JP6145667B2 - アロディニア、痛覚過敏、自発痛、及び幻痛の治療 - Google Patents

アロディニア、痛覚過敏、自発痛、及び幻痛の治療 Download PDF

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JP6145667B2
JP6145667B2 JP2014528860A JP2014528860A JP6145667B2 JP 6145667 B2 JP6145667 B2 JP 6145667B2 JP 2014528860 A JP2014528860 A JP 2014528860A JP 2014528860 A JP2014528860 A JP 2014528860A JP 6145667 B2 JP6145667 B2 JP 6145667B2
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seq
cometin
allodynia
hyperalgesia
sequence
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Japanese (ja)
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JP2014529408A5 (enExample
JP2014529408A (ja
Inventor
ヨルゲンセン,イェスパ・ローラン
ヴァルベアウ,ラース・ウルレク
ヨハンセン,テイト・イ.
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ホーバ セラピューティクス アンパルトセルスカブ
ホーバ セラピューティクス アンパルトセルスカブ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
JP2014528860A 2011-09-05 2012-09-05 アロディニア、痛覚過敏、自発痛、及び幻痛の治療 Active JP6145667B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161531024P 2011-09-05 2011-09-05
US61/531,024 2011-09-05
PCT/DK2012/050330 WO2013034157A1 (en) 2011-09-05 2012-09-05 Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain

Publications (3)

Publication Number Publication Date
JP2014529408A JP2014529408A (ja) 2014-11-13
JP2014529408A5 JP2014529408A5 (enExample) 2015-11-05
JP6145667B2 true JP6145667B2 (ja) 2017-06-14

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JP2014528860A Active JP6145667B2 (ja) 2011-09-05 2012-09-05 アロディニア、痛覚過敏、自発痛、及び幻痛の治療

Country Status (8)

Country Link
US (2) US9474786B2 (enExample)
EP (1) EP2753347B1 (enExample)
JP (1) JP6145667B2 (enExample)
KR (1) KR102075881B1 (enExample)
CN (2) CN107596346A (enExample)
AU (1) AU2012306810B2 (enExample)
CA (1) CA2846511C (enExample)
WO (1) WO2013034157A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010009732A1 (en) 2008-07-24 2010-01-28 Nsgene A/S Therapeutic use of a growth factor, metrnl
JP7140353B2 (ja) * 2017-12-29 2022-09-22 ヘリックスミス カンパニー, リミテッド ハイブリッドhgf遺伝子が導入されたaav(アデノ-関連ウイルス)ベクター
CN110004223A (zh) * 2019-05-09 2019-07-12 苏州大学附属第一医院 一种用于预测早发型子痫前期发病的检测试剂盒
JP2024518433A (ja) * 2021-05-06 2024-05-01 ホバ セラピューティクス エーピーエス 化学療法誘発性神経障害性疼痛の予防及び治療
KR20240118796A (ko) * 2021-12-10 2024-08-05 호바 세라퓨틱스 에이피에스 침해수용성 통증의 치료

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DE3681787D1 (de) 1985-07-05 1991-11-07 Whitehead Biomedical Inst Expression von fremdem genetischem material in epithelzellen.
HK1008049A1 (en) 1987-09-11 1999-04-30 Whitehead Institute For Biomedical Research Transduced fibroblasts and use therefor
US4892538A (en) 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells
US5156844A (en) 1987-11-17 1992-10-20 Brown University Research Foundation Neurological therapy system
US5283187A (en) 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
US5106627A (en) 1987-11-17 1992-04-21 Brown University Research Foundation Neurological therapy devices
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SG47470A1 (en) 1991-04-25 1998-04-17 Univ Brown Res Found Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products
PT639225E (pt) 1992-04-30 2003-03-31 Innogenetics Nv Polipeptidos e peptidos novos acidos nucleicos que codificam para aqueles e sua utilizacao na area da terapia tumoral inflamacao ou imunologia
ES2178654T3 (es) 1993-08-12 2003-01-01 Neurotech Sa Capsulas biocompatibles inmonoaisladoras que contienen celulas geneticamente alteradas para el suministro de moleculas biologicamente activas.
US5550050A (en) 1994-04-15 1996-08-27 Cytotherapeutics, Inc. Method for implanting encapsulated cells in a host
US5677158A (en) 1995-06-07 1997-10-14 Research Foundation Of State University Of New York In vitro packaging of adeno-associated virus DNA
US5904144A (en) 1996-03-22 1999-05-18 Cytotherapeutics, Inc. Method for treating ophthalmic diseases
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US6683058B1 (en) 1998-04-15 2004-01-27 Regents Of The University Of California Methods for therapy of neurodegenerative disease of the brain
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EP1225224A4 (en) 1999-10-01 2004-03-24 Kyowa Hakko Kogyo Kk DNA THE SHEAR RESPONSE
AU1395801A (en) 1999-11-30 2001-06-12 Innogenetics N.V. New uses of suppressive macrophage activation factors
CA2395676A1 (en) 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001055448A1 (en) 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
AU2001234944A1 (en) 2000-02-03 2001-08-14 Hyseq, Inc. Novel nucleic acids and polypeptides
ES2374971T3 (es) 2001-03-28 2012-02-23 Biogen Idec Ma Inc. Uso de polipéptidos de neublastina para el tratamiento del dolor neuropático.
US20050208062A1 (en) 2001-12-21 2005-09-22 Yongming Sun Compositions and methods relating to hepatic specific genes and proteins
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JP6149226B2 (ja) 2010-10-01 2017-06-21 ホーバ セラピューティクス アンパルトセルスカブ アロディニア、痛覚過敏、自発痛及び幻肢痛の処置

Also Published As

Publication number Publication date
KR102075881B1 (ko) 2020-02-11
US9861682B2 (en) 2018-01-09
US20150231208A1 (en) 2015-08-20
AU2012306810A1 (en) 2014-03-13
KR20140068148A (ko) 2014-06-05
US20170143794A1 (en) 2017-05-25
EP2753347A1 (en) 2014-07-16
HK1199395A1 (en) 2015-07-03
AU2012306810B2 (en) 2017-09-28
US9474786B2 (en) 2016-10-25
CN104105501B (zh) 2017-10-20
CA2846511C (en) 2021-07-13
WO2013034157A1 (en) 2013-03-14
CA2846511A1 (en) 2013-03-14
EP2753347B1 (en) 2016-08-03
JP2014529408A (ja) 2014-11-13
CN107596346A (zh) 2018-01-19
CN104105501A (zh) 2014-10-15

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