JP6001557B2 - 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 - Google Patents
抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 Download PDFInfo
- Publication number
- JP6001557B2 JP6001557B2 JP2013549652A JP2013549652A JP6001557B2 JP 6001557 B2 JP6001557 B2 JP 6001557B2 JP 2013549652 A JP2013549652 A JP 2013549652A JP 2013549652 A JP2013549652 A JP 2013549652A JP 6001557 B2 JP6001557 B2 JP 6001557B2
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- JP
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- seq
- antibody
- ptprs
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- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Mycology (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013549652A JP6001557B2 (ja) | 2011-04-28 | 2012-04-27 | 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011101752 | 2011-04-28 | ||
| JP2011101752 | 2011-04-28 | ||
| PCT/JP2012/061795 WO2012148003A1 (en) | 2011-04-28 | 2012-04-27 | ANTI-HUMAN RECEPTOR-TYPE PROTEIN TYROSINE PHOSPHATASE σ ANTIBODY |
| JP2013549652A JP6001557B2 (ja) | 2011-04-28 | 2012-04-27 | 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016170634A Division JP6412072B2 (ja) | 2011-04-28 | 2016-09-01 | 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014524733A JP2014524733A (ja) | 2014-09-25 |
| JP2014524733A5 JP2014524733A5 (enExample) | 2015-07-16 |
| JP6001557B2 true JP6001557B2 (ja) | 2016-10-05 |
Family
ID=46147004
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549652A Active JP6001557B2 (ja) | 2011-04-28 | 2012-04-27 | 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 |
| JP2016170634A Active JP6412072B2 (ja) | 2011-04-28 | 2016-09-01 | 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016170634A Active JP6412072B2 (ja) | 2011-04-28 | 2016-09-01 | 抗ヒト受容体型プロテインチロシンホスファターゼσ抗体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9803026B2 (enExample) |
| EP (2) | EP3232202B1 (enExample) |
| JP (2) | JP6001557B2 (enExample) |
| KR (1) | KR101873614B1 (enExample) |
| CN (1) | CN103703372B (enExample) |
| AU (2) | AU2012248158C1 (enExample) |
| CA (1) | CA2834243C (enExample) |
| ES (2) | ES2788183T3 (enExample) |
| HU (2) | HUE054211T2 (enExample) |
| IL (1) | IL229127A (enExample) |
| MX (1) | MX352599B (enExample) |
| PL (2) | PL2702412T3 (enExample) |
| PT (2) | PT3232202T (enExample) |
| RU (2) | RU2013152816A (enExample) |
| SG (3) | SG10201503257WA (enExample) |
| WO (1) | WO2012148003A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE027154T2 (en) | 2007-07-02 | 2016-08-29 | Oncomed Pharm Inc | Preparations and procedures for the treatment and diagnosis of cancer |
| KR101873614B1 (ko) * | 2011-04-28 | 2018-07-02 | 에스비아이 바이오테크 가부시키가이샤 | 항인간 수용체형 단백질 티로신 포스파타아제 σ 항체 |
| EP2731625B1 (en) | 2011-07-15 | 2018-04-18 | OncoMed Pharmaceuticals, Inc. | Rspo binding agents and uses thereof |
| AU2013289990B2 (en) | 2012-07-13 | 2018-06-14 | Oncomed Pharmaceuticals, Inc. | RSPO3 binding agents and uses thereof |
| EP2877494B1 (en) * | 2012-07-23 | 2020-07-15 | La Jolla Institute for Allergy and Immunology | Ptprs and proteoglycans in autoimmune disease |
| WO2015117199A1 (en) * | 2014-02-04 | 2015-08-13 | Monash University | Anti-metalloprotease antibody for diagnosis and treatment of cancers |
| US11160873B2 (en) * | 2014-02-04 | 2021-11-02 | Monash University | Anti-metalloprotease antibody for diagnosis and treatment of cancers |
| JP2017528523A (ja) | 2014-09-16 | 2017-09-28 | オンコメッド ファーマシューティカルズ インコーポレイテッド | 線維性疾患の治療 |
| KR20170094787A (ko) * | 2014-12-18 | 2017-08-21 | 에프. 호프만-라 로슈 아게 | Cdc 유발 항체를 측정하기 위한 검정 및 방법 |
| BR112019019595A2 (pt) * | 2017-03-23 | 2020-04-14 | Univ Pennsylvania | anticorpo, métodos para tratar uma doença ou distúrbio mediado pela via do complemento em um indivíduo e para reduzir a atividade de um sistema complemento de um indivíduo, e, célula |
| JP2020514394A (ja) * | 2017-03-24 | 2020-05-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 異常な線維芽細胞におけるプロテオグリカンの不規則性及びそれに基づく治療法 |
| US11242398B2 (en) | 2017-08-01 | 2022-02-08 | Remd Biotherapeutics, Inc. | Anti-OX40 antibodies and methods of activating OX40 |
| CN112770723B (zh) | 2018-07-25 | 2024-08-02 | 阿克罗斯生物科学公司 | Cldn 18.2特异性单克隆抗体及其使用方法 |
| GB201910899D0 (en) * | 2019-07-31 | 2019-09-11 | Scancell Ltd | Binding members |
