AU2012248158C1 - Anti-human receptor-type protein tyrosine phosphatase sigma antibody - Google Patents

Anti-human receptor-type protein tyrosine phosphatase sigma antibody Download PDF

Info

Publication number
AU2012248158C1
AU2012248158C1 AU2012248158A AU2012248158A AU2012248158C1 AU 2012248158 C1 AU2012248158 C1 AU 2012248158C1 AU 2012248158 A AU2012248158 A AU 2012248158A AU 2012248158 A AU2012248158 A AU 2012248158A AU 2012248158 C1 AU2012248158 C1 AU 2012248158C1
Authority
AU
Australia
Prior art keywords
antibody
cell
seq
set forth
ptprs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2012248158A
Other languages
English (en)
Other versions
AU2012248158B2 (en
AU2012248158A1 (en
Inventor
Minkwon Cho
Mayuki ENDO
Koji Ishida
Yasue SHIBATA
Tomohide YAMAZAKI
Jing Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SBI Biotech Co Ltd
Original Assignee
SBI Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SBI Biotech Co Ltd filed Critical SBI Biotech Co Ltd
Publication of AU2012248158A1 publication Critical patent/AU2012248158A1/en
Application granted granted Critical
Publication of AU2012248158B2 publication Critical patent/AU2012248158B2/en
Priority to AU2016262677A priority Critical patent/AU2016262677B2/en
Publication of AU2012248158C1 publication Critical patent/AU2012248158C1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5058Neurological cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Mycology (AREA)
AU2012248158A 2011-04-28 2012-04-27 Anti-human receptor-type protein tyrosine phosphatase sigma antibody Active AU2012248158C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016262677A AU2016262677B2 (en) 2011-04-28 2016-11-23 Anti-human receptor-type protein tyrosine phosphatase sigma antibody

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011-101752 2011-04-28
JP2011101752 2011-04-28
PCT/JP2012/061795 WO2012148003A1 (en) 2011-04-28 2012-04-27 ANTI-HUMAN RECEPTOR-TYPE PROTEIN TYROSINE PHOSPHATASE σ ANTIBODY

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016262677A Division AU2016262677B2 (en) 2011-04-28 2016-11-23 Anti-human receptor-type protein tyrosine phosphatase sigma antibody

Publications (3)

Publication Number Publication Date
AU2012248158A1 AU2012248158A1 (en) 2014-01-30
AU2012248158B2 AU2012248158B2 (en) 2016-09-08
AU2012248158C1 true AU2012248158C1 (en) 2017-02-02

Family

ID=46147004

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2012248158A Active AU2012248158C1 (en) 2011-04-28 2012-04-27 Anti-human receptor-type protein tyrosine phosphatase sigma antibody
AU2016262677A Active AU2016262677B2 (en) 2011-04-28 2016-11-23 Anti-human receptor-type protein tyrosine phosphatase sigma antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016262677A Active AU2016262677B2 (en) 2011-04-28 2016-11-23 Anti-human receptor-type protein tyrosine phosphatase sigma antibody

Country Status (16)

