JP6054405B2 - 培養期間を用いた磁性粒子の検出 - Google Patents

培養期間を用いた磁性粒子の検出 Download PDF

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Publication number
JP6054405B2
JP6054405B2 JP2014536360A JP2014536360A JP6054405B2 JP 6054405 B2 JP6054405 B2 JP 6054405B2 JP 2014536360 A JP2014536360 A JP 2014536360A JP 2014536360 A JP2014536360 A JP 2014536360A JP 6054405 B2 JP6054405 B2 JP 6054405B2
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detection surface
magnetic particles
culture period
sensor device
sample chamber
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Japanese (ja)
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JP2014531029A (ja
Inventor
シッケ フォッペン
シッケ フォッペン
ベルナルドス ヨセフ マリア ベールリンフ
ベルナルドス ヨセフ マリア ベールリンフ
クール ウィレミナ マリア フイネン
クール ウィレミナ マリア フイネン
フラーフ ヘンドリク ヤン デ
フラーフ ヘンドリク ヤン デ
ファン デ ウィール ダニーレ ワルテラ マリア ケムペール
ファン デ ウィール ダニーレ ワルテラ マリア ケムペール
ローランド アントニウス ヨハネス ヘラルドス スミッツ
ローランド アントニウス ヨハネス ヘラルドス スミッツ
アルベルト ヘンドリク ヤン イミンク
アルベルト ヘンドリク ヤン イミンク
ティエ フェムケ カリナ デ
ティエ フェムケ カリナ デ
ウエンデラ メールテンス
ウエンデラ メールテンス
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A61B5/064—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/6804—Garments; Clothes
    • A61B5/6805—Vests, e.g. shirts or gowns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Human Computer Interaction (AREA)
  • Dentistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Physiology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2014536360A 2011-10-20 2012-10-05 培養期間を用いた磁性粒子の検出 Active JP6054405B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161549428P 2011-10-20 2011-10-20
US61/549,428 2011-10-20
PCT/IB2012/055355 WO2013057616A1 (en) 2011-10-20 2012-10-05 Magnetic particle detection with incubation period

Publications (2)

Publication Number Publication Date
JP2014531029A JP2014531029A (ja) 2014-11-20
JP6054405B2 true JP6054405B2 (ja) 2016-12-27

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JP2014536360A Active JP6054405B2 (ja) 2011-10-20 2012-10-05 培養期間を用いた磁性粒子の検出

Country Status (6)

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US (2) US10031132B2 (enExample)
EP (1) EP2745118B1 (enExample)
JP (1) JP6054405B2 (enExample)
CN (1) CN103890588B (enExample)
IN (1) IN2014CN02659A (enExample)
WO (1) WO2013057616A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105266765A (zh) * 2014-11-10 2016-01-27 北京至感传感器技术研究院有限公司 用于检测乳房生理变化的装置
US10235737B2 (en) * 2015-05-11 2019-03-19 Elwha Llc Interactive surgical drape, system, and related methods
US10226219B2 (en) * 2015-05-11 2019-03-12 Elwha Llc Interactive surgical drape, system, and related methods
CN105929149B (zh) * 2016-04-26 2018-09-11 中国科学院电子学研究所 一种基于磁富集和全内反射的光学检测仪
JP7455529B2 (ja) * 2019-08-01 2024-03-26 キヤノンメディカルシステムズ株式会社 検体測定装置及び検体測定装置の制御方法
US11136543B1 (en) 2020-02-11 2021-10-05 Edward R. Flynn Magnetic cell incubation device
WO2024057310A1 (en) * 2022-09-13 2024-03-21 Marrow Wiz Ltd. Entry point identification system

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US6319670B1 (en) * 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
JP3647587B2 (ja) * 1997-01-20 2005-05-11 シスメックス株式会社 免疫測定法
US6180418B1 (en) * 1998-01-20 2001-01-30 The United States Of America As Represented By The Secretary Of The Navy Force discrimination assay
US6816266B2 (en) * 2000-02-08 2004-11-09 Deepak Varshneya Fiber optic interferometric vital sign monitor for use in magnetic resonance imaging, confined care facilities and in-hospital
EP1469311B1 (en) 2002-01-29 2007-08-08 Asahi Kasei Kabushiki Kaisha Biosensor, magnetic molecule measurement method, and measurement object measuring method
US7736889B2 (en) * 2003-06-10 2010-06-15 The United States Of America As Represented By The Secretary Of The Navy Fluidic force discrimination
FR2858758B1 (fr) * 2003-08-14 2006-04-07 Tam Telesante Sarl Systeme de surveillance medicale au moyen d'un vetement
WO2007029192A1 (en) * 2005-09-08 2007-03-15 Koninklijke Philips Electronics N. V. Microsensor device
US8637317B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Method of washing beads
WO2008010110A1 (en) * 2006-07-17 2008-01-24 Koninklijke Philips Electronics N. V. Attraction and repulsion of magnetic of magnetizable objects to and from a sensor surface
JP2010500549A (ja) 2006-08-09 2010-01-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ バイオセンサ用の磁気システム
WO2008114025A1 (en) * 2007-03-21 2008-09-25 University Of The West Of England, Bristol Particle facilitated testing
WO2008142492A1 (en) * 2007-05-22 2008-11-27 Koninklijke Philips Electronics N.V. Method for detecting label particles
US20100187450A1 (en) 2007-06-21 2010-07-29 Koninklijke Philips Electronics N.V. Microelectronic sensor device with light source and light detector
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
CN101903758B (zh) * 2007-12-20 2013-05-08 皇家飞利浦电子股份有限公司 用于目标颗粒检测的微电子传感器装置
WO2010042242A1 (en) 2008-10-10 2010-04-15 Rutgers, The State University Of New Jersey Methods and related devices for continuous sensing utilizing magnetic beads
JP5996868B2 (ja) * 2008-10-17 2016-09-21 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 高感度アッセイのためのパルス磁気作動
EP2473595A4 (en) * 2009-08-31 2013-04-24 Mbio Diagnostics Inc INTEGRATED SAMPLE PREPARATION AND ANALYTE IDENTIFICATION
EP2720060A1 (en) 2009-09-28 2014-04-16 Koninklijke Philips N.V. A biosensor system for single particle detection
WO2011147879A1 (en) * 2010-05-27 2011-12-01 Episentec Ab Improved method of sensor measurement
EP2586041A1 (en) * 2010-06-22 2013-05-01 Koninklijke Philips Electronics N.V. Detection of magnetic particles and their clustering
US20120077184A1 (en) * 2010-09-28 2012-03-29 Starkdx Incorporated Electromagnetic multiplex assay biosensor

Also Published As

Publication number Publication date
US20140323856A1 (en) 2014-10-30
US10031132B2 (en) 2018-07-24
IN2014CN02659A (enExample) 2015-06-26
JP2014531029A (ja) 2014-11-20
WO2013057616A1 (en) 2013-04-25
CN103890588B (zh) 2017-02-15
EP2745118B1 (en) 2020-12-09
EP2745118A1 (en) 2014-06-25
CN103890588A (zh) 2014-06-25
US20140329335A1 (en) 2014-11-06

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