JP6069755B2 - 高親和性t細胞受容体およびその用途 - Google Patents

高親和性t細胞受容体およびその用途 Download PDF

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JP6069755B2
JP6069755B2 JP2011536895A JP2011536895A JP6069755B2 JP 6069755 B2 JP6069755 B2 JP 6069755B2 JP 2011536895 A JP2011536895 A JP 2011536895A JP 2011536895 A JP2011536895 A JP 2011536895A JP 6069755 B2 JP6069755 B2 JP 6069755B2
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シェンデル、ドロレス
ヴィルデ、ズザンネ
フランケンベルガー、ベルンハルト
ウッケルト、ヴォルフガング
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ヘルムホルツ・ツェントルム・ミュンヘン・ドイチェス・フォーシュンクスツェントルム・フュア・ゲズントハイト・ウント・ウンベルト・ゲーエムベーハー
マックス−デルブリュック−ツェントルム フューア モレキュラーレ メディツィン
マックス−デルブリュック−ツェントルム フューア モレキュラーレ メディツィン
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32T-cell receptors [TCR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4244Enzymes
    • A61K40/4245Tyrosinase or tyrosinase related proteinases [TRP-1 or TRP-2]
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C07ORGANIC CHEMISTRY
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    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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JP2011536895A 2008-11-24 2009-11-24 高親和性t細胞受容体およびその用途 Active JP6069755B2 (ja)

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EP08020396 2008-11-24
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PCT/EP2009/065705 WO2010058023A1 (en) 2008-11-24 2009-11-24 High affinity t cell receptor and use thereof

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