JP6087029B2 - 殺菌方法、殺菌用製剤、および殺菌液の製造装置 - Google Patents
殺菌方法、殺菌用製剤、および殺菌液の製造装置 Download PDFInfo
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- JP6087029B2 JP6087029B2 JP2016546329A JP2016546329A JP6087029B2 JP 6087029 B2 JP6087029 B2 JP 6087029B2 JP 2016546329 A JP2016546329 A JP 2016546329A JP 2016546329 A JP2016546329 A JP 2016546329A JP 6087029 B2 JP6087029 B2 JP 6087029B2
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- Prior art keywords
- acid
- liquid
- pernitric
- sterilization
- nitrite
- Prior art date
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- 239000002253 acid Substances 0.000 claims description 209
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 57
- 150000002978 peroxides Chemical class 0.000 claims description 48
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 claims description 44
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 claims description 38
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims description 33
- 229910017604 nitric acid Inorganic materials 0.000 claims description 33
- 238000003786 synthesis reaction Methods 0.000 claims description 31
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- 239000002243 precursor Substances 0.000 claims description 22
- 235000010288 sodium nitrite Nutrition 0.000 claims description 19
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 claims description 14
- 238000001816 cooling Methods 0.000 claims description 11
- 239000007853 buffer solution Substances 0.000 claims description 10
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- CMFNMSMUKZHDEY-UHFFFAOYSA-N peroxynitrous acid Chemical compound OON=O CMFNMSMUKZHDEY-UHFFFAOYSA-N 0.000 description 18
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- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 10
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- AZFNGPAYDKGCRB-XCPIVNJJSA-M [(1s,2s)-2-amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;chlororuthenium(1+);1-methyl-4-propan-2-ylbenzene Chemical compound [Ru+]Cl.CC(C)C1=CC=C(C)C=C1.C1=CC(C)=CC=C1S(=O)(=O)[N-][C@@H](C=1C=CC=CC=1)[C@@H](N)C1=CC=CC=C1 AZFNGPAYDKGCRB-XCPIVNJJSA-M 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 4
- ZWWCURLKEXEFQT-UHFFFAOYSA-N dinitrogen pentaoxide Chemical compound [O-][N+](=O)O[N+]([O-])=O ZWWCURLKEXEFQT-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
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- UUZZMWZGAZGXSF-UHFFFAOYSA-N peroxynitric acid Chemical compound OON(=O)=O UUZZMWZGAZGXSF-UHFFFAOYSA-N 0.000 description 4
- RAFRTSDUWORDLA-UHFFFAOYSA-N phenyl 3-chloropropanoate Chemical compound ClCCC(=O)OC1=CC=CC=C1 RAFRTSDUWORDLA-UHFFFAOYSA-N 0.000 description 4
- 239000004304 potassium nitrite Substances 0.000 description 4
- XXQBEVHPUKOQEO-UHFFFAOYSA-N potassium superoxide Chemical compound [K+].[K+].[O-][O-] XXQBEVHPUKOQEO-UHFFFAOYSA-N 0.000 description 4
- 238000012795 verification Methods 0.000 description 4
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 229910002651 NO3 Inorganic materials 0.000 description 3
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 3
- 206010052428 Wound Diseases 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
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- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 description 3
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- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
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- 230000036760 body temperature Effects 0.000 description 2
- LHJQIRIGXXHNLA-UHFFFAOYSA-N calcium peroxide Chemical compound [Ca+2].[O-][O-] LHJQIRIGXXHNLA-UHFFFAOYSA-N 0.000 description 2
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- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 2
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- 239000000843 powder Substances 0.000 description 2
- 238000013319 spin trapping Methods 0.000 description 2
- OSKIWEPJAIOTFB-UHFFFAOYSA-N 5,5-dimethyl-2-(2-methyl-1-oxido-3,4-dihydropyrrol-1-ium-2-yl)-1,3,2$l^{5}-dioxaphosphinane 2-oxide Chemical compound O1CC(C)(C)COP1(=O)C1(C)CCC=[N+]1[O-] OSKIWEPJAIOTFB-UHFFFAOYSA-N 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
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- VTIIJXUACCWYHX-UHFFFAOYSA-L disodium;carboxylatooxy carbonate Chemical compound [Na+].[Na+].[O-]C(=O)OOC([O-])=O VTIIJXUACCWYHX-UHFFFAOYSA-L 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Virology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Treatment Of Water By Oxidation Or Reduction (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014178467 | 2014-09-02 | ||
| JP2014178467 | 2014-09-02 | ||
