804449 T ES 12804449T ES 2811085 T7 ES2811085 T7 ES 2811085T7
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- fibrinogen
- platelet lysate
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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- C12N5/0666—Mesenchymal stem cells from hair follicles
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- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/115—Platelets, megakaryocytes
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| PCT/US2012/044211 WO2013003356A1 (en) | 2011-06-27 | 2012-06-26 | Compositions, uses, and preparation of platelet lysates |
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| US9682104B2 (en) | 2012-01-26 | 2017-06-20 | Jadi Cell Llc | Lyophilized platelet lysates |
| EP2948210A4 (en) * | 2013-01-28 | 2016-10-19 | Regenerative Sciences Llc | DEVICE AND METHODS FOR LYING OR ACTIVATION OF BLOOD PLAQUETTES |
| US10905721B2 (en) | 2013-01-28 | 2021-02-02 | Regenexx, Llc. | Device and methods for platelet lysis or activation |
| WO2015031465A1 (en) * | 2013-08-27 | 2015-03-05 | Cook General Biotechnology Llc | Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same |
| HK1194912A2 (en) * | 2013-09-17 | 2014-10-24 | Bestop Group Holdings Ltd | Growth factor concentrate and the use thereof |
| WO2015148723A1 (en) * | 2014-03-25 | 2015-10-01 | Cook Biotech Incorporated | Extracellular matrix grafts loaded with exogenous factors |
| CA2974225C (en) * | 2015-01-21 | 2023-08-08 | Edvin TURKOF | Platelet concentrate for increase of cell regeneration and cell growth |
| EP3258945B1 (en) * | 2015-02-16 | 2020-10-07 | Nayacure Therapeutics Ltd. | Modified blood clots |
| KR102925966B1 (ko) | 2015-05-29 | 2026-02-10 | 자디 셀 엘엘씨 | 미립자 동결건조된 혈소판 용해물 조성물 |
| CN107304412A (zh) * | 2016-04-22 | 2017-10-31 | 南京医科大学第附属医院 | 视网膜色素上皮细胞的培养基及其应用 |
| EP3254684B1 (en) | 2016-06-08 | 2019-10-23 | Lysatpharma GmbH | Human platelet lysate or fraction enriched in human platelet-derived extracellular vesicles, for use in medicine |
| WO2018005751A1 (en) * | 2016-06-29 | 2018-01-04 | Arteriocyte, Inc. | Dressings comprising platelet lysate |
| CN110325226B (zh) * | 2016-12-22 | 2022-03-15 | 瑞金尼克斯有限责任公司 | 用于血小板裂解或激活的设备和方法 |
| IT201700026465A1 (it) * | 2017-03-09 | 2018-09-09 | Biorigen S R L | Supplementi per colture cellulari |
| IL271436B2 (en) * | 2017-06-16 | 2024-02-01 | Centre Hospitalier Regional Et Univ De Lille Chru | Process for preparing a pooled human platelet lysate, pooled human platelet lysate and its use for treating neurological disorders |
| ES2985827T3 (es) * | 2017-12-22 | 2024-11-07 | Chiesi Farm Spa | Células estromales mesenquimales y procedimientos de obtención de células estromales mesenquimales a partir del cordón umbilical |
| FR3077823B1 (fr) | 2018-02-15 | 2022-01-14 | Maco Pharma Sa | Procede de preparation d'un lysat plaquettaire irradie |
| FR3077824B1 (fr) | 2018-02-15 | 2022-01-14 | Maco Pharma Sa | Procede de preparation d'un lysat plaquettaire irradie |
| CN108823156A (zh) * | 2018-07-04 | 2018-11-16 | 陕西神州生物技术有限公司 | 用于修复的临床级人脐带间充质干细胞复合因子及冻干粉的制备方法 |
| US12171784B2 (en) * | 2018-08-07 | 2024-12-24 | iFiX Medical Pty Ltd | Platelet lysate compositions and uses thereof |
| EP3880217B1 (en) * | 2018-11-14 | 2024-01-03 | Onderzoeks en Ontwikkelingsfonds Rode Kruis-Vlaanderen | Methods for preparing platelet releasate |
| WO2020112963A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets as delivery agents |
| CA3121200A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets as delivery agents |
| EP3920944A4 (en) * | 2019-02-07 | 2023-03-29 | Biobridge Global | METHODS AND COMPOSITIONS RELATED TO PLATELET RELEASTAT AND PLATELET-RICH FIBRIN |
| IL322149A (en) | 2019-05-03 | 2025-09-01 | Cellphire Inc | Materials and methods for manufacturing blood products |
| AU2020277774A1 (en) * | 2019-05-22 | 2021-12-09 | Thankstem S.R.L. | Method for expanding adult stem cells from whole blood |
| CN114450066A (zh) | 2019-08-16 | 2022-05-06 | 塞尔菲乐有限公司 | 作为抗血小板剂逆转剂的血栓小体 |
| WO2021035205A1 (en) * | 2019-08-22 | 2021-02-25 | Awidi Abdalla S | Method of preparing a de-fibrinated platelet lysate, and uses of said method |
| CA3170196A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Anti-fibrinolytic loaded platelets |
| CN111303270B (zh) * | 2020-02-18 | 2022-04-01 | 浙江中医药大学 | 一种利用套装制备血小板生长因子浓集物的方法 |
| EP3881858A1 (en) | 2020-03-20 | 2021-09-22 | Rok Pangersic | Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect |
| CN111569139A (zh) * | 2020-05-26 | 2020-08-25 | 上海市第六人民医院 | 一种负载血小板裂解液的自支撑自组装多层膜及其应用 |
