CN104114191A - 心肌灌注显像造影剂 - Google Patents

心肌灌注显像造影剂 Download PDF

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Publication number
CN104114191A
CN104114191A CN201280069796.5A CN201280069796A CN104114191A CN 104114191 A CN104114191 A CN 104114191A CN 201280069796 A CN201280069796 A CN 201280069796A CN 104114191 A CN104114191 A CN 104114191A
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CN
China
Prior art keywords
developer
compound
patient
acid
isotope
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280069796.5A
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English (en)
Chinese (zh)
Inventor
马丁·约翰森
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Respiratorius AB
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Respiratorius AB
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Publication date
Application filed by Respiratorius AB filed Critical Respiratorius AB
Publication of CN104114191A publication Critical patent/CN104114191A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN201280069796.5A 2011-12-22 2012-12-18 心肌灌注显像造影剂 Pending CN104114191A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161579113P 2011-12-22 2011-12-22
SE1151249-8 2011-12-22
SE1151249 2011-12-22
US61/579,113 2011-12-22
PCT/SE2012/051421 WO2013095273A1 (en) 2011-12-22 2012-12-18 Contrast agent for imagining myocardial perfusion

Publications (1)

Publication Number Publication Date
CN104114191A true CN104114191A (zh) 2014-10-22

Family

ID=48668967

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280069796.5A Pending CN104114191A (zh) 2011-12-22 2012-12-18 心肌灌注显像造影剂

Country Status (15)

Country Link
US (2) US9295738B2 (enExample)
EP (1) EP2793952B1 (enExample)
JP (1) JP6140187B2 (enExample)
KR (1) KR101931792B1 (enExample)
CN (1) CN104114191A (enExample)
AU (1) AU2012354223B2 (enExample)
BR (1) BR112014015124A2 (enExample)
CA (1) CA2859773C (enExample)
ES (1) ES2687234T3 (enExample)
IL (1) IL233219A (enExample)
MX (1) MX356258B (enExample)
RU (1) RU2629840C2 (enExample)
SG (1) SG11201403429YA (enExample)
WO (1) WO2013095273A1 (enExample)
ZA (1) ZA201405199B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107233585A (zh) * 2017-06-09 2017-10-10 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9955876B2 (en) * 2016-09-08 2018-05-01 Raul Chirife Device and method for assessment of left ventricular ejection fraction and other parameters of cardiac performance

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007021858A2 (en) * 2005-08-10 2007-02-22 Bristol-Myers Squibb Pharma Company Methods of making radiolabeled tracers and precursors thereof
CN1925878A (zh) * 2004-02-13 2007-03-07 布里斯托尔-迈尔斯·斯奎布制药公司 供心肌灌注成像所用的对比剂
WO2010097410A1 (en) * 2009-02-24 2010-09-02 Respiratorius Ab Novel bronchodilating diazaheteroaryls

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1925878A (zh) * 2004-02-13 2007-03-07 布里斯托尔-迈尔斯·斯奎布制药公司 供心肌灌注成像所用的对比剂
WO2007021858A2 (en) * 2005-08-10 2007-02-22 Bristol-Myers Squibb Pharma Company Methods of making radiolabeled tracers and precursors thereof
WO2010097410A1 (en) * 2009-02-24 2010-09-02 Respiratorius Ab Novel bronchodilating diazaheteroaryls

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
魏敏吉 等主编: "同位素示踪技术在创新药物药代动力学研究中的应用", 《创新药物药代动力学研究与评价》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107233585A (zh) * 2017-06-09 2017-10-10 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途
CN107233585B (zh) * 2017-06-09 2021-01-22 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途

Also Published As

Publication number Publication date
MX356258B (es) 2018-05-16
HK1201459A1 (en) 2015-09-04
US20160101195A1 (en) 2016-04-14
JP2015500873A (ja) 2015-01-08
RU2014125849A (ru) 2016-02-10
US9687565B2 (en) 2017-06-27
IL233219A (en) 2016-08-31
CA2859773A1 (en) 2013-06-27
WO2013095273A1 (en) 2013-06-27
CA2859773C (en) 2020-09-01
KR101931792B1 (ko) 2019-03-13
ES2687234T3 (es) 2018-10-24
AU2012354223B2 (en) 2017-03-16
EP2793952B1 (en) 2018-06-13
US20140341808A1 (en) 2014-11-20
JP6140187B2 (ja) 2017-05-31
US9295738B2 (en) 2016-03-29
EP2793952A1 (en) 2014-10-29
IL233219A0 (en) 2014-08-31
RU2629840C2 (ru) 2017-09-04
EP2793952A4 (en) 2015-09-09
BR112014015124A2 (pt) 2017-06-13
SG11201403429YA (en) 2014-07-30
KR20140107411A (ko) 2014-09-04
AU2012354223A1 (en) 2014-07-03
MX2014007491A (es) 2015-02-17
ZA201405199B (en) 2015-12-23

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Application publication date: 20141022

RJ01 Rejection of invention patent application after publication