JP6078067B2 - 炎症誘発性状態の治療および予防のためのhdl関連分子の使用 - Google Patents

炎症誘発性状態の治療および予防のためのhdl関連分子の使用 Download PDF

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JP6078067B2
JP6078067B2 JP2014528563A JP2014528563A JP6078067B2 JP 6078067 B2 JP6078067 B2 JP 6078067B2 JP 2014528563 A JP2014528563 A JP 2014528563A JP 2014528563 A JP2014528563 A JP 2014528563A JP 6078067 B2 JP6078067 B2 JP 6078067B2
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cells
hdl
hif
mice
peptide
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JP2014526440A (ja
JP2014526440A5 (enExample
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ロビン ファリアス‐アイスナー
ロビン ファリアス‐アイスナー
シュリニヴァーサ ティー. レディ
シュリニヴァーサ ティー. レディ
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University of California
University of California, Los Angeles
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University of California, San Diego
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2014528563A 2011-08-29 2012-08-29 炎症誘発性状態の治療および予防のためのhdl関連分子の使用 Expired - Fee Related JP6078067B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161528447P 2011-08-29 2011-08-29
US61/528,447 2011-08-29
US201261624333P 2012-04-15 2012-04-15
US61/624,333 2012-04-15
US201261646772P 2012-05-14 2012-05-14
US61/646,772 2012-05-14
PCT/US2012/052925 WO2013033260A1 (en) 2011-08-29 2012-08-29 Use of hdl-related molecules to treat and prevent proinflammatory conditions

Publications (3)

Publication Number Publication Date
JP2014526440A JP2014526440A (ja) 2014-10-06
JP2014526440A5 JP2014526440A5 (enExample) 2016-02-12
JP6078067B2 true JP6078067B2 (ja) 2017-02-08

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JP2014528563A Expired - Fee Related JP6078067B2 (ja) 2011-08-29 2012-08-29 炎症誘発性状態の治療および予防のためのhdl関連分子の使用

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US (2) US9241976B2 (enExample)
EP (1) EP2751126B1 (enExample)
JP (1) JP6078067B2 (enExample)
KR (1) KR20140063747A (enExample)
CN (1) CN104039810A (enExample)
AU (1) AU2012301955A1 (enExample)
CA (1) CA2846865A1 (enExample)
WO (1) WO2013033260A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10426817B2 (en) 2017-01-24 2019-10-01 Macregen, Inc. Treatment of age-related macular degeneration and other eye diseases with apolipoprotein mimetics
WO2018190896A1 (en) * 2017-04-13 2018-10-18 Lipimetix Development, Inc. Apoe mimetic peptide compositions
CN120085016A (zh) * 2025-03-14 2025-06-03 北京大学第三医院(北京大学第三临床医学院) 一种apoa1作为生物标志物在制备用于监测结肠炎症活动度的产品中的应用

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Publication number Publication date
KR20140063747A (ko) 2014-05-27
WO2013033260A1 (en) 2013-03-07
US20170204160A1 (en) 2017-07-20
AU2012301955A1 (en) 2014-03-06
US10208103B2 (en) 2019-02-19
US20140323410A1 (en) 2014-10-30
EP2751126A1 (en) 2014-07-09
EP2751126B1 (en) 2018-03-07
CA2846865A1 (en) 2013-03-07
EP2751126A4 (en) 2015-11-04
CN104039810A (zh) 2014-09-10
JP2014526440A (ja) 2014-10-06
US9241976B2 (en) 2016-01-26

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