JP6140187B2 - 心筋灌流イマジニング用造影剤 - Google Patents

心筋灌流イマジニング用造影剤 Download PDF

Info

Publication number
JP6140187B2
JP6140187B2 JP2014548735A JP2014548735A JP6140187B2 JP 6140187 B2 JP6140187 B2 JP 6140187B2 JP 2014548735 A JP2014548735 A JP 2014548735A JP 2014548735 A JP2014548735 A JP 2014548735A JP 6140187 B2 JP6140187 B2 JP 6140187B2
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
imaging
isotope
imaging agent
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2014548735A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015500873A (ja
JP2015500873A5 (enExample
Inventor
ヨハンソン,マルティン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Respiratorius AB
Original Assignee
Respiratorius AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respiratorius AB filed Critical Respiratorius AB
Publication of JP2015500873A publication Critical patent/JP2015500873A/ja
Publication of JP2015500873A5 publication Critical patent/JP2015500873A5/ja
Application granted granted Critical
Publication of JP6140187B2 publication Critical patent/JP6140187B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2014548735A 2011-12-22 2012-12-18 心筋灌流イマジニング用造影剤 Expired - Fee Related JP6140187B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161579113P 2011-12-22 2011-12-22
SE1151249-8 2011-12-22
SE1151249 2011-12-22
US61/579,113 2011-12-22
PCT/SE2012/051421 WO2013095273A1 (en) 2011-12-22 2012-12-18 Contrast agent for imagining myocardial perfusion

Publications (3)

Publication Number Publication Date
JP2015500873A JP2015500873A (ja) 2015-01-08
JP2015500873A5 JP2015500873A5 (enExample) 2016-02-12
JP6140187B2 true JP6140187B2 (ja) 2017-05-31

Family

ID=48668967

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014548735A Expired - Fee Related JP6140187B2 (ja) 2011-12-22 2012-12-18 心筋灌流イマジニング用造影剤

Country Status (15)

Country Link
US (2) US9295738B2 (enExample)
EP (1) EP2793952B1 (enExample)
JP (1) JP6140187B2 (enExample)
KR (1) KR101931792B1 (enExample)
CN (1) CN104114191A (enExample)
AU (1) AU2012354223B2 (enExample)
BR (1) BR112014015124A2 (enExample)
CA (1) CA2859773C (enExample)
ES (1) ES2687234T3 (enExample)
IL (1) IL233219A (enExample)
MX (1) MX356258B (enExample)
RU (1) RU2629840C2 (enExample)
SG (1) SG11201403429YA (enExample)
WO (1) WO2013095273A1 (enExample)
ZA (1) ZA201405199B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9955876B2 (en) * 2016-09-08 2018-05-01 Raul Chirife Device and method for assessment of left ventricular ejection fraction and other parameters of cardiac performance
CN107233585B (zh) * 2017-06-09 2021-01-22 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
US7824659B2 (en) 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
US8415333B2 (en) * 2009-02-24 2013-04-09 Respiratorious Ab Bronchodilating diazaheteroaryls

Also Published As

Publication number Publication date
CN104114191A (zh) 2014-10-22
MX356258B (es) 2018-05-16
HK1201459A1 (en) 2015-09-04
US20160101195A1 (en) 2016-04-14
JP2015500873A (ja) 2015-01-08
RU2014125849A (ru) 2016-02-10
US9687565B2 (en) 2017-06-27
IL233219A (en) 2016-08-31
CA2859773A1 (en) 2013-06-27
WO2013095273A1 (en) 2013-06-27
CA2859773C (en) 2020-09-01
KR101931792B1 (ko) 2019-03-13
ES2687234T3 (es) 2018-10-24
AU2012354223B2 (en) 2017-03-16
EP2793952B1 (en) 2018-06-13
US20140341808A1 (en) 2014-11-20
US9295738B2 (en) 2016-03-29
EP2793952A1 (en) 2014-10-29
IL233219A0 (en) 2014-08-31
RU2629840C2 (ru) 2017-09-04
EP2793952A4 (en) 2015-09-09
BR112014015124A2 (pt) 2017-06-13
SG11201403429YA (en) 2014-07-30
KR20140107411A (ko) 2014-09-04
AU2012354223A1 (en) 2014-07-03
MX2014007491A (es) 2015-02-17
ZA201405199B (en) 2015-12-23

Similar Documents

Publication Publication Date Title
CN106977429B (zh) 用于合成和使用造影剂的组合物、方法和系统
JP6786610B2 (ja) エリブリンの合成における中間体および関連する合成方法
JP6987840B2 (ja) Ido1酵素イメージングのための放射性リガンド
RU2641285C2 (ru) Соединения хинина, способ их получения и их медицинское применение
US20240042066A1 (en) Fibroblast activation protein inhibitor
JP6140187B2 (ja) 心筋灌流イマジニング用造影剤
HK1201459B (en) Contrast agent for imagining myocardial perfusion
WO2014184682A1 (en) Radiolabeled gnrh antagonists as pet imaging agents
CN113387896B (zh) 一种4-(2-氯芳基)喹唑啉-2-酰胺衍生物及其应用
JP6488045B2 (ja) アセチルコリン小胞トランスポーターの検出に適した化合物
JP6496101B2 (ja) アセチルコリン小胞トランスポーターの検出に適した化合物
HK1241356A1 (en) Compositions, methods and systems for the synthesis and use of imaging agents
CN108066776A (zh) 快速成像的坏死心肌显像剂及其制备方法和应用
HK1182933A (en) Compositions, methods and systems for the synthesis and use of imaging agents

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151217

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20151217

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160913

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20161125

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20170213

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170313

TRDD Decision of grant or rejection written
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20170314

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20170404

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170428

R150 Certificate of patent or registration of utility model

Ref document number: 6140187

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees