JP6053768B2 - Bcat1阻害剤を使用する治療方法 - Google Patents

Bcat1阻害剤を使用する治療方法 Download PDF

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JP6053768B2
JP6053768B2 JP2014515915A JP2014515915A JP6053768B2 JP 6053768 B2 JP6053768 B2 JP 6053768B2 JP 2014515915 A JP2014515915 A JP 2014515915A JP 2014515915 A JP2014515915 A JP 2014515915A JP 6053768 B2 JP6053768 B2 JP 6053768B2
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cancer
bcat1
moha
cells
cell
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JP2014517037A (ja
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アドニア イー. パパサナスィウ
アドニア イー. パパサナスィウ
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エルゴン ファーマシューティカルズ エルエルシー
エルゴン ファーマシューティカルズ エルエルシー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185Saturated compounds having only one carboxyl group and containing keto groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
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  • Gastroenterology & Hepatology (AREA)
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  • Pulmonology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2014515915A 2011-06-13 2012-06-12 Bcat1阻害剤を使用する治療方法 Expired - Fee Related JP6053768B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161520645P 2011-06-13 2011-06-13
US61/520,645 2011-06-13
PCT/US2012/042046 WO2012173987A2 (en) 2011-06-13 2012-06-12 Methods of treatment using a bcat1 inhibitor

Related Child Applications (1)

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JP2016228528A Division JP6243996B2 (ja) 2011-06-13 2016-11-25 Bcat1阻害剤を使用する治療方法

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JP2014517037A JP2014517037A (ja) 2014-07-17
JP2014517037A5 JP2014517037A5 (https=) 2015-07-23
JP6053768B2 true JP6053768B2 (ja) 2016-12-27

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JP2014515915A Expired - Fee Related JP6053768B2 (ja) 2011-06-13 2012-06-12 Bcat1阻害剤を使用する治療方法
JP2016228528A Expired - Fee Related JP6243996B2 (ja) 2011-06-13 2016-11-25 Bcat1阻害剤を使用する治療方法

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US (1) US9422224B2 (https=)
EP (1) EP2717869B1 (https=)
JP (2) JP6053768B2 (https=)
WO (1) WO2012173987A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9725526B2 (en) 2014-07-30 2017-08-08 Lg Chem, Ltd. Modified conjugated diene polymer, modified rubber composition comprising same, and method for producing modified conjugated diene polymer

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10941109B2 (en) 2011-06-13 2021-03-09 Ergon Pharmaceuticals Llc Compositions and methods of treatment using a BCAT1 inhibitor
ITUB20151014A1 (it) 2015-05-27 2016-11-27 Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro Ligandi del recettore b7h nel trattamento di osteopenia e osteoporosi
CA2999224C (en) * 2015-09-23 2023-10-24 Pfizer Inc. Cells and method of cell culture
JP7256509B2 (ja) * 2016-08-22 2023-04-12 エルゴン ファーマシューティカルズ エルエルシー Bcat1阻害剤を使用する組成物及び治療方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042191A1 (en) * 1999-12-08 2001-06-14 Warner-Lambert Company Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of diabetic retinopathy
WO2002024672A2 (en) * 2000-09-19 2002-03-28 Warner-Lambert Company Llc Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases
NZ551196A (en) * 2004-05-14 2010-08-27 Emisphere Tech Inc Compounds and compositions for delivering active agents
US7842467B1 (en) 2005-05-12 2010-11-30 Celera Corporation Breast disease targets and uses thereof
GB0705400D0 (en) * 2007-03-21 2007-05-02 Univ Aberdeen Therapeutic compounds andm their use
WO2010127452A1 (en) 2009-05-04 2010-11-11 The Royal Institution For The Advancement Of Learning/Mcgill University 5-oxo-ete receptor antagonist compounds
EP2481801A1 (en) 2011-01-28 2012-08-01 Deutsches Krebsforschungszentrum Inhibitors of branched-chain-aminotransferase-1 (BCAT1) for the treatment of neoplasia

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9725526B2 (en) 2014-07-30 2017-08-08 Lg Chem, Ltd. Modified conjugated diene polymer, modified rubber composition comprising same, and method for producing modified conjugated diene polymer
KR101775761B1 (ko) * 2014-07-30 2017-09-19 주식회사 엘지화학 변성 공액 디엔계 중합체, 이를 포함하는 변성 고무 조성물 및 변성 공액 디엔계 중합체의 제조방법

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Publication number Publication date
WO2012173987A2 (en) 2012-12-20
JP2017061539A (ja) 2017-03-30
JP2014517037A (ja) 2014-07-17
EP2717869B1 (en) 2019-02-27
US9422224B2 (en) 2016-08-23
WO2012173987A3 (en) 2013-04-04
EP2717869A2 (en) 2014-04-16
JP6243996B2 (ja) 2017-12-06
US20140128467A1 (en) 2014-05-08
EP2717869A4 (en) 2014-11-26

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