KR101931792B1 - 심근 관류를 영상화하기 위한 조영제 - Google Patents
심근 관류를 영상화하기 위한 조영제 Download PDFInfo
- Publication number
- KR101931792B1 KR101931792B1 KR1020147018989A KR20147018989A KR101931792B1 KR 101931792 B1 KR101931792 B1 KR 101931792B1 KR 1020147018989 A KR1020147018989 A KR 1020147018989A KR 20147018989 A KR20147018989 A KR 20147018989A KR 101931792 B1 KR101931792 B1 KR 101931792B1
- Authority
- KR
- South Korea
- Prior art keywords
- imaging
- composition
- imaging agent
- patient
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 Cc1c(*)cc(CNC(c2cc(cccn3)c3nc2C)=O)cc1 Chemical compound Cc1c(*)cc(CNC(c2cc(cccn3)c3nc2C)=O)cc1 0.000 description 2
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579113P | 2011-12-22 | 2011-12-22 | |
| SE1151249-8 | 2011-12-22 | ||
| SE1151249 | 2011-12-22 | ||
| US61/579,113 | 2011-12-22 | ||
| PCT/SE2012/051421 WO2013095273A1 (en) | 2011-12-22 | 2012-12-18 | Contrast agent for imagining myocardial perfusion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140107411A KR20140107411A (ko) | 2014-09-04 |
| KR101931792B1 true KR101931792B1 (ko) | 2019-03-13 |
Family
ID=48668967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147018989A Expired - Fee Related KR101931792B1 (ko) | 2011-12-22 | 2012-12-18 | 심근 관류를 영상화하기 위한 조영제 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9295738B2 (enExample) |
| EP (1) | EP2793952B1 (enExample) |
| JP (1) | JP6140187B2 (enExample) |
| KR (1) | KR101931792B1 (enExample) |
| CN (1) | CN104114191A (enExample) |
| AU (1) | AU2012354223B2 (enExample) |
| BR (1) | BR112014015124A2 (enExample) |
| CA (1) | CA2859773C (enExample) |
| ES (1) | ES2687234T3 (enExample) |
| IL (1) | IL233219A (enExample) |
| MX (1) | MX356258B (enExample) |
| RU (1) | RU2629840C2 (enExample) |
| SG (1) | SG11201403429YA (enExample) |
| WO (1) | WO2013095273A1 (enExample) |
| ZA (1) | ZA201405199B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9955876B2 (en) * | 2016-09-08 | 2018-05-01 | Raul Chirife | Device and method for assessment of left ventricular ejection fraction and other parameters of cardiac performance |
| CN107233585B (zh) * | 2017-06-09 | 2021-01-22 | 四川大学华西医院 | 黄连素或其衍生物在制备心肌灌注显像剂中的用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010097410A1 (en) | 2009-02-24 | 2010-09-02 | Respiratorius Ab | Novel bronchodilating diazaheteroaryls |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| US7932272B2 (en) | 2003-09-30 | 2011-04-26 | Eisai R&D Management Co., Ltd. | Antifungal agent containing heterocyclic compound |
| US7824659B2 (en) | 2005-08-10 | 2010-11-02 | Lantheus Medical Imaging, Inc. | Methods of making radiolabeled tracers and precursors thereof |
-
2012
- 2012-12-18 ES ES12858896.9T patent/ES2687234T3/es active Active
- 2012-12-18 EP EP12858896.9A patent/EP2793952B1/en not_active Not-in-force
- 2012-12-18 RU RU2014125849A patent/RU2629840C2/ru active
- 2012-12-18 US US14/367,520 patent/US9295738B2/en not_active Expired - Fee Related
- 2012-12-18 MX MX2014007491A patent/MX356258B/es active IP Right Grant
- 2012-12-18 AU AU2012354223A patent/AU2012354223B2/en not_active Ceased
- 2012-12-18 BR BR112014015124A patent/BR112014015124A2/pt not_active Application Discontinuation
- 2012-12-18 WO PCT/SE2012/051421 patent/WO2013095273A1/en not_active Ceased
- 2012-12-18 CA CA2859773A patent/CA2859773C/en active Active
- 2012-12-18 CN CN201280069796.5A patent/CN104114191A/zh active Pending
