JP6084172B2 - 酸化感受性材料の統合的な触媒による保護 - Google Patents

酸化感受性材料の統合的な触媒による保護 Download PDF

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Publication number
JP6084172B2
JP6084172B2 JP2013558170A JP2013558170A JP6084172B2 JP 6084172 B2 JP6084172 B2 JP 6084172B2 JP 2013558170 A JP2013558170 A JP 2013558170A JP 2013558170 A JP2013558170 A JP 2013558170A JP 6084172 B2 JP6084172 B2 JP 6084172B2
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sensor
graft
porous
indicator
protective coating
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JP2014514033A (ja
JP2014514033A5 (https=
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コルヴィン,アーサー・イー,ジュニア
ジアン,ホイ
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センセオニクス,インコーポレーテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/07Endoradiosondes
    • A61B5/076Permanent implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/028Microscale sensors, e.g. electromechanical sensors [MEMS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/162Capsule shaped sensor housings, e.g. for swallowing or implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/18Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrotherapy Devices (AREA)
JP2013558170A 2011-03-15 2012-03-15 酸化感受性材料の統合的な触媒による保護 Expired - Fee Related JP6084172B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161452893P 2011-03-15 2011-03-15
US61/452,893 2011-03-15
US201161527368P 2011-08-25 2011-08-25
US61/527,368 2011-08-25
PCT/US2012/029209 WO2012125814A2 (en) 2011-03-15 2012-03-15 Integrated catalytic protection of oxidation sensitive materials

Publications (3)

Publication Number Publication Date
JP2014514033A JP2014514033A (ja) 2014-06-19
JP2014514033A5 JP2014514033A5 (https=) 2016-09-15
JP6084172B2 true JP6084172B2 (ja) 2017-02-22

Family

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JP2013558170A Expired - Fee Related JP6084172B2 (ja) 2011-03-15 2012-03-15 酸化感受性材料の統合的な触媒による保護

Country Status (10)