| PCT/JP2015/004470 WO2016035342A1 (fr) | 2014-09-02 | 2015-09-02 | Procédé de stérilisation, préparation pour stérilisation, et dispositif de production d'un liquide bactéricide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP6087029B2 true JP6087029B2 (ja) | 2017-03-01 |
| JPWO2016035342A1 JPWO2016035342A1 (ja) | 2017-04-27 |
Family
ID=55439421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016546329A Active JP6087029B2 (ja) | 2014-09-02 | 2015-09-02 | 殺菌方法、殺菌用製剤、および殺菌液の製造装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10499648B2 (fr) |
| EP (1) | EP3189857B1 (fr) |
| JP (1) | JP6087029B2 (fr) |
| ES (1) | ES2848860T3 (fr) |
| WO (1) | WO2016035342A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023127825A1 (fr) | 2021-12-28 | 2023-07-06 | 国立大学法人大阪大学 | Procédé de stérilisation et dispositif de stérilisation |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019219220A1 (fr) * | 2018-05-18 | 2019-11-21 | Leibniz-Institut für Plasmaforschung und Technologie e.V. | Procédé de désinfection comprenant un principe actif désinfectant formé in situ par réaction de h2o2 et de no2- |
| JP7179289B2 (ja) * | 2018-11-30 | 2022-11-29 | 地方独立行政法人大阪産業技術研究所 | 過硝酸の濃度検出方法および装置、並びに殺菌用過硝酸の生成装置 |
| EP3789045A1 (fr) * | 2019-09-04 | 2021-03-10 | Leibniz-Institut für Plasmaforschung und Technologie e.V. | Procédé de désinfection au moyen d'une substance active de désinfection formée par la réaction du h2o2 et du no2 in situ à libération retardée |
| JP2021155362A (ja) * | 2020-03-27 | 2021-10-07 | 株式会社ナリス化粧品 | ペルオキシナイトライト活性阻害方法および、ペルオキシナイトライト活性阻害剤のスクリーニング方法 |
| WO2023182417A1 (fr) * | 2022-03-25 | 2023-09-28 | 国立大学法人大阪大学 | Dispositif de traitement de plaie et revêtement de plaie utilisé dans ce contexte |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0725178A (ja) * | 1993-07-08 | 1995-01-27 | Konica Corp | 感光性平版印刷版の処理方法及び処理装置 |
| WO2006079109A2 (fr) * | 2005-01-21 | 2006-07-27 | Rdx Technologies, Inc. | Compositions antimicrobiennes non toxiques, et procedes d'utilisation de polyphenols pro-oxydatifs et d'antioxydants |
| WO2009041049A1 (fr) * | 2007-09-27 | 2009-04-02 | Satoshi Ikawa | Procédé et appareil de pasteurisation |
| WO2011027542A1 (fr) * | 2009-09-03 | 2011-03-10 | 国立大学法人大阪大学 | Procédé et dispositif pour introduire des ions dans un liquide, et procédé et dispositif de stérilisation |
| WO2013105659A1 (fr) * | 2012-01-13 | 2013-07-18 | 国立大学法人大阪大学 | Dispositif d'irradiation d'une espèce active, procédé d'irradiation d'une espèce active et procédé de formation d'un objet ayant été irradié avec une espèce active |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3364037A (en) * | 1965-08-03 | 1968-01-16 | Swift & Co | Hydrogen peroxide treatment of eggs |
| US3593928A (en) * | 1969-08-20 | 1971-07-20 | Millmaster Onyx Corp | System for producing printing inks |
| US3677963A (en) | 1970-09-30 | 1972-07-18 | Diamond Shamrock Corp | Defoamer composition and method of preparation |
| JP2002326922A (ja) | 2001-03-01 | 2002-11-15 | Kose Corp | 皮膚外用剤 |
| JP2002265387A (ja) | 2001-03-06 | 2002-09-18 | Kose Corp | 皮膚外用剤 |
| JP4837249B2 (ja) | 2003-12-11 | 2011-12-14 | 株式会社ナリス化粧品 | ニトロチロシン生成阻害剤・ペルオキシナイトライト阻害剤 |
| WO2008072390A1 (fr) | 2006-12-12 | 2008-06-19 | Osaka Industrial Promotion Organization | Appareil de production de plasma et procédé de production de plasma |
| JPWO2013161327A1 (ja) | 2012-04-27 | 2015-12-24 | 国立大学法人大阪大学 | 殺菌処理方法、殺菌用製剤、殺菌用結氷体およびその生成方法および装置、並びに殺菌用液体の生成方法 |
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2015
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH0725178A (ja) * | 1993-07-08 | 1995-01-27 | Konica Corp | 感光性平版印刷版の処理方法及び処理装置 |
| WO2006079109A2 (fr) * | 2005-01-21 | 2006-07-27 | Rdx Technologies, Inc. | Compositions antimicrobiennes non toxiques, et procedes d'utilisation de polyphenols pro-oxydatifs et d'antioxydants |
| WO2009041049A1 (fr) * | 2007-09-27 | 2009-04-02 | Satoshi Ikawa | Procédé et appareil de pasteurisation |
| WO2011027542A1 (fr) * | 2009-09-03 | 2011-03-10 | 国立大学法人大阪大学 | Procédé et dispositif pour introduire des ions dans un liquide, et procédé et dispositif de stérilisation |
| WO2013105659A1 (fr) * | 2012-01-13 | 2013-07-18 | 国立大学法人大阪大学 | Dispositif d'irradiation d'une espèce active, procédé d'irradiation d'une espèce active et procédé de formation d'un objet ayant été irradié avec une espèce active |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023127825A1 (fr) | 2021-12-28 | 2023-07-06 | 国立大学法人大阪大学 | Procédé de stérilisation et dispositif de stérilisation |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3189857A1 (fr) | 2017-07-12 |
| EP3189857B1 (fr) | 2020-11-04 |
| JPWO2016035342A1 (ja) | 2017-04-27 |
| US10499648B2 (en) | 2019-12-10 |
| ES2848860T3 (es) | 2021-08-12 |
| EP3189857A4 (fr) | 2018-09-12 |
| WO2016035342A1 (fr) | 2016-03-10 |
| US20170172149A1 (en) | 2017-06-22 |
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