- 2012-12-18 JP JP2014548735A patent/JP6140187B2/ja not_active Expired - Fee Related
- 2012-12-18 KR KR1020147018989A patent/KR101931792B1/ko not_active Expired - Fee Related
- 2012-12-18 SG SG11201403429YA patent/SG11201403429YA/en unknown
-
2014
- 2014-06-18 IL IL233219A patent/IL233219A/en active IP Right Grant
- 2014-07-16 ZA ZA2014/05199A patent/ZA201405199B/en unknown
-
2015
- 2015-12-17 US US14/972,127 patent/US9687565B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010097410A1 (en) | 2009-02-24 | 2010-09-02 | Respiratorius Ab | Novel bronchodilating diazaheteroaryls |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104114191A (zh) | 2014-10-22 |
| MX356258B (es) | 2018-05-16 |
| HK1201459A1 (en) | 2015-09-04 |
| US20160101195A1 (en) | 2016-04-14 |
| JP2015500873A (ja) | 2015-01-08 |
| RU2014125849A (ru) | 2016-02-10 |
| US9687565B2 (en) | 2017-06-27 |
| IL233219A (en) | 2016-08-31 |
| CA2859773A1 (en) | 2013-06-27 |
| WO2013095273A1 (en) | 2013-06-27 |
| CA2859773C (en) | 2020-09-01 |
| ES2687234T3 (es) | 2018-10-24 |
| AU2012354223B2 (en) | 2017-03-16 |
| EP2793952B1 (en) | 2018-06-13 |
| US20140341808A1 (en) | 2014-11-20 |
| JP6140187B2 (ja) | 2017-05-31 |
| US9295738B2 (en) | 2016-03-29 |
| EP2793952A1 (en) | 2014-10-29 |
| IL233219A0 (en) | 2014-08-31 |
| RU2629840C2 (ru) | 2017-09-04 |
| EP2793952A4 (en) | 2015-09-09 |
| BR112014015124A2 (pt) | 2017-06-13 |
| SG11201403429YA (en) | 2014-07-30 |
| KR20140107411A (ko) | 2014-09-04 |
| AU2012354223A1 (en) | 2014-07-03 |
| MX2014007491A (es) | 2015-02-17 |
| ZA201405199B (en) | 2015-12-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106977429B (zh) | 用于合成和使用造影剂的组合物、方法和系统 | |
| RU2641285C2 (ru) | Соединения хинина, способ их получения и их медицинское применение | |
| JP6987840B2 (ja) | Ido1酵素イメージングのための放射性リガンド | |
| US20240042066A1 (en) | Fibroblast activation protein inhibitor | |
| CA3116129A1 (en) | Radioligands for imaging the lpa1 receptor | |
| KR20180107243A (ko) | 에리불린의 합성에서의 중간체 및 관련된 합성 방법 | |
| KR101931792B1 (ko) | 심근 관류를 영상화하기 위한 조영제 | |
| CA2911307C (en) | Use of fluorinated derivatives of 4-aminopyridine in therapeutics and medical imaging | |
| US20110150767A1 (en) | Alpha-substituted and alpha-unsubstituted aromatic amino acid derivatives and compositions thereof for use to treat, diagnose, or monitor a medical condition | |
| HK1201459B (en) | Contrast agent for imagining myocardial perfusion | |
| CN102223900A (zh) | 用于多巴胺d2受体的成像配体 | |
| WO2014184682A1 (en) | Radiolabeled gnrh antagonists as pet imaging agents | |
| CN103974947A (zh) | 可用于体内成像的5ht1a拮抗剂 | |
| CN113387896B (zh) | 一种4-(2-氯芳基)喹唑啉-2-酰胺衍生物及其应用 | |
| US20250222145A1 (en) | Tracer composition for radioactive pet diagnosis, intermediate thereof, and production method thereof | |
| JP6041751B2 (ja) | スチリルピリジン誘導体化合物 | |
| KR20140117199A (ko) | 신규한 벤즈아마이드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 피부암 진단용 약학적 조성물 | |
| HK1241356A1 (en) | Compositions, methods and systems for the synthesis and use of imaging agents | |
| JP2014218454A (ja) | スチリルピリジン誘導体化合物 | |
| HK1182933A (en) | Compositions, methods and systems for the synthesis and use of imaging agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| D13-X000 | Search requested |
St.27 status event code: A-1-2-D10-D13-srh-X000 |
|
| D14-X000 | Search report completed |
St.27 status event code: A-1-2-D10-D14-srh-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20221218 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20221218 |