CA2859773C - Contrast agent for imagining myocardial perfusion - Google Patents

Contrast agent for imagining myocardial perfusion Download PDF

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Publication number
CA2859773C
CA2859773C CA2859773A CA2859773A CA2859773C CA 2859773 C CA2859773 C CA 2859773C CA 2859773 A CA2859773 A CA 2859773A CA 2859773 A CA2859773 A CA 2859773A CA 2859773 C CA2859773 C CA 2859773C
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CA
Canada
Prior art keywords
imaging
imaging agent
use according
patient
heart
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2859773A
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English (en)
French (fr)
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CA2859773A1 (en
Inventor
Martin Johansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Respiratorius AB
Original Assignee
Respiratorius AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respiratorius AB filed Critical Respiratorius AB
Publication of CA2859773A1 publication Critical patent/CA2859773A1/en
Application granted granted Critical
Publication of CA2859773C publication Critical patent/CA2859773C/en
Active legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA2859773A 2011-12-22 2012-12-18 Contrast agent for imagining myocardial perfusion Active CA2859773C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161579113P 2011-12-22 2011-12-22
SE1151249-8 2011-12-22
SE1151249 2011-12-22
US61/579,113 2011-12-22
PCT/SE2012/051421 WO2013095273A1 (en) 2011-12-22 2012-12-18 Contrast agent for imagining myocardial perfusion

Publications (2)

Publication Number Publication Date
CA2859773A1 CA2859773A1 (en) 2013-06-27
CA2859773C true CA2859773C (en) 2020-09-01

Family

ID=48668967

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2859773A Active CA2859773C (en) 2011-12-22 2012-12-18 Contrast agent for imagining myocardial perfusion

Country Status (15)

Country Link
US (2) US9295738B2 (enExample)
EP (1) EP2793952B1 (enExample)
JP (1) JP6140187B2 (enExample)
KR (1) KR101931792B1 (enExample)
CN (1) CN104114191A (enExample)
AU (1) AU2012354223B2 (enExample)
BR (1) BR112014015124A2 (enExample)
CA (1) CA2859773C (enExample)
ES (1) ES2687234T3 (enExample)
IL (1) IL233219A (enExample)
MX (1) MX356258B (enExample)
RU (1) RU2629840C2 (enExample)
SG (1) SG11201403429YA (enExample)
WO (1) WO2013095273A1 (enExample)
ZA (1) ZA201405199B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9955876B2 (en) * 2016-09-08 2018-05-01 Raul Chirife Device and method for assessment of left ventricular ejection fraction and other parameters of cardiac performance
CN107233585B (zh) * 2017-06-09 2021-01-22 四川大学华西医院 黄连素或其衍生物在制备心肌灌注显像剂中的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
US7824659B2 (en) 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
US8415333B2 (en) * 2009-02-24 2013-04-09 Respiratorious Ab Bronchodilating diazaheteroaryls

Also Published As

Publication number Publication date
CN104114191A (zh) 2014-10-22
MX356258B (es) 2018-05-16
HK1201459A1 (en) 2015-09-04
US20160101195A1 (en) 2016-04-14
JP2015500873A (ja) 2015-01-08
RU2014125849A (ru) 2016-02-10
US9687565B2 (en) 2017-06-27
IL233219A (en) 2016-08-31
CA2859773A1 (en) 2013-06-27
WO2013095273A1 (en) 2013-06-27
KR101931792B1 (ko) 2019-03-13
ES2687234T3 (es) 2018-10-24
AU2012354223B2 (en) 2017-03-16
EP2793952B1 (en) 2018-06-13
US20140341808A1 (en) 2014-11-20
JP6140187B2 (ja) 2017-05-31
US9295738B2 (en) 2016-03-29
EP2793952A1 (en) 2014-10-29
IL233219A0 (en) 2014-08-31
RU2629840C2 (ru) 2017-09-04
EP2793952A4 (en) 2015-09-09
BR112014015124A2 (pt) 2017-06-13
SG11201403429YA (en) 2014-07-30
KR20140107411A (ko) 2014-09-04
AU2012354223A1 (en) 2014-07-03
MX2014007491A (es) 2015-02-17
ZA201405199B (en) 2015-12-23

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Effective date: 20171027