Country Link
US (2) US9681824B2 (https=)
EP (1) EP2685884B1 (https=)
JP (1) JP6084172B2 (https=)
KR (1) KR101959067B1 (https=)
CN (1) CN103533884B (https=)
AU (1) AU2012229109A1 (https=)
CA (1) CA2830432C (https=)
SG (1) SG193496A1 (https=)
TW (1) TWI592663B (https=)
WO (1) WO2012125814A2 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10201935B2 (en) 2007-03-19 2019-02-12 Augustine Temperature Management LLC Electric heating pad
US8283602B2 (en) 2007-03-19 2012-10-09 Augustine Temperature Management LLC Heating blanket
US20150366367A1 (en) 2007-03-19 2015-12-24 Augustine Temperature Management LLC Electric heating pad with electrosurgical grounding
EP2685884B1 (en) 2011-03-15 2020-09-23 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
US20140088383A1 (en) * 2012-09-14 2014-03-27 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
US11109779B2 (en) 2012-12-28 2021-09-07 Senseonics, Incorporated Chemical modification of analyte permeable membrane for enhanced oxidative stability
JP2016508761A (ja) 2012-12-28 2016-03-24 センセオニクス,インコーポレーテッド 酸化及び光学的安定性のための分析物浸透膜システム
WO2015027018A1 (en) * 2013-08-21 2015-02-26 Senseonics, Incorporated Drug elution for in vivo protection of bio-sensing analytes
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
JP6732654B2 (ja) * 2014-02-19 2020-07-29 マリンクロット ホスピタル プロダクツ アイピー リミテッド 一酸化窒素に曝される電気化学ガスセンサーの長期の感度変動を補償する方法
WO2015157684A1 (en) 2014-04-10 2015-10-15 Augustine Biomedical And Design, Llc Underbody warming systems with core temperature monitoring
WO2016077742A1 (en) 2014-11-13 2016-05-19 Augustine Temperature Management, Llc Heated underbody warming systems with electrosurgical grounding
US10553861B2 (en) 2017-04-10 2020-02-04 HHeLI, LLC Battery with novel components
US9786910B2 (en) 2015-11-16 2017-10-10 HHeLI, LLC Synthesized, surface-functionalized, acidified metal oxide materials for energy storage, catalytic, photovoltaic and sensor applications
WO2020252389A1 (en) 2019-06-12 2020-12-17 HHeLI, LLC Blended active materials for battery cells
US20180000997A1 (en) * 2016-06-29 2018-01-04 Berlock Aps Implantable Device Having an Outer Surface Comprising Gold and Its Use as an Anti-Migration Device
WO2018075657A1 (en) 2016-10-18 2018-04-26 Senseonics, Incorporated Real time assessement of sensor performance and prediction of the end of the functional life of an implanted sensor
WO2018093945A1 (en) 2016-11-15 2018-05-24 Hheli, Llc. A surface-functionalized, acidified metal oxide material in an acidified electrolyte system or an acidified electrode system
US12369824B2 (en) 2017-04-19 2025-07-29 Senseonics, Incorporated Detecting and correcting for interference in an analyte monitoring system
CN115868982B (zh) 2017-04-19 2025-10-10 传感技术股份有限公司 对分析物指示剂变化的检测和修正
CA3172066A1 (en) 2017-05-17 2018-11-22 HHeLI, LLC Battery with acidified cathode and lithium anode
CA3062617C (en) 2017-05-17 2023-09-19 HHeLI, LLC A high capacity battery cell with low active material loading
US10978731B2 (en) 2017-06-21 2021-04-13 HHeLI, LLC Ultra high capacity performance battery cell
KR102502966B1 (ko) 2017-09-22 2023-02-23 에이치헬리, 엘엘씨 초 고용량 성능의 배터리 셀의 구성
WO2019108641A1 (en) * 2017-11-28 2019-06-06 Senseonics, Incorporated Analyte indicator integrated with a catalytically active material
KR102098078B1 (ko) * 2018-07-13 2020-04-08 주식회사 엔게인 수화겔 및 이를 포함하는 글루코스 센서
US11283267B2 (en) 2018-09-10 2022-03-22 HHeLI, LLC Methods of use of ultra high capacity performance battery cell
JP7394850B2 (ja) * 2018-11-02 2023-12-08 センセオニクス,インコーポレーテッド 分析物指示薬上の薬剤溶出マトリクス
EP3891498B1 (en) * 2018-12-05 2025-04-30 Senseonics, Incorporated Reduction of in vivo analyte signal degradation using multiple metals
US10765580B1 (en) 2019-03-27 2020-09-08 Augustine Biomedical And Design, Llc Patient securement system for the surgical trendelenburg position
EP3965657B1 (en) 2019-05-08 2025-03-05 Senseonics, Incorporated Mediation of in vivo analyte signal degradation
US11963761B2 (en) 2019-05-16 2024-04-23 Senseonics, Incorporated Mediation of in vivo analyte signal degradation
US12278342B2 (en) 2019-06-12 2025-04-15 HHeLI, LLC Alkaline and acidified metal oxide blended active materials
EP4049032A1 (en) 2019-10-25 2022-08-31 Cercacor Laboratories, Inc. Indicator compounds, devices comprising indicator compounds, and methods of making and using the same
IL273038B (en) 2020-03-03 2022-02-01 Ben Zion Karmon bone graft
WO2023249893A1 (en) 2022-06-23 2023-12-28 Augustine Biomedical And Design, Llc Patient securement system for the surgical trendelenburg position
US11844733B1 (en) 2022-06-23 2023-12-19 Augustine Biomedical And Design, Llc Patient securement system for the surgical Trendelenburg position
US20240260861A1 (en) * 2023-02-06 2024-08-08 Senseonics, Incorporated Reduction of in vivo analyte signal degradation using multiple metals
CN116392648B (zh) * 2023-04-14 2024-08-23 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
US12458257B2 (en) 2024-04-12 2025-11-04 Glucotrack, Inc. Implantable glucose sensors and methods of glucose measurement configured for minimal sensor surface obstruction
US20250387054A1 (en) * 2024-06-25 2025-12-25 Senseonics, Incorporated Preventing yellowing and fluorescence in epoxide diamine networks

