JP6043344B2 - 免疫学的障害の治療のための置換インドール誘導体 - Google Patents
免疫学的障害の治療のための置換インドール誘導体 Download PDFInfo
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- JP6043344B2 JP6043344B2 JP2014510933A JP2014510933A JP6043344B2 JP 6043344 B2 JP6043344 B2 JP 6043344B2 JP 2014510933 A JP2014510933 A JP 2014510933A JP 2014510933 A JP2014510933 A JP 2014510933A JP 6043344 B2 JP6043344 B2 JP 6043344B2
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| PCT/IB2012/052473 WO2012156936A1 (en) | 2011-05-17 | 2012-05-16 | Substituted indole derivatives for the treatment of immunological disorders |
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| BR112015009214A2 (pt) * | 2012-11-07 | 2017-07-04 | Novartis Ag | derivados de indol substituído |
| EP4772247A2 (en) | 2013-08-14 | 2026-07-08 | Novartis AG | Combination therapy comprising ribociclib and fulvestrant for the treatment of cancer |
| CA2923765C (en) | 2013-09-18 | 2021-06-29 | University Of Canberra | Stem cell modulation ii |
| AU2015309686B2 (en) | 2014-08-25 | 2020-05-14 | Epiaxis Therapeutics Pty Ltd | Compositions for modulating cancer stem cells and uses therefor |
| WO2025091442A1 (zh) * | 2023-11-03 | 2025-05-08 | 北京凯因科技股份有限公司 | 一种神经氨酸酶抑制剂及在流感病毒中的应用 |
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| US4925860A (en) | 1987-08-05 | 1990-05-15 | E. I. Du Pont De Nemours And Company | Stable pharmaceutical composition of 3-(hydroxymethyl)-5,5-diphenylhydantoin disodium phosphate ester |
| DE4005970A1 (de) | 1990-02-26 | 1991-08-29 | Boehringer Mannheim Gmbh | Neue trisubstituierte maleinimide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
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| US6204257B1 (en) | 1998-08-07 | 2001-03-20 | Universtiy Of Kansas | Water soluble prodrugs of hindered alcohols |
| PL357441A1 (en) * | 1999-10-12 | 2004-07-26 | F.Hoffmann-La Roche Ag | Substituted pyrroles as antiproliferative agents for the treatment of cancer |
| CN1253449C (zh) * | 2000-11-07 | 2006-04-26 | 诺瓦提斯公司 | 作为蛋白激酶c抑制剂的吲哚基马来酰亚胺衍生物 |
| KR101016969B1 (ko) | 2001-12-21 | 2011-02-25 | 에이자이 아이엔씨. | 알콜 및 페놀의 수용성 포스포노옥시메틸 유도체를제조하는 방법 |
| RU2316317C2 (ru) | 2001-12-28 | 2008-02-10 | Эм-Джи-Ай Джи-Пи, Инк. | Составленные на основе воды фармацевтические композиции водорастворимых пролекарств пропофола |
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| RU2297216C2 (ru) | 2002-04-08 | 2007-04-20 | Эм-Джи-Ай Джи-Пи,Инк. | Фармацевтические композиции, содержащие растворимые в воде пролекарства пропофола, и способы их применения |
| AU2003223104A1 (en) | 2003-03-19 | 2004-10-11 | Suven Life Sciences Limited | A process for the preparation of indolymaleimides |
| US7449458B2 (en) | 2005-01-19 | 2008-11-11 | Rigel Pharmaceuticals, Inc. | Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
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| US20070203236A1 (en) | 2006-01-11 | 2007-08-30 | Smith Jeffrey W | Novel antagonists of the human fatty acid synthase thioesterase |
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| WO2008064274A1 (en) | 2006-11-21 | 2008-05-29 | Rigel Pharmaceuticals, Inc. | Prodrug salts of 2, 4-pyrimidinediamine compounds and their uses |
| US20150018301A1 (en) | 2009-11-06 | 2015-01-15 | The Johns Hopkins University | LRRK-2-Mediated Neuronal Toxicity |
| CN101812097B (zh) | 2010-04-17 | 2012-04-25 | 中国海洋大学 | 吲哚咔唑和双吲哚马来酰亚胺生物碱及其制备方法和应用 |
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| US8703782B2 (en) | 2014-04-22 |
| UY34072A (es) | 2013-01-03 |
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| CA2835169A1 (en) | 2012-11-22 |
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| CA2835169C (en) | 2019-05-14 |
| US20140179634A1 (en) | 2014-06-26 |
| EA201391710A1 (ru) | 2014-03-31 |
| EP2709998A1 (en) | 2014-03-26 |
| US20130157980A1 (en) | 2013-06-20 |
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| KR20140023354A (ko) | 2014-02-26 |
| EP2709998B1 (en) | 2016-01-06 |
| WO2012156936A1 (en) | 2012-11-22 |
| US9029396B2 (en) | 2015-05-12 |
| BR112013029416A2 (pt) | 2017-01-31 |
| JP2014518870A (ja) | 2014-08-07 |
| CN103534250B (zh) | 2016-05-11 |
| TW201249858A (en) | 2012-12-16 |
| AR088414A1 (es) | 2014-06-11 |
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