| BR112022006177A2 (pt) * | 2019-10-04 | 2022-08-23 | Albert Einstein College Medicine | Kir3dl3 é um receptor inibidor do sistema imune e do mesmo |
| WO2023010132A1 (en) | 2021-07-30 | 2023-02-02 | The Regents Of The University Of California | Ptprs in autoimmunity |
| CN114426582B (zh) * | 2022-01-07 | 2022-11-25 | 陕西脉元生物科技有限公司 | 一种神经特异性烯醇化酶单克隆抗体及其制备方法和应用 |
| CN116041526B (zh) * | 2022-11-14 | 2023-09-29 | 华中农业大学 | 一种鼠抗草鱼IgT单克隆抗体及其制备方法和应用 |
| WO2024124164A2 (en) * | 2022-12-09 | 2024-06-13 | The Trustees Of The University Of Pennsylvania | Compositions and methods for delivery of immunostimulatory cytokines to chimeric antigen receptor immune cells |
| AU2024231685A1 (en) * | 2023-03-03 | 2025-09-25 | Case Western Reserve University | Cell adhesion molecule targeted immunotherapies |
| CN118994384B (zh) * | 2024-08-09 | 2025-09-26 | 陕西脉元生物科技有限公司 | 抗Ri的人源化单克隆抗体及其应用和基于其的检测方法 |
| CN119874900B (zh) * | 2025-03-06 | 2025-10-17 | 吉林大学 | 一种单克隆抗体及其在制备治疗肿瘤药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09504689A (ja) | 1993-10-01 | 1997-05-13 | ニューヨーク ユニバーシティー | 新規な受容体型ホスホチロシンホスファターゼσ |
| AU2003252328A1 (en) | 2002-08-01 | 2004-02-23 | Ginkgo Biomedical Research Institute Co., Ltd. | Method of detecting mouse interferon-producing cells |
| CN1761682A (zh) * | 2003-03-14 | 2006-04-19 | 大正制药株式会社 | 单克隆抗体与产生该单克隆抗体的杂交瘤 |
| WO2005102456A1 (en) | 2004-03-27 | 2005-11-03 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Composition and method for cancer treatment |
| US20080008719A1 (en) | 2004-07-10 | 2008-01-10 | Bowdish Katherine S | Methods and compositions for the treatment of prostate cancer |
| JP2009510102A (ja) | 2005-09-29 | 2009-03-12 | ヴァイラル ロジック システムズ テクノロジー コーポレーション | 免疫調節組成物およびその使用 |
| WO2009003274A1 (en) * | 2007-06-29 | 2009-01-08 | The Hospital For Sick Children | Susceptibility gene for inflammatory bowel disease |
| WO2010056332A1 (en) * | 2008-11-14 | 2010-05-20 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| WO2011022462A2 (en) * | 2009-08-18 | 2011-02-24 | President And Fellows Of Harvard College | Neural regeneration |
| WO2011097327A2 (en) * | 2010-02-02 | 2011-08-11 | La Jolla Institute For Allergy & Immunology | Compositions and methods of modulating receptor protein tyrosine phosphatases |
| KR101873614B1 (ko) * | 2011-04-28 | 2018-07-02 | 에스비아이 바이오테크 가부시키가이샤 | 항인간 수용체형 단백질 티로신 포스파타아제 σ 항체 |
-
2012
- 2012-04-27 KR KR1020137028325A patent/KR101873614B1/ko active Active
- 2012-04-27 PL PL12722557T patent/PL2702412T3/pl unknown
- 2012-04-27 HU HUE17174348A patent/HUE054211T2/hu unknown
- 2012-04-27 WO PCT/JP2012/061795 patent/WO2012148003A1/en not_active Ceased
- 2012-04-27 JP JP2013549652A patent/JP6001557B2/ja active Active
- 2012-04-27 CN CN201280020580.XA patent/CN103703372B/zh active Active
- 2012-04-27 ES ES17174348T patent/ES2788183T3/es active Active
- 2012-04-27 PT PT171743487T patent/PT3232202T/pt unknown
- 2012-04-27 ES ES12722557.1T patent/ES2638088T3/es active Active
- 2012-04-27 RU RU2013152816/10A patent/RU2013152816A/ru not_active Application Discontinuation
- 2012-04-27 EP EP17174348.7A patent/EP3232202B1/en active Active
- 2012-04-27 SG SG10201503257WA patent/SG10201503257WA/en unknown
- 2012-04-27 PT PT127225571T patent/PT2702412T/pt unknown
- 2012-04-27 SG SG2013079066A patent/SG194614A1/en unknown
- 2012-04-27 SG SG10202108240VA patent/SG10202108240VA/en unknown
- 2012-04-27 RU RU2017118262A patent/RU2715642C2/ru active
- 2012-04-27 HU HUE12722557A patent/HUE034752T2/en unknown
- 2012-04-27 CA CA2834243A patent/CA2834243C/en active Active
- 2012-04-27 PL PL17174348T patent/PL3232202T3/pl unknown
- 2012-04-27 MX MX2013012393A patent/MX352599B/es active IP Right Grant
- 2012-04-27 AU AU2012248158A patent/AU2012248158C1/en active Active
- 2012-04-27 US US14/113,904 patent/US9803026B2/en active Active
- 2012-04-27 EP EP12722557.1A patent/EP2702412B1/en active Active
-
2013
- 2013-10-28 IL IL229127A patent/IL229127A/en active IP Right Grant
-
2016
- 2016-09-01 JP JP2016170634A patent/JP6412072B2/ja active Active
- 2016-11-23 AU AU2016262677A patent/AU2016262677B2/en active Active
-
2017
- 2017-10-06 US US15/726,669 patent/US10730955B2/en active Active
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