Country Link
US (2) US9803026B2 (enExample)
EP (2) EP3232202B1 (enExample)
JP (2) JP6001557B2 (enExample)
KR (1) KR101873614B1 (enExample)
CN (1) CN103703372B (enExample)
AU (2) AU2012248158C1 (enExample)
CA (1) CA2834243C (enExample)
ES (2) ES2788183T3 (enExample)
HU (2) HUE054211T2 (enExample)
IL (1) IL229127A (enExample)
MX (1) MX352599B (enExample)
PL (2) PL2702412T3 (enExample)
PT (2) PT3232202T (enExample)
RU (2) RU2013152816A (enExample)
SG (3) SG10201503257WA (enExample)
WO (1) WO2012148003A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE027154T2 (en) 2007-07-02 2016-08-29 Oncomed Pharm Inc Preparations and procedures for the treatment and diagnosis of cancer
KR101873614B1 (ko) * 2011-04-28 2018-07-02 에스비아이 바이오테크 가부시키가이샤 항인간 수용체형 단백질 티로신 포스파타아제 σ 항체
EP2731625B1 (en) 2011-07-15 2018-04-18 OncoMed Pharmaceuticals, Inc. Rspo binding agents and uses thereof
AU2013289990B2 (en) 2012-07-13 2018-06-14 Oncomed Pharmaceuticals, Inc. RSPO3 binding agents and uses thereof
EP2877494B1 (en) * 2012-07-23 2020-07-15 La Jolla Institute for Allergy and Immunology Ptprs and proteoglycans in autoimmune disease
WO2015117199A1 (en) * 2014-02-04 2015-08-13 Monash University Anti-metalloprotease antibody for diagnosis and treatment of cancers
US11160873B2 (en) * 2014-02-04 2021-11-02 Monash University Anti-metalloprotease antibody for diagnosis and treatment of cancers
JP2017528523A (ja) 2014-09-16 2017-09-28 オンコメッド ファーマシューティカルズ インコーポレイテッド 線維性疾患の治療
KR20170094787A (ko) * 2014-12-18 2017-08-21 에프. 호프만-라 로슈 아게 Cdc 유발 항체를 측정하기 위한 검정 및 방법
BR112019019595A2 (pt) * 2017-03-23 2020-04-14 Univ Pennsylvania anticorpo, métodos para tratar uma doença ou distúrbio mediado pela via do complemento em um indivíduo e para reduzir a atividade de um sistema complemento de um indivíduo, e, célula
JP2020514394A (ja) * 2017-03-24 2020-05-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 異常な線維芽細胞におけるプロテオグリカンの不規則性及びそれに基づく治療法
US11242398B2 (en) 2017-08-01 2022-02-08 Remd Biotherapeutics, Inc. Anti-OX40 antibodies and methods of activating OX40
CN112770723B (zh) 2018-07-25 2024-08-02 阿克罗斯生物科学公司 Cldn 18.2特异性单克隆抗体及其使用方法
GB201910899D0 (en) * 2019-07-31 2019-09-11 Scancell Ltd Binding members
BR112022006177A2 (pt) * 2019-10-04 2022-08-23 Albert Einstein College Medicine Kir3dl3 é um receptor inibidor do sistema imune e do mesmo
WO2023010132A1 (en) 2021-07-30 2023-02-02 The Regents Of The University Of California Ptprs in autoimmunity
CN114426582B (zh) * 2022-01-07 2022-11-25 陕西脉元生物科技有限公司 一种神经特异性烯醇化酶单克隆抗体及其制备方法和应用
CN116041526B (zh) * 2022-11-14 2023-09-29 华中农业大学 一种鼠抗草鱼IgT单克隆抗体及其制备方法和应用
WO2024124164A2 (en) * 2022-12-09 2024-06-13 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of immunostimulatory cytokines to chimeric antigen receptor immune cells
AU2024231685A1 (en) * 2023-03-03 2025-09-25 Case Western Reserve University Cell adhesion molecule targeted immunotherapies
CN118994384B (zh) * 2024-08-09 2025-09-26 陕西脉元生物科技有限公司 抗Ri的人源化单克隆抗体及其应用和基于其的检测方法
CN119874900B (zh) * 2025-03-06 2025-10-17 吉林大学 一种单克隆抗体及其在制备治疗肿瘤药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010056332A1 (en) * 2008-11-14 2010-05-20 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504689A (ja) 1993-10-01 1997-05-13 ニューヨーク ユニバーシティー 新規な受容体型ホスホチロシンホスファターゼσ
AU2003252328A1 (en) 2002-08-01 2004-02-23 Ginkgo Biomedical Research Institute Co., Ltd. Method of detecting mouse interferon-producing cells
CN1761682A (zh) * 2003-03-14 2006-04-19 大正制药株式会社 单克隆抗体与产生该单克隆抗体的杂交瘤
WO2005102456A1 (en) 2004-03-27 2005-11-03 The Arizona Board Of Regents On Behalf Of The University Of Arizona Composition and method for cancer treatment
US20080008719A1 (en) 2004-07-10 2008-01-10 Bowdish Katherine S Methods and compositions for the treatment of prostate cancer
JP2009510102A (ja) 2005-09-29 2009-03-12 ヴァイラル ロジック システムズ テクノロジー コーポレーション 免疫調節組成物およびその使用
WO2009003274A1 (en) * 2007-06-29 2009-01-08 The Hospital For Sick Children Susceptibility gene for inflammatory bowel disease
WO2011022462A2 (en) * 2009-08-18 2011-02-24 President And Fellows Of Harvard College Neural regeneration
WO2011097327A2 (en) * 2010-02-02 2011-08-11 La Jolla Institute For Allergy & Immunology Compositions and methods of modulating receptor protein tyrosine phosphatases
KR101873614B1 (ko) * 2011-04-28 2018-07-02 에스비아이 바이오테크 가부시키가이샤 항인간 수용체형 단백질 티로신 포스파타아제 σ 항체

