JP6159504B2 - 医薬品成分を被覆するための無溶剤混合方法 - Google Patents

医薬品成分を被覆するための無溶剤混合方法 Download PDF

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JP6159504B2
JP6159504B2 JP2015536852A JP2015536852A JP6159504B2 JP 6159504 B2 JP6159504 B2 JP 6159504B2 JP 2015536852 A JP2015536852 A JP 2015536852A JP 2015536852 A JP2015536852 A JP 2015536852A JP 6159504 B2 JP6159504 B2 JP 6159504B2
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particles
water
coating
coated
particle size
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JP2015533162A (ja
JP2015533162A5 (enExample
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デーヴ、ラジェッシュ、エヌ．
トゥー、ダニエル
カペーチェ、マックス
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ニュー ジャージー インスティチュート オブ テクノロジー
ニュー ジャージー インスティチュート オブ テクノロジー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015536852A 2012-10-15 2013-10-09 医薬品成分を被覆するための無溶剤混合方法 Active JP6159504B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/651,977 US9107851B2 (en) 2012-10-15 2012-10-15 Solventless mixing process for coating pharmaceutical ingredients
US13/651,977 2012-10-15
PCT/US2013/064058 WO2014062444A1 (en) 2012-10-15 2013-10-09 Solventless mixing process for coating pharmaceutical ingredients

Publications (3)

Publication Number Publication Date
JP2015533162A JP2015533162A (ja) 2015-11-19
JP2015533162A5 JP2015533162A5 (enExample) 2016-11-17
JP6159504B2 true JP6159504B2 (ja) 2017-07-05

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JP2015536852A Active JP6159504B2 (ja) 2012-10-15 2013-10-09 医薬品成分を被覆するための無溶剤混合方法

Country Status (16)

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US (1) US9107851B2 (enExample)
EP (1) EP2906205B1 (enExample)
JP (1) JP6159504B2 (enExample)
CN (1) CN104853751B (enExample)
AR (1) AR093013A1 (enExample)
BR (1) BR112015008285B1 (enExample)
CY (1) CY1121241T1 (enExample)
DK (1) DK2906205T3 (enExample)
ES (1) ES2688889T3 (enExample)
HR (1) HRP20181463T1 (enExample)
HU (1) HUE039772T2 (enExample)
PL (1) PL2906205T3 (enExample)
PT (1) PT2906205T (enExample)
RS (1) RS57918B1 (enExample)
SI (1) SI2906205T1 (enExample)
WO (1) WO2014062444A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016011412A1 (en) 2014-07-17 2016-01-21 Ada Technologies, Inc. Extreme long life, high energy density batteries and method of making and using the same
CN104587472B (zh) * 2014-12-31 2017-12-15 广东国方医药科技有限公司 一种含纳米SiO2的包衣剂及其制备方法
US10217571B2 (en) 2015-05-21 2019-02-26 Ada Technologies, Inc. High energy density hybrid pseudocapacitors and method of making and using the same
US12401042B2 (en) 2015-06-01 2025-08-26 Forge Nano Inc. Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings
US12027661B2 (en) 2015-06-01 2024-07-02 Forge Nano Inc. Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings
US11996564B2 (en) 2015-06-01 2024-05-28 Forge Nano Inc. Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings
US10692659B2 (en) 2015-07-31 2020-06-23 Ada Technologies, Inc. High energy and power electrochemical device and method of making and using same
JP7069538B2 (ja) * 2016-12-05 2022-05-18 マルボシ酢株式会社 食酢含有飲料組成物
US11024846B2 (en) 2017-03-23 2021-06-01 Ada Technologies, Inc. High energy/power density, long cycle life, safe lithium-ion battery capable of long-term deep discharge/storage near zero volt and method of making and using the same
WO2019009335A1 (ja) * 2017-07-04 2019-01-10 村上　正裕 微粒子の製造方法及び微粒子
BR112021016485A2 (pt) * 2019-02-22 2021-10-13 Catalent U.K. Swindon Zydis Limited Minimização de aglomeração de material de revestimento de partícula de fármaco durante armazenamento para estabilizar tempos de desintegração de produtos farmacêuticos
AR118418A1 (es) 2019-02-22 2021-10-06 Catalent Uk Swindon Zydis Ltd Conservación de partículas ifa revestidas funcionalmente producidas mediante procesos de mezcla sin solvente en suspensión acuosa
CN113490486B (zh) 2019-02-22 2025-10-17 康特伦英国斯温顿捷迪斯有限公司 最小化团聚、曝气和保持包含布洛芬的药物组合物的包衣
CA3129383A1 (en) 2019-02-22 2020-08-27 Catalent U.K. Swindon Zydis Limited Minimizing aeration of suspensions during in-line mixing
US20210009767A1 (en) * 2019-07-11 2021-01-14 International Flavors & Fragrances Inc. Solventless particle coating via acoustic mixing
US12285731B2 (en) 2019-09-12 2025-04-29 United States Of America, As Represented By The Secretary Of The Army Acoustic mixing system for creating propellant mixture
MX2023001004A (es) * 2020-07-31 2023-03-01 Catalent Uk Swindon Zydis Ltd Composiciones farmaceuticas que comprenden un ingrediente farmaceutico activo (api) recubierto.
CN120053389A (zh) * 2025-02-25 2025-05-30 江苏亚邦爱普森药业有限公司 一种含有替米沙坦药物的片剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628945A (en) 1992-08-03 1997-05-13 Riman; Richard E. Multicomponent powder mixing process and compositions produced thereby
WO1994015374A1 (fr) * 1992-12-25 1994-07-07 Tdk Corporation Element secondaire au lithium
US5769917A (en) * 1996-12-09 1998-06-23 Belko; William C. Process for producing low shrink ceramic bodies
US6740341B1 (en) 1998-11-25 2004-05-25 Cima Labs Inc. Taste masking rapid release coating system
DE10062176A1 (de) * 2000-12-14 2002-07-04 Wacker Polymer Systems Gmbh Polyvinylacetal-gepfropfte Polymerisate
US8163114B2 (en) 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
DE102004059792A1 (de) * 2004-12-10 2006-06-14 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
US20060210694A1 (en) * 2005-03-18 2006-09-21 Chappell Rulon A Anti-caking agents and methods
US7862848B2 (en) 2005-08-03 2011-01-04 The University Of Western Ontario Direct coating solid dosage forms using powdered materials
WO2011155451A1 (ja) 2010-06-08 2011-12-15 学校法人神戸学院 コーティング粒子及びコーティング粒子の製造方法
GB201205632D0 (en) 2012-03-30 2012-05-16 Vectura Ltd Method and apparatus
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them

Also Published As

Publication number Publication date
PL2906205T3 (pl) 2019-03-29
CN104853751B (zh) 2018-06-22
CY1121241T1 (el) 2020-05-29
BR112015008285B1 (pt) 2022-11-16
JP2015533162A (ja) 2015-11-19
EP2906205B1 (en) 2018-06-13
CN104853751A (zh) 2015-08-19
US20140106059A1 (en) 2014-04-17
HRP20181463T1 (hr) 2018-12-14
US9107851B2 (en) 2015-08-18
BR112015008285A2 (pt) 2017-07-04
DK2906205T3 (en) 2018-09-24
WO2014062444A1 (en) 2014-04-24
HUE039772T2 (hu) 2019-02-28
RS57918B1 (sr) 2019-01-31
AR093013A1 (es) 2015-05-13
EP2906205A1 (en) 2015-08-19
SI2906205T1 (sl) 2018-12-31
PT2906205T (pt) 2018-11-07
ES2688889T3 (es) 2018-11-07

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