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63291595A (ja) * 1987-05-22 1988-11-29 Meidensha Electric Mfg Co Ltd 生体試料中のグルコ−スの測定方法
US5517313A (en) 1995-02-21 1996-05-14 Colvin, Jr.; Arthur E. Fluorescent optical sensor
US5772864A (en) 1996-02-23 1998-06-30 Meadox Medicals, Inc. Method for manufacturing implantable medical devices
US5833603A (en) 1996-03-13 1998-11-10 Lipomatrix, Inc. Implantable biosensing transponder
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US5910661A (en) 1997-05-13 1999-06-08 Colvin, Jr.; Arthur E. Flourescence sensing device
US5894351A (en) 1997-05-13 1999-04-13 Colvin, Jr.; Arthur E. Fluorescence sensing device
US5917605A (en) 1997-05-13 1999-06-29 Colvin, Jr.; Arthur E. Fluorescence sensing device
US5922183A (en) 1997-06-23 1999-07-13 Eic Laboratories, Inc. Metal oxide matrix biosensors
ES2227880T3 (es) 1997-08-09 2005-04-01 Roche Diagnostics Gmbh Dispositivo de analisis para realizar analisis in vivo en el cuerpo de un paciente.
WO1999046600A1 (en) 1998-03-11 1999-09-16 Sensors For Medicine And Science, Inc. Detection of analytes by fluorescent lanthanide chelates
US6304766B1 (en) 1998-08-26 2001-10-16 Sensors For Medicine And Science Optical-based sensing devices, especially for in-situ sensing in humans
CN100385232C (zh) 1998-08-26 2008-04-30 医药及科学传感器公司 基于光学的感测装置
DE19855421C2 (de) * 1998-11-02 2001-09-20 Alcove Surfaces Gmbh Implantat
US6189536B1 (en) * 1999-04-15 2001-02-20 Medtronic Inc. Method for protecting implantable devices
US6400974B1 (en) 2000-06-29 2002-06-04 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method for processing implanted sensor output
US7553280B2 (en) 2000-06-29 2009-06-30 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method
KR100922146B1 (ko) 2000-08-04 2009-10-19 센서즈 포 메드슨 앤드 사이언스 인코포레이티드 수성 환경에서의 분석물 검출
US7470420B2 (en) * 2000-12-05 2008-12-30 The Regents Of The University Of California Optical determination of glucose utilizing boronic acid adducts
US6800451B2 (en) 2001-01-05 2004-10-05 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
MXPA03010064A (es) 2001-05-04 2004-03-09 Sensors For Med & Science Inc Dispositivo de deteccion electro-optico con canal de referencia.
TWI293363B (en) 2001-12-11 2008-02-11 Sensors For Med & Science Inc High performance fluorescent optical sensor
KR20030055609A (ko) 2001-12-27 2003-07-04 김재열 꼬임 방지형 원주 자동 용접장치
SE0200269D0 (sv) * 2002-01-31 2002-01-31 Ellem Bioteknik Ab Material for implantation
US20040063167A1 (en) 2002-07-12 2004-04-01 Peter Kaastrup Minimising calibration problems of in vivo glucose sensors
CN1806475B (zh) 2003-04-15 2013-07-03 医药及科学传感器公司 具有集成天线的印刷电路装置和具有集成印刷电路板天线的可植入传感器处理系统
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8282549B2 (en) 2003-12-09 2012-10-09 Dexcom, Inc. Signal processing for continuous analyte sensor
US7519408B2 (en) 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US20050095174A1 (en) * 2003-10-31 2005-05-05 Wolf David E. Semipermeable sensors for detecting analyte
US8095197B2 (en) 2003-11-03 2012-01-10 Microchips, Inc. Medical device for sensing glucose
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
JP2005315871A (ja) * 2004-03-31 2005-11-10 Terumo Corp 体内物質測定用構成物、体内物質測定用構成物の製造方法、および埋込型物質センサー
US7450980B2 (en) 2004-03-31 2008-11-11 Terumo Kabushiki Kaisha Intracorporeal substance measuring assembly
US7713745B2 (en) * 2004-04-13 2010-05-11 Sensors For Medicine And Science, Inc. Non-covalent immobilization of indicator molecules
US20050234316A1 (en) 2004-04-16 2005-10-20 Sensors For Medicine And Science, Inc. Housing for a circuit that is to be implanted in-vivo and process of making the same
