AU2012306810B2 - Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain - Google Patents

Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain Download PDF

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Publication number
AU2012306810B2
AU2012306810B2 AU2012306810A AU2012306810A AU2012306810B2 AU 2012306810 B2 AU2012306810 B2 AU 2012306810B2 AU 2012306810 A AU2012306810 A AU 2012306810A AU 2012306810 A AU2012306810 A AU 2012306810A AU 2012306810 B2 AU2012306810 B2 AU 2012306810B2
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AU
Australia
Prior art keywords
seq
cometin
polypeptide
allodynia
hyperalgesia
Prior art date
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Application number
AU2012306810A
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English (en)
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AU2012306810A1 (en
Inventor
Teit E. Johansen
Jesper Roland Jorgensen
Lars Ulrik Wahlberg
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Hoba Therapeutics Aps
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Hoba Therapeutics Aps
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Publication of AU2012306810A1 publication Critical patent/AU2012306810A1/en
Assigned to HOBA THERAPEUTICS APS reassignment HOBA THERAPEUTICS APS Request for Assignment Assignors: NSGENE A/S
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AU2012306810A 2011-09-05 2012-09-05 Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain Active AU2012306810B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161531024P 2011-09-05 2011-09-05
US61/531,024 2011-09-05
PCT/DK2012/050330 WO2013034157A1 (en) 2011-09-05 2012-09-05 Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain

Publications (2)

Publication Number Publication Date
AU2012306810A1 AU2012306810A1 (en) 2014-03-13
AU2012306810B2 true AU2012306810B2 (en) 2017-09-28

Family

ID=46940179

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012306810A Active AU2012306810B2 (en) 2011-09-05 2012-09-05 Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain

Country Status (8)

Country Link
US (2) US9474786B2 (enExample)
EP (1) EP2753347B1 (enExample)
JP (1) JP6145667B2 (enExample)
KR (1) KR102075881B1 (enExample)
CN (2) CN107596346A (enExample)
AU (1) AU2012306810B2 (enExample)
CA (1) CA2846511C (enExample)
WO (1) WO2013034157A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010009732A1 (en) 2008-07-24 2010-01-28 Nsgene A/S Therapeutic use of a growth factor, metrnl
JP7140353B2 (ja) * 2017-12-29 2022-09-22 ヘリックスミス カンパニー, リミテッド ハイブリッドhgf遺伝子が導入されたaav(アデノ-関連ウイルス)ベクター
CN110004223A (zh) * 2019-05-09 2019-07-12 苏州大学附属第一医院 一种用于预测早发型子痫前期发病的检测试剂盒
JP2024518433A (ja) * 2021-05-06 2024-05-01 ホバ セラピューティクス エーピーエス 化学療法誘発性神経障害性疼痛の予防及び治療
KR20240118796A (ko) * 2021-12-10 2024-08-05 호바 세라퓨틱스 에이피에스 침해수용성 통증의 치료

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010009732A1 (en) * 2008-07-24 2010-01-28 Nsgene A/S Therapeutic use of a growth factor, metrnl

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HK1008049A1 (en) 1987-09-11 1999-04-30 Whitehead Institute For Biomedical Research Transduced fibroblasts and use therefor
US4892538A (en) 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells
US5156844A (en) 1987-11-17 1992-10-20 Brown University Research Foundation Neurological therapy system
US5283187A (en) 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
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PT639225E (pt) 1992-04-30 2003-03-31 Innogenetics Nv Polipeptidos e peptidos novos acidos nucleicos que codificam para aqueles e sua utilizacao na area da terapia tumoral inflamacao ou imunologia
ES2178654T3 (es) 1993-08-12 2003-01-01 Neurotech Sa Capsulas biocompatibles inmonoaisladoras que contienen celulas geneticamente alteradas para el suministro de moleculas biologicamente activas.
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ES2374971T3 (es) 2001-03-28 2012-02-23 Biogen Idec Ma Inc. Uso de polipéptidos de neublastina para el tratamiento del dolor neuropático.
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Patent Citations (1)

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WO2010009732A1 (en) * 2008-07-24 2010-01-28 Nsgene A/S Therapeutic use of a growth factor, metrnl

Also Published As

Publication number Publication date
KR102075881B1 (ko) 2020-02-11
US9861682B2 (en) 2018-01-09
US20150231208A1 (en) 2015-08-20
AU2012306810A1 (en) 2014-03-13
JP6145667B2 (ja) 2017-06-14
KR20140068148A (ko) 2014-06-05
US20170143794A1 (en) 2017-05-25
EP2753347A1 (en) 2014-07-16
HK1199395A1 (en) 2015-07-03
US9474786B2 (en) 2016-10-25
CN104105501B (zh) 2017-10-20
CA2846511C (en) 2021-07-13
WO2013034157A1 (en) 2013-03-14
CA2846511A1 (en) 2013-03-14
EP2753347B1 (en) 2016-08-03
JP2014529408A (ja) 2014-11-13
CN107596346A (zh) 2018-01-19
CN104105501A (zh) 2014-10-15

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Owner name: HOBA THERAPEUTICS APS

Free format text: FORMER APPLICANT(S): NSGENE A/S

FGA Letters patent sealed or granted (standard patent)