| EP4190892A4 (en) * | 2020-07-31 | 2024-10-30 | Rainbow Inc. | Platelet lysate derived from autologous platelets |
| TW202245814A (zh) | 2021-02-17 | 2022-12-01 | 美商賽菲爾公司 | 用於治療抗血小板誘導的凝血病之凍乾血小板衍生物組成物 |
| CN113667636B (zh) * | 2021-07-13 | 2024-09-24 | 安徽农业大学 | 猪血小板裂解液及其制备方法 |
| CN114058576A (zh) * | 2021-11-22 | 2022-02-18 | 新乡医学院 | 一种血小板裂解液及其制备方法和应用 |
| CN114317430A (zh) * | 2021-12-28 | 2022-04-12 | 河北银丰鼎诚生物技术有限公司 | 一种适用于脐血来源免疫细胞扩增的培养液 |
| WO2023190736A1 (ja) * | 2022-03-29 | 2023-10-05 | 学校法人日本大学 | ヒト脱分化脂肪細胞の製造方法及びヒト成熟脂肪細胞からヒト脱分化脂肪細胞を製造するための培地 |
| EP4276173A1 (en) * | 2022-05-10 | 2023-11-15 | Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. | Stable human platelet lysate composition, methods and uses thereof |
| CN120225662A (zh) * | 2022-12-06 | 2025-06-27 | 苏州血霁生物科技有限公司 | 一种分化血小板的方法、培养基及应用 |
| TWI909123B (zh) | 2022-12-30 | 2025-12-21 | 思必瑞特生技股份有限公司 | 含血小板之組合物及其製備方法 |
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| CN100540237C (zh) * | 2004-08-02 | 2009-09-16 | 本田技研工业株式会社 | 腿式移动机器人的控制方法 |
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| WO2008034803A1 (en) * | 2006-09-18 | 2008-03-27 | Medizinische Universität Graz | Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics |
| US7951593B2 (en) * | 2007-03-20 | 2011-05-31 | Universite Rene Descartes-Paris V | Culture medium for gingival fibroblasts |
| WO2009085969A2 (en) | 2007-12-19 | 2009-07-09 | Regenerative Sciences, Llc | Compositions and methods to promote implantation and engrafment of stem cells |
| EP2077118A1 (en) | 2008-01-07 | 2009-07-08 | Gwo Rei Biomedical Technology Corp. | Clottable concentrate of platelet growth factors and preparation method thereof |
| CN102026546A (zh) | 2008-03-14 | 2011-04-20 | 再生科学有限责任公司 | 软骨修复的合成物和方法 |
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| EP2334785B2 (en) * | 2008-09-16 | 2019-08-14 | Mayo Foundation For Medical Education And Research | Compositions containing platelet contents |
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| DK2373321T3 (en) | 2008-12-05 | 2016-06-13 | Biomed Device S R L | Biovedhæftende platelet lysate and compositions thereof for the treatment of mucostitis |
| ITPI20090066A1 (it) | 2009-05-26 | 2010-11-27 | Consiglio Nazionale Ricerche | Metodo per produrre un dispositivo applicabile a tessuti biologici, in particolare un patch per trattare tessuti danneggiati, e dispositivo ottenuto con tale metodo |
| ES2402144T3 (es) | 2010-05-25 | 2013-04-29 | Gwowei Technology Co., Ltd. | Lisado plaquetario inactivado que contiene factores de crecimiento empobrecido en PDGF y VEGF y su procedimiento de preparación |
| DK3067431T3 (da) | 2010-09-15 | 2019-10-14 | Debiopharm Int Sa | Indretning omfattende blodkomponenter til at adskille målmolekyler eller partikler fra prøver |
| IL210162A0 (en) * | 2010-12-21 | 2011-03-31 | Omrix Biopharmaceuticals | Viral inactivated platelet extract, use and preparation thereof |
| EP2540819A1 (en) | 2011-06-27 | 2013-01-02 | Rheinisch-Westfälische Technische Hochschule Aachen (RWTH) | Method for cultivating cells in platelet-lysate-containing medium |
| EP2591812A1 (en) | 2011-11-14 | 2013-05-15 | University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) | A dextran-based tissuelette containing platelet-rich plasma lysate for cartilage repair |
| TR201908716T4 (tr) | 2011-11-23 | 2019-07-22 | Cell Therapy Ltd | Platelet lizat jeli. |
| US9682104B2 (en) | 2012-01-26 | 2017-06-20 | Jadi Cell Llc | Lyophilized platelet lysates |
| WO2013116791A1 (en) | 2012-02-02 | 2013-08-08 | Mosaic Biosciences, Inc. | Biomaterials for delivery of blood extracts and methods of using same |
| EP2733200A1 (en) | 2012-11-15 | 2014-05-21 | Biorigen International SA | Cell culture supplements |
| AU2013365623B2 (en) | 2012-12-20 | 2017-08-24 | Omrix Biopharmaceuticals Ltd. | Viral inactivated biological mixture |
| WO2015031465A1 (en) * | 2013-08-27 | 2015-03-05 | Cook General Biotechnology Llc | Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same |
| TW201914595A (zh) * | 2017-09-27 | 2019-04-16 | 法國里爾中央醫學中心 | 製備血小板裂解物組分的方法、血小板裂解物組分及其用於治療中樞神經系統疾病的用途 |
| JP2021506931A (ja) * | 2017-12-20 | 2021-02-22 | クック リージェンテック エルエルシーＣｏｏｋ Ｒｅｇｅｎｔｅｃ Ｌｌｃ | 病原体減少血小板組成物および関連方法 |
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| AU2012275562A1 (en) | 2014-01-23 |
| US9688959B2 (en) | 2017-06-27 |
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| US20140127314A1 (en) | 2014-05-08 |
| US20170304365A1 (en) | 2017-10-26 |
| CN108671224B (zh) | 2022-12-13 |
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