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010056332A1 (en) * 2008-11-14 2010-05-20 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells

Also Published As

Publication number Publication date
PT2702412T (pt) 2017-11-02
SG10201503257WA (en) 2015-06-29
IL229127A (en) 2017-11-30
EP3232202A1 (en) 2017-10-18
US20180155446A1 (en) 2018-06-07
PL3232202T3 (pl) 2020-10-05
JP6001557B2 (ja) 2016-10-05
JP2017048183A (ja) 2017-03-09
ES2638088T3 (es) 2017-10-18
MX2013012393A (es) 2014-04-30
AU2016262677A1 (en) 2016-12-08
CN103703372A (zh) 2014-04-02
US10730955B2 (en) 2020-08-04
AU2016262677B2 (en) 2018-08-30
RU2017118262A3 (enExample) 2018-11-02
SG194614A1 (en) 2013-12-30
EP3232202B1 (en) 2020-02-19
EP2702412B1 (en) 2017-07-26
MX352599B (es) 2017-11-30
JP6412072B2 (ja) 2018-10-24
KR101873614B1 (ko) 2018-07-02
IL229127A0 (en) 2013-12-31
WO2012148003A1 (en) 2012-11-01
CA2834243A1 (en) 2012-11-01
AU2012248158B2 (en) 2016-09-08
AU2012248158A1 (en) 2014-01-30
RU2715642C2 (ru) 2020-03-02
ES2788183T3 (es) 2020-10-20
CN103703372B (zh) 2018-01-26
HUE034752T2 (en) 2018-02-28
RU2013152816A (ru) 2015-06-10
US9803026B2 (en) 2017-10-31
HUE054211T2 (hu) 2021-08-30
US20140127223A1 (en) 2014-05-08
CA2834243C (en) 2019-08-27
PL2702412T3 (pl) 2018-01-31
SG10202108240VA (en) 2021-09-29
JP2014524733A (ja) 2014-09-25
KR20140033024A (ko) 2014-03-17
EP2702412A1 (en) 2014-03-05
PT3232202T (pt) 2020-05-22
BR112013027631A2 (pt) 2022-01-04
RU2017118262A (ru) 2018-11-02

Similar Documents

Publication Publication Date Title
US10730955B2 (en) Polynucleotides encoding anti-human receptor-type protein tyrosine phosphatase sigma antibodies
KR101585532B1 (ko) 항-ilt7 항체
US10336834B2 (en) Methods of using anti-phospholipase D4 antibodies
BR112013027631B1 (pt) Método para a produção de anticorpo monoclonal ou fragmento que inclui uma região de ligação ao antígeno do mesmo, anticorpo monoclonal ou um fragmento que inclui uma região de ligação ao antígeno do mesmo, hibridoma, método para a detecção de uma célula dendrítica plasmocitóide, uso de um anticorpo monoclonal ou um fragmento que inclui uma região de ligação ao antígeno do mesmo, e método ex vivo para suprimir a atividade de uma célula dendrítica plasmocitóide

Legal Events

Date Code Title Description
NB Applications allowed - extensions of time section 223(2)

Free format text: THE TIME IN WHICH TO ENTER THE NATIONAL PHASE HAS BEEN EXTENDED TO 28 JAN 2014 .

DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 14 OCT 2016

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 14 OCT 2016

FGA Letters patent sealed or granted (standard patent)