US7375347B2 (en) 2004-04-26 2008-05-20 Sensors For Medicine And Science, Inc. Systems and methods for extending the useful life of optical sensors
US20070045902A1 (en) 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US7783333B2 (en) * 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US8073548B2 (en) 2004-08-24 2011-12-06 Sensors For Medicine And Science, Inc. Wristband or other type of band having an adjustable antenna for use with a sensor reader
US8308794B2 (en) * 2004-11-15 2012-11-13 IZEK Technologies, Inc. Instrumented implantable stents, vascular grafts and other medical devices
US7308292B2 (en) 2005-04-15 2007-12-11 Sensors For Medicine And Science, Inc. Optical-based sensing devices
US20060282042A1 (en) 2005-06-08 2006-12-14 Sensors For Medicine And Science, Inc. Insertion device and method
US20070014726A1 (en) 2005-07-18 2007-01-18 Sensors For Medicine And Science Oxidation-resistant indicator macromolecule
EP1790977A1 (en) 2005-11-23 2007-05-30 SONY DEUTSCHLAND GmbH Nanoparticle/nanofiber based chemical sensor, arrays of such sensors, uses and method of fabrication thereof, and method of detecting an analyte
US20100202966A1 (en) 2006-03-28 2010-08-12 Yossi Gross Implantable Sensor
US20080125838A1 (en) 2006-08-10 2008-05-29 Medtronic, Inc. Implantable Devices With Photocatalytic Surfaces
CN101541813B (zh) 2006-11-30 2013-07-31 医药及科学传感器公司 耐氧化的指示剂分子
KR20090127344A (ko) 2007-03-08 2009-12-10 센서즈 포 메드슨 앤드 사이언스 인코포레이티드 가혹한 환경용 발광 다이오드
CA2686065A1 (en) * 2007-05-10 2008-11-20 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
AU2009276832A1 (en) 2008-07-28 2010-02-04 Sensors For Medicine & Science, Inc. Systems and methods for optical measurement of analyte concentration
EP4549933A3 (en) 2008-09-19 2025-05-21 DexCom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
CA2757842A1 (en) * 2009-04-09 2010-10-14 The Children's Hospital Of Philadelphia Ligand-specific inhibition of attachment of immune cells to implantable biomaterials
WO2010123972A1 (en) 2009-04-21 2010-10-28 Sensors For Medicine And Science, Inc. Protective shell for an in vivo sensor made from resorbable polymer
WO2011097586A1 (en) * 2010-02-08 2011-08-11 Glumetrics, Inc. Antioxidant protection of a chemical sensor
JP6008370B2 (ja) 2010-02-16 2016-10-19 ライトシップ メディカル リミテッド グルコースセンサ用障壁層
JP5101659B2 (ja) * 2010-05-25 2012-12-19 株式会社東芝 血圧センサ
US20120053427A1 (en) 2010-08-31 2012-03-01 Glumetrics, Inc. Optical sensor configuration and methods for monitoring glucose activity in interstitial fluid
WO2012048150A1 (en) 2010-10-06 2012-04-12 Profusa, Inc. Tissue-integrating sensors
EP2685884B1 (en) 2011-03-15 2020-09-23 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
EP2744909B1 (en) 2011-08-17 2021-09-22 Baxter International Inc. Method for preparing a barrier layer for a glucose sensor
CA3095821C (en) 2012-03-15 2023-03-14 Baxter International Inc. Sensor

Also Published As

Publication number Publication date
WO2012125814A2 (en) 2012-09-20
US20180146885A1 (en) 2018-05-31
CN103533884A (zh) 2014-01-22
WO2012125814A3 (en) 2013-12-27
EP2685884A2 (en) 2014-01-22
AU2012229109A1 (en) 2013-10-10
US20120238842A1 (en) 2012-09-20
JP2014514033A (ja) 2014-06-19
KR20140035892A (ko) 2014-03-24
CN103533884B (zh) 2016-06-01
CA2830432A1 (en) 2012-09-20
US10674937B2 (en) 2020-06-09
EP2685884B1 (en) 2020-09-23
TW201243332A (en) 2012-11-01
CA2830432C (en) 2022-04-26
EP2685884A4 (en) 2015-04-15
US9681824B2 (en) 2017-06-20
KR101959067B1 (ko) 2019-03-15
TWI592663B (zh) 2017-07-21
SG193496A1 (en) 2013-10-30

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