JP5987249B2 - 溶液中でミクロンサイズの物体を検出するための光学的検出方法 - Google Patents

溶液中でミクロンサイズの物体を検出するための光学的検出方法 Download PDF

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JP5987249B2
JP5987249B2 JP2012533626A JP2012533626A JP5987249B2 JP 5987249 B2 JP5987249 B2 JP 5987249B2 JP 2012533626 A JP2012533626 A JP 2012533626A JP 2012533626 A JP2012533626 A JP 2012533626A JP 5987249 B2 JP5987249 B2 JP 5987249B2
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detection method
optical detection
droplet
droplets
particles
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JP2013507630A (ja
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アリエ、セドリック
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コミシリア ア レネルジ アトミック エ オ エナジーズ オルタネティヴズ
コミシリア ア レネルジ アトミック エ オ エナジーズ オルタネティヴズ
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4022—Concentrating samples by thermal techniques; Phase changes
    • G01N2001/4027—Concentrating samples by thermal techniques; Phase changes evaporation leaving a concentrated sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1481—Optical analysis of particles within droplets

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  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2012533626A 2009-10-16 2010-10-14 溶液中でミクロンサイズの物体を検出するための光学的検出方法 Active JP5987249B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0904966A FR2951542B1 (fr) 2009-10-16 2009-10-16 Procede de detection optique d'objets micrometriques en solution
FR0904966 2009-10-16
PCT/EP2010/065382 WO2011045360A1 (fr) 2009-10-16 2010-10-14 Procédé de détection optique d'objets micrométriques en solution

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JP2015222347A Division JP2016057307A (ja) 2009-10-16 2015-11-12 溶液中でミクロンサイズの物体を検出するための光学的検出方法

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JP2013507630A JP2013507630A (ja) 2013-03-04
JP5987249B2 true JP5987249B2 (ja) 2016-09-07

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JP2012533626A Active JP5987249B2 (ja) 2009-10-16 2010-10-14 溶液中でミクロンサイズの物体を検出するための光学的検出方法
JP2015222347A Pending JP2016057307A (ja) 2009-10-16 2015-11-12 溶液中でミクロンサイズの物体を検出するための光学的検出方法

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US (1) US8605265B2 (enExample)
EP (1) EP2488847B1 (enExample)
JP (2) JP5987249B2 (enExample)
CN (1) CN102575977A (enExample)
FR (1) FR2951542B1 (enExample)
IN (1) IN2012DN03099A (enExample)
WO (1) WO2011045360A1 (enExample)

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US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
CA2778725C (en) 2009-10-28 2019-04-30 Alentic Microscience Inc. Microscopy imaging
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US8767069B2 (en) * 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
FR2991457B1 (fr) * 2012-06-01 2014-07-18 Commissariat Energie Atomique Procede et systeme de caracterisation de la vitesse de deplacement de particules contenues dans un liquide, telles que des particules sanguines
FR2993276B1 (fr) 2012-07-12 2015-07-24 Commissariat Energie Atomique Composition pour la detection optique de particules, comprenant de l'eau, les particules, un surfactant et un polymere hydrophile, systeme et procede de detection optique associes
FR2993372B1 (fr) * 2012-07-13 2015-04-10 Commissariat Energie Atomique Procede et systeme de reconstruction de proprietes optiques d'objets diffractants baignant dans un milieu liquide
FR2998493B1 (fr) * 2012-11-27 2015-02-13 Commissariat Energie Atomique Procede de formation d'un film liquide sur un support
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
WO2014121388A1 (en) * 2013-02-06 2014-08-14 Alentic Microscience Inc. Detecting and using light representative of a sample
FR3002634B1 (fr) * 2013-02-28 2015-04-10 Commissariat Energie Atomique Procede d'observation d'au moins un objet, tel qu'une entite biologique, et systeme d'imagerie associe
WO2014141034A2 (en) * 2013-03-15 2014-09-18 Richard Harry Turner A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids
CA2953620C (en) 2013-06-26 2020-08-25 Alentic Microscience Inc. Sample processing improvements for microscopy
FR3041474A1 (fr) 2015-09-23 2017-03-24 Commissariat Energie Atomique Dispositif d’imagerie sans lentille et procede d’observation associe
FR3062209B1 (fr) * 2017-01-25 2021-08-27 Commissariat Energie Atomique Detecteur optique de particules
CN108844936A (zh) * 2018-07-09 2018-11-20 领航基因科技（杭州）有限公司 一种三维液滴检测系统及检测方法
EP3969604A1 (en) * 2019-05-13 2022-03-23 Vrije Universiteit Brussel Methods and systems for particle characterisation

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FR2192708A5 (enExample) * 1972-07-13 1974-02-08 Ctre Nal Transf Sion San
JP2890730B2 (ja) * 1990-07-27 1999-05-17 ジェイエスアール株式会社 検定液中の微粒子数の測定方法
JPH04316478A (ja) * 1991-04-12 1992-11-06 Nec Corp 生物試料観察装置、システムおよび方法
JPH06311879A (ja) * 1993-03-15 1994-11-08 Nec Corp バイオセンサ
JPH0755664A (ja) * 1993-08-13 1995-03-03 Nikon Corp 細胞及び染色体の標本用基材
EP1249705A3 (en) * 1996-12-31 2003-11-05 Genometrix Genomics Incorporated Multiplexed molecular analysis apparatus and its fabrication method
JP3979718B2 (ja) * 1998-03-23 2007-09-19 大日本印刷株式会社 測定チップ用液滴固定装置及び該固定装置を持つ測定チップ調製装置
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JP4030438B2 (ja) * 2003-01-29 2008-01-09 株式会社トクヤマ 免疫学的測定方法および免疫クロマトグラフィー法測定キット。
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Also Published As

Publication number Publication date
FR2951542B1 (fr) 2011-12-02
JP2016057307A (ja) 2016-04-21
US20110228256A1 (en) 2011-09-22
US8605265B2 (en) 2013-12-10
EP2488847A1 (fr) 2012-08-22
CN102575977A (zh) 2012-07-11
FR2951542A1 (fr) 2011-04-22
EP2488847B1 (fr) 2017-11-15
JP2013507630A (ja) 2013-03-04
IN2012DN03099A (enExample) 2015-09-18
WO2011045360A1 (fr) 2011-04-21

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